COVID-19 salivary signature: diagnostic and research opportunities

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Citações na Scopus
Tipo de produção
article
Data de publicação
2021
Título da Revista
ISSN da Revista
Título do Volume
Editora
BMJ PUBLISHING GROUP
Autores
SAPKOTA, Dipak
SOLAND, Tine Merete
GALTUNG, Hilde Kanli
SAND, Lars Peter
GIANNECCHINI, Simone
TO, Kelvin K. W.
GIGLIO, Daniel
HASSEUS, Bengt
Citação
JOURNAL OF CLINICAL PATHOLOGY, v.74, n.6, p.344-349, 2021
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
The COVID-19 (caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)) epidemic started in Wuhan (Hubei Province, China) in mid-December 2019 and quickly spread across the world as a pandemic. As a key to tracing the disease and to implement strategies aimed at breaking the chain of disease transmission, extensive testing for SARS-CoV-2 was suggested. Although nasopharyngeal/oropharyngeal swabs are the most commonly used biological samples for SARS-CoV-2 diagnosis, they have a number of limitations related to sample collection and healthcare personnel safety. In this context, saliva is emerging as a promising alternative to nasopharyngeal/oropharyngeal swabs for COVID-19 diagnosis and monitoring. Saliva collection, being a non-invasive approach with possibility for self-collection, circumvents to a great extent the limitations associated with the use of nasopharyngeal/oropharyngeal swabs. In addition, various salivary biomarkers including the salivary metabolomics offer a high promise to be useful for better understanding of COVID-19 and possibly in the identification of patients with various degrees of severity, including asymptomatic carriers. This review summarises the clinical and scientific basis for the potential use of saliva for COVID-19 diagnosis and disease monitoring. Additionally, we discuss saliva-based biomarkers and their potential clinical and research applications related to COVID-19.
Palavras-chave
diagnostic techniques and procedures, infections, molecular biology, salivary glands, virology
Referências
  1. Aro K, 2017, FRONT PUBLIC HEALTH, V5, DOI 10.3389/fpubh.2017.00077
  2. Azzi L, 2020, J INFECTION, V81, pE45, DOI 10.1016/j.jinf.2020.04.005
  3. Banoei MM, 2017, CRIT CARE, V21, DOI 10.1186/s13054-017-1672-7
  4. Barton LM, 2020, AM J CLIN PATHOL, V153, P725, DOI [10.1093/AJCP/AQAA062, 10.1093/ajcp/aqaa062]
  5. Canatan Duran, 2020, Acta Biomed, V91, P195, DOI 10.23750/abm.v91i2.9534
  6. Castro T, 2018, J ORAL MICROBIOL, V10, DOI 10.1080/20002297.2018.1510712
  7. Chandler JD, 2016, AM J PHYSIOL-REG I, V311, pR906, DOI 10.1152/ajpregu.00298.2016
  8. Chen LZJ, 2020, SSRN
  9. Chen NS, 2020, LANCET, V395, P507, DOI 10.1016/S0140-6736(20)30211-7
  10. Chen Y, 2020, J MED VIROL, V92, P418, DOI 10.1002/jmv.25681
  11. Coutard B, 2020, ANTIVIR RES, V176, DOI 10.1016/j.antiviral.2020.104742
  12. Cruz HM, 2019, BMC INFECT DIS, V19, DOI 10.1186/s12879-019-4183-0
  13. Fehr AR, 2017, ANNU REV MED, V68, P387, DOI 10.1146/annurev-med-051215-031152
  14. Sampaio BCF, 2020, BRAZ J INFECT DIS, V24, P51, DOI 10.1016/j.bjid.2019.11.005
  15. Galhardo LF, 2020, EUR J CLIN INVEST, V50, DOI 10.1111/eci.13219
  16. Goldansaz SA, 2017, PLOS ONE, V12, DOI 10.1371/journal.pone.0177675
  17. Gorbalenya AE, 2020, NAT MICROBIOL, V5, P536, DOI 10.1038/s41564-020-0695-z
  18. Braz-Silva PH, 2021, ORAL DIS, V27, P746, DOI 10.1111/odi.13365
  19. Huang CL, 2020, LANCET, V395, P497, DOI 10.1016/S0140-6736(20)30183-5
  20. Hung IFN, 2020, LANCET, V395, P1695, DOI 10.1016/S0140-6736(20)31042-4
  21. Kaczor-Urbanowicz KE, 2017, EXP BIOL MED, V242, P459, DOI 10.1177/1535370216681550
  22. Kojima NTF., 2020, MEDRXIV
  23. Leon-Icaza SA., 2019, EXRNA, V1, DOI [10.1186/s41544-018-0004-7, DOI 10.1186/S41544-018-0004-7]
  24. Li RY, 2020, SCIENCE, V368, P489, DOI 10.1126/science.abb3221
  25. Lima DP, 2010, INT J INFECT DIS, V14, pE184, DOI 10.1016/j.ijid.2009.04.022
  26. Lin CY, 2020, CLIN CHEM LAB MED, V58, P1089, DOI 10.1515/cclm-2020-0187
  27. Liu L, 2011, J VIROL, V85, P4025, DOI 10.1128/JVI.02292-10
  28. Liu R, 2020, CLIN CHIM ACTA, V505, P172, DOI 10.1016/j.cca.2020.03.009
  29. Lu BJ, 2010, IMMUNOLOGY, V130, P254, DOI 10.1111/j.1365-2567.2010.03231.x
  30. Malamud Daniel, 2011, Dent Clin North Am, V55, P159, DOI 10.1016/j.cden.2010.08.004
  31. Marques JS, 2018, MEDIAT INFLAMM, V2018, DOI 10.1155/2018/6020625
  32. Martelli F, 2018, VIRUS RES, V249, P1, DOI 10.1016/j.virusres.2018.03.002
  33. O'Brien J, 2018, FRONT ENDOCRINOL, V9, DOI 10.3389/fendo.2018.00402
  34. Pang JX, 2020, J CLIN MED, V9, DOI 10.3390/jcm9030623
  35. Pasomsub E, 2021, CLIN MICROBIOL INFEC, V27, DOI 10.1016/j.cmi.2020.05.001
  36. Portilho M, 2017, ORAL DIS, V23, P1072, DOI 10.1111/odi.12692
  37. Sapkota D, 2020, BRIT DENT J, V228, P658, DOI 10.1038/s41415-020-1594-7
  38. Shen B, 2020, CELL, V182, P59, DOI 10.1016/j.cell.2020.05.032
  39. Song J, 2020, J MED VIROL, V92, P2556, DOI 10.1002/jmv.26045
  40. Sullivan Patrick Sean, 2020, JMIR Public Health Surveill, V6, pe19054, DOI 10.2196/19054
  41. To KKW, 2019, CLIN MICROBIOL INFEC, V25, P372, DOI 10.1016/j.cmi.2018.06.009
  42. To KKW, 2020, LANCET INFECT DIS, V20, P565, DOI 10.1016/S1473-3099(20)30196-1
  43. To KKW, 2020, CLIN INFECT DIS, V71, P841, DOI 10.1093/cid/ciaa149
  44. WHO, 2020, 125 WHO
  45. Williams E, 2020, J CLIN MICROBIOL, V58, DOI 10.1128/JCM.00776-20
  46. Wrapp D, 2020, SCIENCE, V367, P1260, DOI [10.1126/science.abb2507, 10.1101/2020.02.11.944462]
  47. Wu CR, 2020, ACTA PHARMACOL SIN B, V10, P766, DOI 10.1016/j.apsb.2020.02.008
  48. Wu D, 2020, NATL SCI REV
  49. Wu JG, 2020, TRAVEL MED INFECT DI, V37, DOI 10.1016/j.tmaid.2020.101673
  50. Wu Q, 2017, SCI REP-UK, V7, DOI 10.1038/s41598-017-09536-z
  51. Wyllie AL FJ., 2020, MEDRXIV
  52. Xie CB, 2020, INT J INFECT DIS, V93, P264, DOI 10.1016/j.ijid.2020.02.050
  53. Xu H, 2020, INT J ORAL SCI, V12, DOI 10.1038/s41368-020-0074-x
  54. Xu J, 2020, J DENT RES, V99, P989, DOI 10.1177/0022034520918518
  55. Zanin M, 2016, CELL HOST MICROBE, V19, P159, DOI 10.1016/j.chom.2016.01.001
  56. Zhang CZ, 2016, INT J ORAL SCI, V8, P133, DOI 10.1038/ijos.2016.38
  57. Zhao JJ, 2020, CLIN INFECT DIS, V71, P2027, DOI 10.1093/cid/ciaa344
  58. Zhou P, 2020, NATURE, V579, P270, DOI 10.1038/s41586-020-2012-7
  59. Zhu N, 2020, NEW ENGL J MED, V382, P727, DOI 10.1056/NEJMoa2001017
  60. Ziegler CGK, 2020, CELL, V181, P1016, DOI 10.1016/j.cell.2020.04.035