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Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina

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Agora exibindo 1 - 2 de 2
  • article 8 Citação(ões) na Scopus
    Prevalence of anti-SARS-CoV-2 antibodies in outpatients of a large public university hospital in Sao Paulo, Brazil
    (2020) OLIVEIRA, Luanda Mara da Silva; TIYO, Bruna Tiaki; SILVA, Lais Teodoro da; FONSECA, Luiz Augusto Marcondes; ROCHA, Rosana Coura; SANTOS, Vera Aparecida dos; CENEVIVA, Carina; BEDIN, Anderson Aparecido; ALMEIDA, Alexandre de; DUARTE, Alberto Jose da Silva; OSHIRO, Telma Miyuki
    Coronavirus disease 19 (COVID-19) is caused by SARS-Cov-2 and the manifestations of this infection range from an absence of symptoms all the way up to severe disease leading to death. To estimate the prevalence of past infection in a population, the most readily available method is the detection of antibodies against the virus. This study has investigated the prevalence of anti-SARS-CoV-2 antibodies in outpatients of the Hospital das Clinicas, in Sao Paulo city (Brazil), which is a large university hospital belonging to the public health system that cares for patients with complex diseases who need tertiary or quaternary medical care. Our serological inquiry was carried out for 6 weeks, with once-a-week blood sampling and included 439 patients from several outpatient services. Overall, 61 patients tested positive for anti-SARS-CoV-2 IgG (13.9%); 56.1 % of the patients live in Sao Paulo city, with the remaining living in other towns of the metropolitan area; 32.8% of the patients testing positive for IgG antibodies to SARS-CoV-2 were asymptomatic, 55.7% developed mild or moderate disease and 11.5% had to be hospitalized. The prevalence of SARS-CoV-2 positive serology was lower among patients who had received the seasonal influenza vaccine compared to the ones who did not. These findings may indicate that those individuals care more about health issues, and/or that they have a better access to health care and/or a better quality of health care service. The large proportion of patients who were unaware of having had contact with SARS-CoV-2 deserves attention, reflecting the scarcity of tests performed in the population.
  • article 22 Citação(ões) na Scopus
    Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Seroprevalence and Risk Factors Among Oligo/Asymptomatic Healthcare Workers: Estimating the Impact of Community Transmission
    (2021) COSTA, Silvia Figueiredo; GIAVINA-BIANCHI, Pedro; BUSS, Lewis; PERES, Carlos Henrique Mesquita; RAFAEL, Mayra Matias; SANTOS, Lanuse Garcia Neves dos; BEDIN, Anderson Aparecido; FRANCISCO, Maria Cristina Peres Braido; SATAKIE, Fatima Mitie; MENEZES, Maria Aparecida Jesus; SECCO, Ligia Maria Dal; CARON, Deyse Mayara Rodrigues; OLIVEIRA, Allan Brum de; FARIA, Matheus Finardi Lima de; PENTEADO, Angelica Sauiuri de Aurelio; SOUZA, Izabel Oliva Marcilio de; PEREIRA, Grazielly de Fatima; PEREIRA, Rafael; PORTO, Ana Paula Matos; ESPINOZA, Evelyn Patricia Sanchez; MENDES-CORREA, Maria Cassia; LAZARI, Carolina dos Santos; KALIL, Jorge; PERONDI, Maria Beatriz de Moliterno; BONFA, Eloisa Silva Dutra de Oliveira; PERREIRA, Antonio Jose; SABINO, Ester; DUARTE, Alberto Jose da Silva; SEGURADO, Aluisio Cotrim; SANTOS, Vera Aparecida dos; LEVIN, Anna S.
    We evaluated the seroprevalence of SARS-CoV-2 and risk factors among 4987 oligo/asymptomatic healthcare workers; seroprevalence was 14% and factors associated with SARS-CoV-2 infection were lower educational level (aOR, 1.93; 95% CI, 1.03-3.60), using public transport to work (aOR, 1.65; 95% CI, 1.07-2.62), and working in cleaning or security (aOR, 2.05; 95% CI, 1.04-4.03).