ELDER LANZANI FREITAS

(Fonte: Lattes)
Índice h a partir de 2011
3
Projetos de Pesquisa
Unidades Organizacionais
Instituto de Psiquiatria, Hospital das Clínicas, Faculdade de Medicina - Médico

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Agora exibindo 1 - 10 de 12
  • conferenceObject
    Association between Childhood Adversity and Ultra-High Risk for Psychosis Status in a Populational Sample of Sao Paulo, Brazil
    (2017) LOCH, Alexandre; ALVES, Tania Maria; FREITAS, Elder Lanzani; HORTENCIO, Lucas; ANDRADE, Julio Cesar; BILT, Martinus Theodorus van de; FONTONI, Marcos Roberto; SERPA, Mauricio; CHIANCA, Camille; GATTAZ, Wagner Farid; ROESSLER, Wulf
  • article 3 Citação(ões) na Scopus
    Profile of Trypanosoma cruzi Reactivity in a Population at High Risk for Endemic Pemphigus Foliaceus (Fogo Selvagem)
    (2012) SOUSA JR., Joaquim X.; DIAZ, Luis A.; EATON, Donald P.; HANS-FILHO, Guenter; FREITAS, Elder Lanzani de; DELGADO, Livia; ICHIMURA, Ligia Maria F.; CRISTALDI, Flavia; ORLANDI, Renata; KESPER JR., Norival; UMEZAWA, Eufrosina S.; RIVITTI, Evandro A.; AOKI, Valeria
    Fogo Selvagem (FS) is an autoimmune bullous disease with pathogenic IgG autoantibodies recognizing desmoglein 1 (Dsg1), a desmosomal glycoprotein. In certain settlements of Brazil, a high prevalence of FS (3%) is reported, suggesting environmental factors as triggers of the autoimmune response. Healthy individuals from endemic areas recognize nonpathogenic epitopes of Dsg1, and exposure to hematophagous insects is a risk factor for FS. Fogo selvagem and Chagas disease share some geographic sites, and anti-Dsg1 has been detected in Chagas patients. Indeterminate Chagas disease was identified in a Brazilian Amerindian population of high risk for FS. In counterpart, none of the FS patients living in the same geographic region showed reactivity against Trypanosoma cruzi. The profile of anti-Dsg1 antibodies showed positive results in 15 of 40 FS sera and in 33 of 150 sera from healthy individuals from endemic FS sites, and no cross-reactivity between Chagas disease and FS was observed.
  • bookPart
    Transtorno de conduta e transtorno opositor e desafiador
    (2019) FREITAS, Elder Lanzani; FONDELLO, Marina Aranha; MEDEIROS FILHO, Mauro Victor de
  • conferenceObject
    PERCEPTUAL ABNORMALITIES AND RELIGIOSITY IN ULTRA HIGH-RISK FOR PSYCHOSIS (UHR) INDIVIDUALS IN A LATIN AMERICAN POPULATIONAL SAMPLE RESULTS FROM THE SAO PAULO SSAPP COHORT
    (2018) LOCH, Alexandre; CHIANCA, Camille; FREITAS, Elder Lanzani; ANDRADE, Julio Cesar; ALVES, Tania Maria; SERPA, Mauricio Henriques; HORTENCIO, Lucas; BILT, Martinus Theodorus van de; GATTAZ, Wagner; ROSSLER, Wulf
  • conferenceObject
    ASSOCIATION BETWEEN CHILDHOOD ADVERSITY AND ULTRA-HIGH RISK FOR PSYCHOSIS STATUS IN A POPULATIONAL SAMPLE OF SAO PAULO, BRAZIL
    (2017) LOCH, Alexandre; ALVES, Tania Maria; FREITAS, Elder Lanzani; HORTENCIO, Lucas; ANDRADE, Julio Cesar; BILT, Martinus Theodorus van de; FONTONI, Marcos Roberto; SERPA, Mauricio; CHIANCA, Camille; GATTAZ, Wagner Farid; ROESSLER, Wulf
  • article 3 Citação(ões) na Scopus
    Influence of migration on the thought process of individuals at ultra-high risk for psychosis
    (2021) NOGUEIRA, Arthur S.; ANDRADE, Julio C.; SERPA, Mauricio H.; ALVES, Tania M.; FREITAS, Elder L.; HORTENCIO, Lucas; BILT, Martinus T. van de; GATTAZ, Wagner F.; LOCH, Alexandre A.; ROSSLER, Wulf
    Objective: To assess the influence of migration on the psychopathological presentation of individuals at ultra-high risk for psychosis (UHR) in Sao Paulo, Brazil. Methods: This study is part of the Subclinical Symptoms and Prodromal Psychosis (SSAPP) project, a cohort study in Sao Paulo, Brazil, designed to follow individuals at UHR. After screening with the Prodromal Questionnaire (PQ) and a clinical interview, the Global Assessment of Functioning (GAF) was administered, a neuropsychological assessment was performed, sociodemographic and migration data were obtained. We then analyzed UHR individuals who had migration data to see if migration had any effect on their cognition and psychopathology. Chi-square tests were used for categorical variables, and Student's t test or analysis of variance (ANOVA) were used for nonparametric and parametric distributions, respectively. Results: The sample was composed of 42 at-risk subjects, of whom 5 had a migration history in the past two generations. Those with migration history showed significantly more formal thought disturbances (p = 0.012) and sleeping problems (p = 0.033) compared to those without. Conclusions: Our data reinforce migration as a risk factor for psychosis in developing countries as well, and highlights the importance of studying the specific effect of this factor in UHR psychopathology.Y
  • article 3 Citação(ões) na Scopus
    Relationship Between Symptomatic Dimensions and Global Functioning of Non-Help-Seeking Individuals at Risk for Psychosis
    (2020) AYOUB, Ibrahim Ali; ANDRADE, Julio Cesar; SERPA, Mauricio Henriques; ALVES, Tania Maria; HORTENCIO, Lucas; FREITAS, Elder Lanzani; BILT, Martinus Theodorus van de; ROESSLER, Wulf; GATTAZ, Wagner Farid; LOCH, Alexandre Andrade
    This study aims to analyze the relationship between the symptomatic dimensions of psychosis and functioning of individuals at risk for psychosis (ultrahigh risk [UHR]) in a non-help-seeking UHR sample from the general population. The sample is the same as the one used in the Brazilian Subclinical Symptoms and Prodromal Psychosis cohort study. We applied questionnaires of functioning (Global Assessment of Functioning Scale) and symptomatic dimensions (Scale of Prodromal Symptoms). Next, we correlated the symptomatic dimensions with functioning. We found a significant relationship between avolition and uncommon thought content with poor functioning, whereas the remaining symptoms were not as relevant. Poor functioning was most related to avolition, a negative symptom, followed by unusual thought content, a positive symptom.
  • conferenceObject
    COGNITIVE PATTERNS ASSOCIATED WITH CHILDHOOD TRAUMA AND RISK FOR PSYCHOSIS IN A POPULATIONAL SAMPLE-A LATENT PROFILE ANALYSIS
    (2019) LOCH, Alexandre; ANDRADE, Julio Cesar; FREITAS, Elder Lanzani; BILT, Martinus Theodorus van de; CHIANCA, Camille; HORTENCIO, Lucas; SERPA, Mauricio Henriques; GATTAZ, Wagner Farld; ROSSLER, Wulf
  • article 21 Citação(ões) na Scopus
    Hearing spirits? Religiosity in individuals at risk for psychosis-Results from the Brazilian SSAPP cohort
    (2019) LOCH, Alexandre Andrade; FREITAS, Elder Lanzani; HORTENCIO, Lucas; CHIANCA, Camille; ALVES, Tania Maria; SERPA, Mauricio Henriques; ANDRADE, Julio Cesar; BILT, Martinus Theodorus van de; GATTAZ, Wagner Farid; ROESSLER, Wulf
    In the last decades, biological and environmental factors related to psychosis were investigated in individuals at ultra-risk for psychosis (UHR) to predict conversion. Although religion relates to psychosis in a variety of ways, it is understudied in subclinical samples. Therefore, we assessed the interplay between religion and prodromal symptoms in 79 UHR and 110 control individuals. They were interviewed with the Duke University Religion Index and the Structured Interview for Prodromal Syndromes (SIPS). Organizational religious activity, a measure of how often someone attends churches/temples, was positively related to perceptual abnormalities/hallucinations (Spearman's rho = 0.262, p = 0.02). This relationship was replicated in a path analysis model (beta = 0342, SE = 0.108, p = 0.002), as well as a link between organizational religious activity and lower ideational richness (beta = 0.401. SE = 0.105, p = 0.000) with no influence of sex, age, religious denomination, or socioeconomic class. Intrinsic religious activity was negatively correlated with suspiciousness (SIPS P2) (beta = -0.028, SE = 0.009, p = 0.002), and non-organizational religious activity was correlated with higher ideational richness (N5) (beta = -0220,SE = 0.097, p = 0.023). We hypothesize that subjects with subclinical psychosis may possibly use churches and other religious organizations to cope with hallucinations. Indeed, Brazil is characterized by a religious syncretism and a strong influence of Spiritism in the popular culture. The mediumistic idea that some might be able to hear and/or see spirits is probably employed to explain subclinical hallucinations in the lay knowledge. Our results emphasize the importance of assessing religion and other region-specific aspects of various cultures when studying UHR individuals. This sort of assessment would enhance understanding of differences in conversion rates, and would help to transpose prevention programs from high-income countries to other settings.
  • conferenceObject
    ILLICIT DRUGS USE AND ULTRA-HIGH RISK (UHR) FOR PSYCHOSIS STATUS IN A LATIN-AMERICAN SAMPLE
    (2018) SERPA, Mauricio; LOCH, Alexandre Andrade; CHIANCA, Camille; FREITAS, Elder; ANDRADE, Julio Cesar; ALVES, Tania Maria; HORTENCIO, Lucas; BILT, Martinus Theodorus van de; GATTAZ, Wagner; ROSSLER, Wulf