Departamento de Clínica Médica - FM/MCM

O Departamento de Clínica Médica da Faculdade de Medicina da Universidade de São Paulo (FMUSP) iniciou-se em 1917 quando o Dr. Domingos Rubião Alves Meira tornou-se, por decreto, Professor Catedrático da 1ª Clínica Médica; na ocasião, a estrutura do Departamento hoje conhecida não estava formulada, portanto, é importante ter em conta que desta data até os dias atuais muitas sucessões e mudanças estruturais foram implementadas no Departamento de Clínica Médica.

Como resultado do histórico que liga o Departamento de Clínica Médica às origens da Faculdade de Medicina da Universidade de São Paulo e, em decorrência dos avanços obtidos no decorrer de sua existência, ele atua hoje como um dos maiores departamento da Faculdade com 43 docentes distribuídos em dez Disciplinas: Reumatologia; Imunologia Clínica e Alergia; Clínica Geral e Propedêutica; Emergências Clínicas; Serviço de Geriatria; Endocrinologia e Metabologia; Unidade de Endocrinologia Genética/Hereditária; Hematologia e Hemoterapia; Nefrologia e Terapêutica Clínica.

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Recent Submissions

  1. Data-driven, cross-disciplinary collaboration: lessons learned at the largest academic health center in Latin America during the COVID-19 pandemic

    FRONTIERS IN PUBLIC HEALTH, v.12, article ID 1369129, 15p, 2024

    Introduction The COVID-19 pandemic has prompted global research efforts to reduce infection impact, highlighting the potential of cross-disciplinary collaboration to enhance research quality and efficiency.Methods At the FMUSP-HC academic health system, we implemented innovative flow management r...

  2. A single session of aerobic exercise reduces systolic blood pressure at rest and in response to stress in women with rheumatoid arthritis and hypertension

    JOURNAL OF HUMAN HYPERTENSION, v.38, n.2, p.168-176, 2024

    Rheumatoid arthritis (RA) is an autoimmune inflammatory disease characterized by increased risk of cardiovascular disease and hypertension (HT). A single session of aerobic exercise may reduce blood pressure (BP) in different clinical groups; however, little is known about the acute effects of ex...

  3. The Prolonged Activation of the p65 Subunit of the NF-Kappa-B Nuclear Factor Sustains the Persistent Effect of Advanced Glycation End Products on Inflammatory Sensitization in Macrophages

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.25, n.5, article ID 2713, 16p, 2024

    Advanced glycation end products (AGEs) prime macrophages for lipopolysaccharide (LPS)-induced inflammation. We investigated the persistence of cellular AGE-sensitization to LPS, considering the nuclear content of p50 and p65 nuclear factor kappa B (NFKB) subunits and the expression of inflammator...

  4. How Do You Treat <i>Spinal Stenosis</i> <i>in the Geriatric Population</i> in Your Practice?

    MEDICAL ACUPUNCTURE, v.35, n.1, p.51-56, 2023

  5. Prevalence and clinical consequences of Hepatitis C virus infection in patients undergoing hematopoietic stem cell transplantation


    Hepatitis C virus (HCV) infection is a significant cause of morbidity and mortality among hematopoietic stem cell transplant (HCT) recipients. In Brazil, its occurrence in HCT recipients remains undetermined. We now report on HCV prevalence in HCT recipients and its clinical consequences. The med...

  6. Genomic landscapes of ovarian clear cell carcinoma from latin countries reveal aberrations linked to survival and progression

    BMC CANCER, v.23, n.1, article ID 613, 13p, 2023

    BackgroundOvarian clear cell carcinomas (OCCCs) are rare, aggressive and chemoresistant tumors. Geographical and ethnic differences in the incidence of OCCC have been reported with a higher incidence in Asiatic countries. There is a paucity of information regarding OCCC in Latin America (LA) and ...

  7. Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic

    LANCET, v.398, n.10312, p.1700-1712, 2021

    Background Before 2020, mental disorders were leading causes of the global health-related burden, with depressive and anxiety disorders being leading contributors to this burden. The emergence of the COVID-19 pandemic has created an environment where many determinants of poor mental health are ex...

  8. Measurement of uncertainty tolerance revisited

    CLINICAL TEACHER, v.20, n.6, 2023

    IntroductionUncertainty tolerance (UT) is attracting increasing attention in medical education due to the numerous challenges associated with uncertainty in professional life. Inconsistencies in analysing the relationship between UT and moderators may arise from inadequate measurement methods. Mo...

  9. Soluble MICA in endometriosis pathophysiology: Impairs NK cell degranulation and effector functions

    AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, v.91, n.3, article ID e13830, 15p, 2024

    Problem: Endometriosis exhibits several immune dysfunctions, including deficient natural killer (NK) cell cytotoxicity. MICA (MHC class I chain-related molecule A) is induced by biological stress and soluble MICA (sMICA) negatively modulates the expression of the activating receptor, NKG2D, reduc...

  10. Global Burden of Cardiovascular Diseases and Risks, 1990-2022

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, v.82, n.25, p.2350-2473, 2023