Does a bilateral polypropylene mesh alter the duct deferens morphology, testicular size and testosterone levels? Experimental study in rats

dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorDAMOUS, Sergio Henrique Bastos
dc.contributor.authorDAMOUS, Luciana Lamarao
dc.contributor.authorMIRANDA, Jocielle dos Santos
dc.contributor.authorMONTERO, Edna Frasson de Souza
dc.contributor.authorBIROLINI, Claudio
dc.contributor.authorUTIYAMA, Edivaldo Massazo
dc.date.accessioned2020-06-01T14:46:00Z
dc.date.available2020-06-01T14:46:00Z
dc.date.issued2020
dc.description.abstractPurpose: To evaluate the effect of a PP mesh on duct deferens morphology, testicular size and testosterone levels. Methods: Forty adult male rats were distributed into groups: 1) no surgery; 2) inguinotomy; 3) mesh placed on the duct deferens; and 4) mesh placed on the spermatic funiculus. After 90 postoperative days, the inguinal region was resected, and blood samples were collected for the measurement of serum testosterone (pg/dl). The ducts deferens were sectioned in three axial sections according to the relationship with the mesh - cranial, medial and caudal. The wall thickness and duct deferens lumen area were measured. Results: The morphology of the duct deferens was preserved in all groups. The mesh placement did not alter this morphology in any of the analyzed segments. Surgery, with or without mesh placement, did not alter the morphology, wall thickness or lumen area (p>0.05). In all operated groups, serum testosterone levels were similar (p>0.05) but there was a decrease in testicle size (p<0.05). Conclusion: Surgery, with or without mesh placement, did not alter the morphology of the duct deferens and, although this treatment resulted in testicular size reduction, it did not affect serum testosterone levels.eng
dc.description.indexMEDLINEeng
dc.identifier.citationACTA CIRURGICA BRASILEIRA, v.35, n.2, article ID e202000201, 9p, 2020
dc.identifier.doi10.1590/s0102-865020200020000001
dc.identifier.eissn1678-2674
dc.identifier.issn0102-8650
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/35801
dc.language.isoeng
dc.publisherACTA CIRURGICA BRASILEIRAeng
dc.relation.ispartofActa Cirurgica Brasileira
dc.rightsopenAccesseng
dc.rights.holderCopyright ACTA CIRURGICA BRASILEIRAeng
dc.subjectHerniaeng
dc.subjectSurgical Mesheng
dc.subjectPolypropyleneseng
dc.subjectVas Deferenseng
dc.subjectTestiseng
dc.subjectRatseng
dc.subject.otherspermatic cord structureseng
dc.subject.otheringuinal-hernia repaireng
dc.subject.othervas-deferenseng
dc.subject.otherbioprosthesiseng
dc.subject.otherhernioplastyeng
dc.subject.otherobstructioneng
dc.subject.wosSurgeryeng
dc.titleDoes a bilateral polypropylene mesh alter the duct deferens morphology, testicular size and testosterone levels? Experimental study in ratseng
dc.typearticleeng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng
dspace.entity.typePublication
hcfmusp.author.externalMONTERO, Edna Frasson de Souza:Univ Fed Sao Paulo, Surg Gastroenterol Div, Dept Surg, Sao Paulo, SP, Brazil
hcfmusp.citation.scopus1
hcfmusp.contributor.author-fmusphcSERGIO HENRIQUE BASTOS DAMOUS
hcfmusp.contributor.author-fmusphcLUCIANA LAMARAO DAMOUS
hcfmusp.contributor.author-fmusphcJOCIELLE SANTOS DE MIRANDA
hcfmusp.contributor.author-fmusphcCLAUDIO AUGUSTO VIANNA BIROLINI
hcfmusp.contributor.author-fmusphcEDIVALDO MASSAZO UTIYAMA
hcfmusp.description.articlenumbere202000201
hcfmusp.description.issue2
hcfmusp.description.volume35
hcfmusp.origemWOS
hcfmusp.origem.pubmed32320995
hcfmusp.origem.scieloSCIELO:S0102-86502020000200206
hcfmusp.origem.scieloSCIELO:S0102-86502020000200202
hcfmusp.origem.scopus2-s2.0-85083949773
hcfmusp.origem.wosWOS:000529343200001
hcfmusp.publisher.citySAO PAULOeng
hcfmusp.publisher.countryBRAZILeng
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hcfmusp.scopus.lastupdate2024-06-09
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