Departamento de Clínica Médica - FM/MCM

O Departamento de Clínica Médica da Faculdade de Medicina da Universidade de São Paulo (FMUSP) iniciou-se em 1917 quando o Dr. Domingos Rubião Alves Meira tornou-se, por decreto, Professor Catedrático da 1ª Clínica Médica; na ocasião, a estrutura do Departamento hoje conhecida não estava formulada, portanto, é importante ter em conta que desta data até os dias atuais muitas sucessões e mudanças estruturais foram implementadas no Departamento de Clínica Médica.

Como resultado do histórico que liga o Departamento de Clínica Médica às origens da Faculdade de Medicina da Universidade de São Paulo e, em decorrência dos avanços obtidos no decorrer de sua existência, ele atua hoje como um dos maiores departamento da Faculdade com 43 docentes distribuídos em dez Disciplinas: Reumatologia; Imunologia Clínica e Alergia; Clínica Geral e Propedêutica; Emergências Clínicas; Serviço de Geriatria; Endocrinologia e Metabologia; Unidade de Endocrinologia Genética/Hereditária; Hematologia e Hemoterapia; Nefrologia e Terapêutica Clínica.

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Recent Submissions

  1. Effects of Oxysterols on Immune Cells and Related Diseases

    CELLS, v.11, n.8, article ID 1251, 26p, 2022

    Oxysterols are the products of cholesterol oxidation. They have a wide range of effects on several cells, organs, and systems in the body. Oxysterols also have an influence on the physiology of the immune system, from immune cell maturation and migration to innate and humoral immune responses. In...

  2. Risk of osteoporotic fracture in women using the FRAX tool with and without bone mineral density score in patients followed at a tertiary outpatient clinic-An observational study

    CLINICS, v.77, article ID 100015, 5p, 2022

    Objectives: Fragility fractures increase morbidity and mortality. Adding assessment of clinical risk factors independently or as a previous step to Bone Densitometry (BD) should provide better accuracy in fracture risk prediction. FRAX tool might be used to stratify patients in order to rationali...

  3. Coronary calcification and bone microarchitecture by high-resolution peripheral quantitative computed tomography from the Sao Paulo Ageing and Health (SPAH) Study

    SCIENTIFIC REPORTS, v.12, n.1, article ID 5282, 11p, 2022

    Epidemiological studies reveal a link between osteoporosis and the risk of ischemic cardiovascular disease. We illustrate an association between coronary calcification and bone microarchitecture in older adults based on the SPAH study. This cross-sectional research comprised 256 individuals subje...

  4. Phenformin increases early hematopoietic progenitors in the Jak2(V617F) murine model

    INVESTIGATIONAL NEW DRUGS, v.40, n.3, p.576-585, 2022

    Background. Myeloproliferative neoplasms (MPN) are disorders characterized by an alteration at the hematopoietic stem cell (HSC) level, where the JAK2 mutation is the most common genetic alteration found in classic MPN (polycythemia vera, essential thrombocythemia, and primary myelofibrosis). We ...

  5. Clinical features of hereditary angioedema and warning signs (H4AE) for its identification

    CLINICS, v.77, article ID 100023, 4p, 2022

    Objectives: The study describes a case series of hereditary angioedema with C1 Inhibitor Deficiency (C1INH-HAE) in order to corroborate six clinical warning signs ""HAAAAE (H4AE)"" to enable early identification of this disease. Methods: The authors analyzed the C1INH-HAE cohort to analyze the cl...

  6. Spatial, temporal, and demographic patterns in prevalence of chewing tobacco use in 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019

    LANCET PUBLIC HEALTH, v.6, n.7, p.E482-E499, 2021

    Interpretation Chewing tobacco remains a substantial public health problem in several regions of the world, and predominantly in south Asia. We found little change in the prevalence of chewing tobacco use between 1990 and 2019, and that control efforts have had much larger effects on the prevalen...

  7. Is work-family conflict a pathway between job strain components and binge eating? A cross-sectional analysis from the ELSA-Brasil study

    JOURNAL OF EATING DISORDERS, v.10, n.1, article ID 16, 9p, 2022

    Background Job strain has been reported as a trigger for binge eating, yet the underlying mechanisms have been unclear. The aim of this study was to evaluate whether work-family conflict is a pathway in the association between job strain and binge eating, considering the possible effect-modifying...

  8. Temporal Reduction in COVID-19-Associated Fatality Among Kidney Transplant Recipients: The Brazilian COVID-19 Registry Cohort Study

    TRANSPLANT INTERNATIONAL, v.36, article ID 10205, 11p, 2022

    Data from the general population suggest that fatality rates declined during the course of the pandemic. This analysis, using data extracted from the Brazilian Kidney Transplant COVID-19 Registry, seeks to determine fatality rates over time since the index case on March 3rd, 2020. Data from hospi...

  9. Associations of cognitive performance with cardiovascular magnetic resonance phenotypes in the UK Biobank


    Aims Existing evidence suggests links between brain and cardiovascular health. We investigated associations between cognitive performance and cardiovascular magnetic resonance (CMR) phenotypes in the UK Biobank, considering a range of potential confounders. Methods and results We studied 29 763 p...

  10. Airway inflammatory profile among cleaning workers from different workplaces

    BMC PULMONARY MEDICINE, v.22, n.1, article ID 170, 12p, 2022

    Background Cleaning workers represent a significant proportion of the active population worldwide, with poor remuneration, particularly in developing countries. Despite this, they remain a relatively poorly studied occupational group. They are constantly exposed to agents that can cause symptoms ...