Incidental thyroid carcinoma: Correlation between FNAB cytology and pathological examination in 1093 cases

dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorRODRIGUES, Mariana Goncalves
dc.contributor.authorSILVA, Luiz Fernando Ferraz da
dc.contributor.authorARAUJO-FILHO, Vergilius Jose Furtado de
dc.contributor.authorMOSCA, Leticia de Moraes
dc.contributor.authorARAUJO-NETO, Vergilius Jose Furtado de
dc.contributor.authorKOWALSKI, Luiz Paulo
dc.contributor.authorCARNEIRO, Paulo Campos
dc.date.accessioned2022-06-20T15:32:02Z
dc.date.available2022-06-20T15:32:02Z
dc.date.issued2022
dc.description.abstractObjective: To investigate Incidental Thyroid Carcinoma (ITC) by comparing the results of Fine Needle Aspiration Biopsy (FNAB) cytology and the postoperative pathological findings. Methods: Data of 1479 patients who underwent total thyroidectomy were retrieved. Three hundred eighty-six patients were excluded due to insufficient data. Each surgical specimen studied received two histopathological diagnoses: the local diagnosis - for the same area in which the FNAB was performed; and the final diagnosis, which includes a study of the entire surgical specimen. Results: A thousand and ninety-three patients were investigated. FNAB result was malignant in 187 patients, benign in 204, suspicious or indeterminate in 668 cases, and inconclusive in 34 cases. The prevalence of ITC was 15.1%. Most of the ITC in this series was less than 0.5 cm. The incidence of ITC was higher in Bethesda III (17.5% ITC) and IV (19% ITC) than in Bethesda II cases (1.5% false negatives and 9% ITC). Conclusion: Although the incidence of false-negative results in Bethesda II nodules is only 1.5%, 9% of these patients had ITC in the thyroid parenchyma outside the nodule that underwent preoperative FNAB. The incidence of ITC in the same scenario was even higher in Bethesda III (17.5%) and Bethesda IV cases (19%). Ultrasonography-guided FNAB is an excellent method for the assessment of thyroid nodules. However, biopsy sites should be carefully selected. Despite the high incidence of incidentalomas, total thyroidectomy should not always be the treatment of choice due to its rare but potentially serious complications. The findings of the present study can assist future clinical decisions towards active surveillance strategies for the management of papillary thyroid carcinoma.eng
dc.description.indexMEDLINEeng
dc.identifier.citationCLINICS, v.77, article ID 100022, 5p, 2022
dc.identifier.doi10.1016/j.clinsp.2022.100022
dc.identifier.eissn1980-5322
dc.identifier.issn1807-5932
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/47248
dc.language.isoeng
dc.publisherELSEVIER ESPANAeng
dc.relation.ispartofClinics
dc.rightsopenAccesseng
dc.rights.holderCopyright ELSEVIER ESPANAeng
dc.subjectThyroid neoplasmseng
dc.subjectIncidental findingseng
dc.subjectPathologyeng
dc.subjectDiagnosiseng
dc.subject.otherpapillary carcinomaeng
dc.subject.otherguidelineseng
dc.subject.otherexperienceeng
dc.subject.othermanagementeng
dc.subject.othernoduleseng
dc.subject.othercancereng
dc.subject.otherserieseng
dc.subject.otherriskeng
dc.subject.wosDermatologyeng
dc.titleIncidental thyroid carcinoma: Correlation between FNAB cytology and pathological examination in 1093 caseseng
dc.typearticleeng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng
dspace.entity.typePublication
hcfmusp.author.externalMOSCA, Leticia de Moraes:Univ Sao Paulo, Dept Cirurgia Cirurgia Cabeca & Pescoco, Fac Med FMUSP, Sao Paulo, SP, Brazil
hcfmusp.citation.scopus3
hcfmusp.contributor.author-fmusphcMARIANA GONCALVES RODRIGUES
hcfmusp.contributor.author-fmusphcLUIZ FERNANDO FERRAZ DA SILVA
hcfmusp.contributor.author-fmusphcVERGILIUS JOSE FURTADO DE ARAUJO FILHO
hcfmusp.contributor.author-fmusphcVERGILIUS JOSE FURTADO DE ARAUJO NETO
hcfmusp.contributor.author-fmusphcLUIZ PAULO KOWALSKI
hcfmusp.contributor.author-fmusphcPAULO CAMPOS CARNEIRO
hcfmusp.description.articlenumber100022
hcfmusp.description.volume77
hcfmusp.origemWOS
hcfmusp.origem.pubmed35306374
hcfmusp.origem.scieloSCIELO:S1807-59322022000100213
hcfmusp.origem.scopus2-s2.0-85126645035
hcfmusp.origem.wosWOS:000792713600002
hcfmusp.publisher.cityMADRIDeng
hcfmusp.publisher.countrySPAINeng
hcfmusp.relation.referenceAlshathry AH, 2020, CUREUS, V12, DOI 10.7759/cureus.11820eng
hcfmusp.relation.referenceBomeli SR, 2010, OTOLARYNG CLIN N AM, V43, P229, DOI 10.1016/j.otc.2010.01.002eng
hcfmusp.relation.referenceBradly DP, 2009, SURGERY, V146, P1099, DOI 10.1016/j.surg.2009.09.025eng
hcfmusp.relation.referenceChristakis I, 2018, ANN ROY COLL SURG, V100, P357, DOI 10.1308/rcsann.2018.0017eng
hcfmusp.relation.referenceCibas ES, 2009, AM J CLIN PATHOL, V132, P658, DOI 10.1309/AJCPPHLWMI3JV4LAeng
hcfmusp.relation.referenceEvranos B, 2019, DIAGN CYTOPATHOL, V47, P412, DOI 10.1002/dc.24117eng
hcfmusp.relation.referenceHARACH HR, 1985, CANCER-AM CANCER SOC, V56, P531, DOI 10.1002/1097-0142(19850801)56:3<531::AID-CNCR2820560321>3.0.CO;2-3eng
hcfmusp.relation.referenceHaugen BR, 2017, CANCER-AM CANCER SOC, V123, P372, DOI 10.1002/cncr.30360eng
hcfmusp.relation.referenceKaliszewski K, 2016, PLOS ONE, V11, DOI 10.1371/journal.pone.0168654eng
hcfmusp.relation.referenceKent WDT, 2007, CAN MED ASSOC J, V177, P1357, DOI 10.1503/cmaj.061730eng
hcfmusp.relation.referenceLin YS, 2016, Medicine (Baltimore), V95, P4194eng
hcfmusp.relation.referenceMachala E, 2018, POL J SURG, V90, P13, DOI 10.5604/01.3001.0012.4712eng
hcfmusp.relation.referenceMaturo A, 2017, G CHIR, V38, P94, DOI 10.11138/gchir/2017.38.2.094eng
hcfmusp.relation.referenceMiccoli P, 2006, ANZ J SURG, V76, P123, DOI 10.1111/j.1445-2197.2006.03667.xeng
hcfmusp.relation.referenceMolinaro E, 2021, EUR J ENDOCRINOL, V185, pR23, DOI 10.1530/EJE-21-0256eng
hcfmusp.relation.referenceMosca L, 2018, CLINICS, V73, DOI 10.6061/clinics/2018/e370eng
hcfmusp.relation.referencePagni F, 2014, ENDOCR PATHOL, V25, P288, DOI 10.1007/s12022-014-9323-xeng
hcfmusp.relation.referencePapini E, 2002, J CLIN ENDOCR METAB, V87, P1941, DOI 10.1210/jc.87.5.1941eng
hcfmusp.relation.referencePezzolla A, 2018, ANN ITAL CHIR, V89, P113eng
hcfmusp.relation.referencePezzolla A, 2014, INT J SURG, V12, pS98, DOI 10.1016/j.ijsu.2014.05.041eng
hcfmusp.relation.referencePopoveniuc G, 2012, MED CLIN N AM, V96, P329, DOI 10.1016/j.mcna.2012.02.002eng
hcfmusp.relation.referenceRahman M M, 2017, Mymensingh Med J, V26, P569eng
hcfmusp.relation.referenceSenel F, 2019, INDIAN J PATHOL MICR, V62, P211, DOI 10.4103/IJPM.IJPM_439_18eng
hcfmusp.relation.referenceSmith JJ, 2013, J AM COLL SURGEONS, V216, P571, DOI 10.1016/j.jamcollsurg.2012.12.022eng
hcfmusp.scopus.lastupdate2024-06-16
relation.isAuthorOfPublicationae5f6406-1a75-4d9a-81c2-20164fa5adcd
relation.isAuthorOfPublication0d4c5e63-ea43-4e35-9812-ff30ff292ef7
relation.isAuthorOfPublicationd65e3dc2-a997-4345-94c3-b1adc1cf2d81
relation.isAuthorOfPublication8434ce8e-9944-4533-8db7-9b8c26fe6241
relation.isAuthorOfPublication591f15eb-0938-4816-985a-42c5bb53ebed
relation.isAuthorOfPublication1198110b-044e-40bf-b543-2e8d3d58db72
relation.isAuthorOfPublication.latestForDiscoveryae5f6406-1a75-4d9a-81c2-20164fa5adcd
Arquivos
Pacote Original
Agora exibindo 1 - 1 de 1
Carregando...
Imagem de Miniatura
Nome:
art_RODRIGUES_Incidental_thyroid_carcinoma_Correlation_between_FNAB_cytology_and_2022.PDF
Tamanho:
1.09 MB
Formato:
Adobe Portable Document Format
Descrição:
publishedVersion (English)