Atopy patch test with Aleuroglyphus ovatus antigen in patients with atopic dermatitis

Abstract

BackgroundEpicutaneous test made with dust mite antigens. ObjectiveEvaluation of the response of the epicutaneous test withAleuroglyphus ovatus antigen in atopic patients. MethodsWe patch tested 119 individuals, 48 with atopic dermatitis, 50 with respiratory allergy and 21 healthy controls. We compare the positive response frequency to a closed patch test usingAleuroglyphus ovatusantigen in different concentrations and 48 and 96h reading times among those individuals. ResultsSix patients with atopic dermatitis (12.5%) and 4 with respiratory atopy (8.0%) had positive reactions. None of the non-atopic controls had a positive response. As the antigen concentration raised, the number of positive reactions to epicutaneous test raised as well. ConclusionOur data suggest a positive relation between Atopy Patch Test positive responses andAleuroglyphus ovatusantigen concentration, no matter the kind of the atopic clinical expression.