GISELLE DE LIMA PEIXOTO

(Fonte: Lattes)
Índice h a partir de 2011
6
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico

Resultados de Busca

Agora exibindo 1 - 10 de 18
  • conferenceObject
    Role of cardiac arrhythmias in sudden cardiac death in renal transplant candidates
    (2014) MARTINELLI FILHO, M.; PEIXOTO, G. L.; SILVA, R. T.; SIQUEIRA, S. F.; LIMA, J. J. G.; TEIXEIRA, R. A.; PEDROSA, A. A. A.; COSTA, R.; NISHIOKA, S. A. D.
  • article 16 Citação(ões) na Scopus
    Effects of Cardiac Resynchronization Therapy on Muscle Sympathetic Nerve Activity
    (2014) KUNIYOSHI, Ricardo R.; MARTINELLI, Martino; NEGRAO, Carlos E.; SIQUEIRA, Sergio F.; RONDON, Maria U. P. B.; TROMBETTA, Ivani C.; KUNIYOSHI, Fatima H. S.; LATERZA, Mateus C.; NISHIOKA, Silvana A. D'Orio; COSTA, Roberto; TAMAKI, Wagner T.; CREVELARI, Elizabeth S.; PEIXOTO, Giselle De Lima; RAMIRES, Jose A. F.; KALIL, Roberto
    IntroductionMuscle sympathetic nerve activity (MSNA) is an independent prognostic marker in patients with heart failure (HF). Therefore, its relevance to the treatment of HF patients is unquestionable. ObjectivesIn this study, we investigated the effects of cardiac resynchronization therapy (CRT) on MSNA response at rest and during exercise in patients with advanced HF. MethodsWe assessed 11 HF patients (51 3.4 years; New York Heart Association class III-IV; left ventricular ejection fraction 27.8 2.2%; optimal medical therapy) submitted to CRT. Evaluations were made prior to and 3 months after CRT. MSNA was performed at rest and during moderate static exercise (handgrip). Peak oxygen consumption (VO2) was evaluated by means of cardiopulmonary exercise test. HF patients with advanced NYHA class without CRT and healthy individuals were also studied. ResultsCRT reduced MSNA at rest (48.9 +/- 11.1 bursts/min vs 33.7 +/- 15.3 bursts/min, P < 0.05) and during handgrip exercise (MSNA 62.3 +/- 13.1 bursts/min vs 46.9 +/- 14.3 bursts/min, P < 0.05). Among HF patients submitted to CRT, the peak VO2 increased (12.9 +/- 2.8 mL/kg/min vs 16.5 +/- 3.9 mL/kg/min, P < 0.05) and an inverse correlation between peak VO2 and resting MSNA (r = -0.74, P = 0.01) was observed. ConclusionsIn patients with advanced HF and severe systolic dysfunction: (1) a significant reduction of MSNA (at rest and during handgrip) occurred after CRT, and this behavior was significantly superior to HF patients receiving only medical therapy; (2) MSNA reduction after CRT had an inverse correlation with O-2 consumption outcomes.
  • article 0 Citação(ões) na Scopus
    Right ventricular pacing in Chagas heart disease
    (2018) PEIXOTO, Giselle de Lima; MARTINELLI FILHO, Martino; SIQUEIRA, Sergio Freitas
  • article 4 Citação(ões) na Scopus
    Impact of diabetes mellitus on ischemic cardiomyopathy. Five-year follow-up. REVISION-DM trial
    (2018) HUEB, Thiago; ROCHA, Mauricio S.; SIQUEIRA, Sergio F.; NISHIOKA, Silvana Angelina D'Orio; PEIXOTO, Giselle L.; SACCAB, Marcos M.; LIMA, Eduardo Gomes; GARCIA, Rosa Maria Rahmi; RAMIRES, Jos Antonio F.; KALIL FILHO, Roberto; MARTINELLI FILHO, Martino
    Background: Patients with ischemic cardiomyopathy and severe left ventricular dysfunction have a worse survival prognosis than patients with preserved ventricular function. The role of diabetes in the long-term prognosis of this patient group is unknown. This study investigated whether the presence of diabetes has a long-term impact on left ventricular function. Methods: Patients with coronary artery disease who underwent coronary artery bypass graft surgery, percutaneous coronary intervention, or medical therapy alone were included. All patients had multivessel disease and left ventricular ejection fraction measurements. Overall mortality, nonfatal myocardial infarction, stroke, and additional interventions were investigated. Results: From January 2009 to January 2010, 918 consecutive patients were selected and followed until May 2015. They were separated into 4 groups: G1, 266 patients with diabetes and ventricular dysfunction; G2, 213 patients with diabetes without ventricular dysfunction; G3, 213 patients without diabetes and ventricular dysfunction; and G4, 226 patients without diabetes but with ventricular dysfunction. Groups 1, 2, 3, and 4, respectively, had a mortality rate of 21.6, 6.1, 4.2, and 10.6% (P < .001); nonfatal myocardial infarction of 5.3, .5, 7.0, and 2.6% (P < .001); stroke of .40, .45, .90, and .90% (P = NS); and additional intervention of 3.8, 11.7, 10.3, and 2.6% (P < .001). Conclusion: In this sample, regardless of the treatment previously received patients with or without diabetes and preserved ventricular function experienced similar outcomes. However, patients with ventricular dysfunction had a worse prognosis compared with those with normal ventricular function; patients with diabetes had greater mortality than patients without diabetes.
  • conferenceObject
    Role of impedance cardiography in predicting clinical near-term outcomes of patients with cardiac resynchronization therapy
    (2014) MARTINELLI FILHO, MMartino; PEIXOTO, G. L.; SIQUEIRA, S. F.; LENSI, M. M.; TRINDADE, R. H. L.; NISHIOKA, S. A. D.; TEIXEIRA, R. A.; PEDROSA, A. A. A.; COSTA, R.
  • article 5 Citação(ões) na Scopus
    Pacemaker-related infection detected by F-18-fluorodeoxyglucose positron emission tomography-computed tomography
    (2014) PEIXOTO, Giselle de Lima; SICILIANO, Rinaldo Focaccia; CAMARGO, Raphael Abegao; BUENO, Fabiana Lucas; SOARES JUNIOR, Jose; COSTA, Roberto; STRABELLI, Tania Mara Varejao; MARTINELLI FILHO, Martino
    Lead endocarditis (LE) is one of the most feared complications and remains a challenging diagnosis in cardiology due to the possibility of an obscure clinical course and symptoms, leading to a delayed diagnosis, or even no diagnosis. F-18-fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET/CT) appears to be a valuable imaging technique and has been shown to have advantages in the diagnosis of patients with fever of unknown origin. We present the case of a 52-year-old man with a 3-year history of intermittent fever, chills, anemia, and weight loss (13 kg). He was submitted to an extensive investigation to clarify his symptoms and all results were negative. LE was finally diagnosed by FDG PET/CT. This examination could become a useful noninvasive method for the detection of LE at an earlier stage, thus avoiding repeated tests and reducing the length of hospital stay.
  • article 1 Citação(ões) na Scopus
    Effect of chronic kidney disease in ischemic cardiomyopathy Long-term follow-up-REVISION-DM2 trial
    (2019) HUEB, Thiago Ovanessian; LIMA, Eduardo Gomes; ROCHA, Mauricio S.; SIQUEIRA, Sergio F.; NISHIOKA, Silvana Angelina Dorio; PEIXOTO, Giselle L.; SACCAB, Marcos M.; GARCIA, Rosa Maria Rahmi; RAMIRES, Jose Antonio F.; KALIL FILHO, Roberto; MARTINELLI FILHO, Martino
    A strong association exists between chronic kidney disease (CKD) and coronary artery disease (CAD). The role of CKD in the long-term prognosis of CAD patients with versus those without CKD is unknown. This study investigated whether CKD affects ventricular function. From January 2009 to January 2010, 918 consecutive patients were selected from an outpatient database. Patients had undergone percutaneous, surgical, or clinical treatment and were followed until May 2015. In patients with preserved renal function (n = 405), 73 events (18%) occurred, but 108 events (21.1%) occurred among those with CKD (n = 513) (P < .001). Regarding left ventricular ejection fraction (LVEF) <50%, we found 84 events (21.5%) in CKD patients and 12 (11.8%) in those with preserved renal function (P < .001). The presence of LVEF <50% brought about a modification effect. Death occurred in 22 (5.4%) patients with preserved renal function and in 73 (14.2%) with CKD (P < .001). In subjects with LVEF <50%, 66 deaths (16.9%) occurred in CKD patients and 7 (6.9%) in those with preserved renal function (P = .001). No differences were found in CKD strata regarding events or overall death among those with preserved LVEF. In a multivariate model, creatinine clearance remained an independent predictor of death (P < .001). We found no deleterious effects of CKD in patients with CAD when ventricular function was preserved. However, there was a worse prognosis in patients with CKD and ventricular dysfunction. Resgistry number is ISRCTN17786790 at .
  • conferenceObject
    Chagas cardiomyopathy patients with pacemaker: predictors of left ventricular remodeling
    (2014) PEIXOTO, G.; MADIA, R. O.; SIQUEIRA, S. F.; LENSI, M. M.; TEIXEIRA, R. A.; NISHIOKA, S. A. D.; PEDROSA, A. A. A.; SACCAB, M. G. M.; COSTA, R.; MARTINELLI, M.
  • conferenceObject
    Risk Factors for Sudden Death in Chagas Cardiomyopathy
    (2015) PEIXOTO, Giselle L.; SIQUEIRA, Sergio; NISHIOKA, Silvana; PEDROSA, Anisio; TEIXEIRA, Ricardo; COSTA, Roberto; MARTINELLI, Martino
  • conferenceObject
    Pacinchagas-crt: A Cohort Study of Cardiac Resynchronization Therapy in Patients With Chronic Chagas Cardiomyopathy
    (2015) MARTINELLI, Martino; PEIXOTO, Giselle L.; SIQUEIRA, Sergio; SANTOS, Johnny; MARTINS, Sergio; NISHIOKA, Silvana; PEDROSA, Anisio; TEIXEIRA, Ricardo; COSTA, Roberto