Can preprocedural mouthrinses reduce SARS-CoV-2 load in dental aerosols?

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Citações na Scopus
22
Tipo de produção
article
Data de publicação
2021
Título da Revista
ISSN da Revista
Título do Volume
Editora
CHURCHILL LIVINGSTONE
Autores
REIS, Isabella Neme Ribeiro
AMARAL, Guilherme Castro Lima Silva do
MENDOZA, Aldrin Andre Huaman
GRACAS, Yasmin Teixeira das
ROMITO, Giuseppe Alexandre
PANNUTI, Claudio Mendes
Citação
MEDICAL HYPOTHESES, v.146, article ID 110436, 7p, 2021
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Dental professionals work closely with patients and present an increased risk of person-to-person transmission of SARS-CoV-2. Moreover, the use of ultrasonic scalers, air-water syringes, and slow and high-speed handpieces, which are common in the dental office, generate spatter and aerosol. The use of preprocedural mouthrinses has been proposed to reduce the viral load in saliva and oropharyngeal tissues, thus decreasing viral load in dental aerosol. Although some mouthrinses demonstrates an antiviral effect, there is limited evidence about the clinical efficacy of any mouthrinse in the reduction of SARS-CoV-2 in the dental aerosol. We hypothesized that mouthrinses may reduce SARS-CoV-2 viral load in the oropharynx and its fluids reducing viral load in dental aerosol. The potential use of mouthrinses is discussed, along with proposal of in vitro and clinical studies, in order to evaluate this hypothesis. If this hypothesis holds true, dental professionals and patients may benefit from the routine use of preprocedural mouthrinses.
Palavras-chave
Coronavirus, Covid-19, SARS-CoV-2, Mouthrinses, Mouthwashes, Aerosol
Referências
  1. Abd-Elghaffar AA, 2016, VACCINE, V34, P798, DOI 10.1016/j.vaccine.2015.12.041
  2. Abdallah Claude, 2015, J Anaesthesiol Clin Pharmacol, V31, P152, DOI 10.4103/0970-9185.155140
  3. American Dental Association (ADA), INT GUID MIN RISK CO
  4. American Dental Association (ADA), OR HLTH TOP MOUTHW M
  5. Ammerman Nicole C, 2008, Curr Protoc Microbiol, VAppendix 4, p4E, DOI 10.1002/9780471729259.mca04es11
  6. Baqui AAMA, 2001, J CLIN PERIODONTOL, V28, P610, DOI 10.1034/j.1600-051x.2001.028007610.x
  7. Basrani B, 2002, ORAL SURG ORAL MED O, V94, P240, DOI 10.1067/moe.2002.124002
  8. BERNSTEIN D, 1990, J DENT RES, V69, P874, DOI 10.1177/00220345900690030901
  9. Bidra AS, 2020, J PROSTHODONT, V29, P599, DOI 10.1111/jopr.13220
  10. Bidra AS, 2020, J PROSTHODONT, V29, P529, DOI 10.1111/jopr.13209
  11. Block SS, 1991, DISINFECTION STERILI, V4, P167
  12. BONESVOLL P, 1974, ARCH ORAL BIOL, V19, P209, DOI 10.1016/0003-9969(74)90263-5
  13. Brandao GC, 2010, PHYTOMEDICINE, V17, P926, DOI 10.1016/j.phymed.2010.03.004
  14. Caruso Arturo Armone, 2020, Med Hypotheses, V144, P109910, DOI 10.1016/j.mehy.2020.109910
  15. Castle PE, 2007, CANCER EPIDEM BIOMAR, V16, P840, DOI 10.1158/1055-9965.EPI-06-0909
  16. Center for Disease Control and Prevention, 2020, GUID DENT SETT INT I
  17. Chen LL, 2020, CELL PROLIFERAT, V53, DOI 10.1111/cpr.12923
  18. Chin AWH, 2020, LANCET MICROBE, V1, pE10, DOI 10.1016/S2666-5247(20)30003-3
  19. CROUGHAN WS, 1988, J CLIN MICROBIOL, V26, P213, DOI 10.1128/JCM.26.2.213-215.1988
  20. Dembinski JL, 2014, J VIROL METHODS, V207, P232, DOI 10.1016/j.jviromet.2014.07.003
  21. DENNISON DK, 1995, ORAL SURG ORAL MED O, V79, P442, DOI 10.1016/S1079-2104(05)80124-6
  22. DRAKE DR, 1993, J DENT RES, V72, P524, DOI 10.1177/00220345930720020901
  23. Eggers M, 2018, INFECT DIS THER, V7, P249, DOI 10.1007/s40121-018-0200-7
  24. Gerba CP, 2015, APPL ENVIRON MICROB, V81, P464, DOI 10.1128/AEM.02633-14
  25. Gottsauner MJ, 2020, CLIN ORAL INVEST, V24, P3707, DOI 10.1007/s00784-020-03549-1
  26. Grundemann LJMM, 2000, J CLIN PERIODONTOL, V27, P9, DOI 10.1034/j.1600-051x.2000.027001009.x
  27. GRYTTEN J, 1988, ACTA ODONTOL SCAND, V46, P181, DOI 10.3109/00016358809004765
  28. Harcourt Jennifer, 2020, bioRxiv, DOI 10.1101/2020.03.02.972935
  29. Jackson RJ, 1997, PERIODONTOL 2000, V15, P63, DOI 10.1111/j.1600-0757.1997.tb00106.x
  30. James P, 2017, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD008676.pub2
  31. Kampf G, 2020, J HOSP INFECT, V104, P246, DOI 10.1016/j.jhin.2020.01.022
  32. Khan MM, 2020, AM J OTOLARYNG, V41, DOI 10.1016/j.amjoto.2020.102618
  33. KRAUS F. W., 1958, ORAL SURG ORAL MED AND ORAL PATHOL, V11, P95, DOI 10.1016/0030-4220(58)90228-7
  34. Kumar PS, 2020, J PERIODONTOL, V91, P1113, DOI 10.1002/JPER.20-0395
  35. Lachenmeier DW, 2019, SIDE EFFECT, P251, DOI 10.1016/bs.seda.2019.07.005
  36. Lennette EH, 1979, DIAGNOSTIC PROCEDURE
  37. Liu CX, 2020, CHIN HERB MED, V12, P97, DOI 10.1016/j.chmed.2020.03.004
  38. Loizzo MR, 2008, CHEM BIODIVERS, V5, P461, DOI 10.1002/cbdv.200890045
  39. Lamas LM, 2020, ORAL DIS, DOI 10.1111/odi.13526
  40. Marui VC, 2019, J AM DENT ASSOC, V150, P1015, DOI 10.1016/j.adaj.2019.06.024
  41. McDonnell G, 1999, CLIN MICROBIOL REV, V12, P147, DOI 10.1128/CMR.12.1.147
  42. Meister TL, 2020, J INFECT DIS, V222, P1289, DOI 10.1093/infdis/jiaa471
  43. Mellier TF, 2005, J CLIN PERIODONTOL, V32, P341, DOI 10.1111/j.1600-051X.2005.00673.x
  44. Meng L, 2020, J DENT RES, V99, P481, DOI 10.1177/0022034520914246
  45. Mirhadi Hosein, 2014, Dent Res J (Isfahan), V11, P645
  46. Mukherjee PK, 2017, BMC INFECT DIS, V17, DOI 10.1186/s12879-016-2177-8
  47. Narayana T V, 2016, J Oral Maxillofac Pathol, V20, P59, DOI 10.4103/0973-029X.180931
  48. Olson AS, 2019, J EMERG MED, V56, P405, DOI 10.1016/j.jemermed.2018.12.026
  49. Omidbakhsh N, 2006, AM J INFECT CONTROL, V34, P251, DOI 10.1016/j.ajic.2005.06.002
  50. Patton LL, 2016, OR SURG OR MED OR PA, V121, P29, DOI 10.1016/j.oooo.2015.09.004
  51. Peng X, 2020, INT J ORAL SCI, V12, DOI 10.1038/s41368-020-0075-9
  52. Perlman S, 2009, NAT REV MICROBIOL, V7, P439, DOI 10.1038/nrmicro2147
  53. Popkin DL, 2017, PATHOGENS IMMUNITY, V2, P253, DOI 10.20411/PAI.V2I2.200
  54. Rosenthal S, 2004, ORAL SURG ORAL MED O, V98, P488, DOI 10.1016/j.tripleo.2003.07.005
  55. SCHMALZLE R, 2020, FUNCTION, V14, DOI 10.3389/FNHUM.2020.565772
  56. Seneviratne CJ, 2020, EFFICACY COMMERCIAL, DOI [10.1101/2020.09.14.20186494, DOI 10.1101/2020.09.14.20186494]
  57. Sharp G, 2016, ANZ J SURG, V86, P237, DOI 10.1111/ans.13269
  58. Steinberg D, 1999, J ORAL REHABIL, V26, P151, DOI 10.1046/j.1365-2842.1999.00343.x
  59. Stoopler Eric T, 2013, J Calif Dent Assoc, V41, P259
  60. Tartaglia GM, 2019, THER ADV DRUG SAF, V10, DOI 10.1177/2042098619854881
  61. Tay MZ, 2020, NAT REV IMMUNOL, V20, P363, DOI 10.1038/s41577-020-0311-8
  62. Teng F, 2016, INT J ORAL SCI, V8, P182, DOI 10.1038/ijos.2016.18
  63. To KKW, 2020, LANCET INFECT DIS, V20, P565, DOI 10.1016/S1473-3099(20)30196-1
  64. van Doremalen N, 2020, NEW ENGL J MED, V382, P1564, DOI 10.1056/NEJMc2004973
  65. Vlachojannis C, 2013, PHYTOTHER RES, V27, P685, DOI 10.1002/ptr.4762
  66. Walsh KA, 2020, J INFECTION, V81, P357, DOI 10.1016/j.jinf.2020.06.067
  67. Walsh LJ, 2000, AUST DENT J, V45, P257, DOI 10.1111/j.1834-7819.2000.tb00261.x
  68. Wolfel R, 2020, NATURE, V588, pE35, DOI [10.1159/000505601, 10.1038/s41586-020-2984-3, 10.1038/s41586-020-2196-x]
  69. World Health Organization, 2020, TRANSMISSION SARS CO
  70. World Health Organization, 2020, EB VIR DIS DEM REP C, P1
  71. World Health Organization, 2020, TIM WHOS RESP COVID
  72. Xu H, 2020, INT J ORAL SCI, V12, DOI 10.1038/s41368-020-0074-x
  73. Xu ZQ, 2011, AEROSOL SCI TECH, V45, P1337, DOI 10.1080/02786826.2011.593591
  74. Yoon JG, 2020, J KOREAN MED SCI, V35, DOI 10.3346/jkms.2020.35.e195
  75. Zou LR, 2020, NEW ENGL J MED, V382, P1177, DOI 10.1056/NEJMc2001737