• Effects of combined theta burst stimulation and transcranial direct current stimulation of the dorsolateral prefrontal cortex on stress 

  SMET, Stefanie De; BAEKEN, Chris; RAEDT, Rudi De; PULOPULOS, Matias M.; RAZZA, Lais B.; DAMME, Stefaan Van; WITTE, Sara De; BRUNONI, Andre R.; VANDERHASSELT, Marie-Anne (ELSEVIER IRELAND LTD, CLARE, IRELAND, 2021)

  Objective: Research suggests that the combination of different non-invasive brain stimulation techniques, such as intermittent theta-burst stimulation (iTBS) and transcranial direct current stimulation (tDCS), could enhance ...
• Effects of continuous positive airway pressure on depression and anxiety symptoms in patients with obstructive sleep apnoea: results from the sleep apnoea cardiovascular Endpoint randomised trial and meta-analysis 

  ZHENG, Danni; XU, Ying; YOU, Shoujiang; HACKETT, Maree L.; WOODMAN, Richard J.; LI, Qiang; WOODWARD, Mark; LOFFLER, Kelly A.; RODGERS, Anthony; DRAGER, Luciano F.; LORENZI-FILHO, Geraldo; WANG, Xia; QUAN, Wei Wei; TRIPATHI, Manjari; MEDIANO, Olga; OU, Qiong; CHEN, Rui; LIU, Zhihong; ZHANG, Xilong; LUO, Yuanming; MCARDLE, Nigel; MUKHERJEE, Sutapa; MCEVOY, R. Douglas; ANDERSON, Craig S. (ELSEVIER, AMSTERDAM, NETHERLANDS, 2019)

  Background: Whether continuous positive airway pressure (CPAP) treatment can improve depression or anxiety symptoms in obstructive sleep apnoea (OSA) patients remains uncertain. Methods: Secondary analysis of the Sleep ...
• Kinetics of Muscle Carnosine Decay after beta-Alanine Supplementation: A 16-wk Washout Study 

  YAMAGUCHI, Guilherme Carvalho; NEMEZIO, Kleiner; SCHULZ, Mariane Leichsenring; NATALI, Jose; CESAR, Jonatas Eduardo; RIANI, Luiz Augusto; GONCALVES, Livia De Souza; MOLLER, Gabriella Berwig; SALE, Craig; MEDEIROS, Marisa Helena Gennari De; GUALANO, Bruno; ARTIOLI, Guilherme Giannini (LIPPINCOTT WILLIAMS & WILKINS, PHILADELPHIA, USA, 2021)

  Purpose This study aimed to describe the kinetics of carnosine washout in human skeletal muscle over 16 wk. Methods Carnosine washout kinetics were studied in 15 young, physically active omnivorous men randomly assigned ...
• Prognostic assessment for chronic myelomonocytic leukemia in the context of the World Health Organization 2016 proposal: a multicenter study of 280 patients 

  GONZALEZ, Jacqueline S.; PERUSINI, Maria Agustina; BASQUIERA, Ana L.; ALFONSO, Graciela; FANTL, Dorotea; LIMA, Walter Macedo; NUCIFORA, Elsa; LAZZARINO, Carolina; NOVOA, Viviana; SILVA, Marcela Cavalcanti de Andrade; LARRIPA, Irene B.; ROCHA, Vanderson; ARBELBIDE, Jorge; VELLOSO, Elvira D. R. P.; BELLI, Carolina B. (SPRINGER, NEW YORK, UNITED STATES, 2021)

  Knowledge on chronic myelomonocytic leukemia (CMML) patients from Argentina and Brazil is limited. Our series of 280 patients depicted an older age at diagnosis (median 72 years old), 26% of aberrant karyotypes, and a ...
• Association of Carotid Plaques and Common Carotid Intima-media Thickness with Modifiable Cardiovascular Risk Factors 

  SANTOS-NETO, Pedro J.; SENA-SANTOS, Eduardo H.; MEIRELES, Danilo P.; BITTENCOURT, Marcio Sommer; SANTOS, Itamar S.; BENSENOR, Isabela M.; LOTUFO, Paulo A. (ELSEVIER, AMSTERDAM, NETHERLANDS, 2021)

  Objective: To assess the association of carotid plaques and common carotid artery intimamedia thickness with traditional modifiable cardiovascular risk factors. Methods: We examined 4,266 participants aged 35-74years in ...
• Cohort Profile: The Cohorts Consortium of Latin America and the Caribbean (CC-LAC) 

  CARRILLO-LARCO, Rodrigo M.; CESARE, Mariachiara Di; HAMBLETON, Ian R.; HENNIS, Anselm; IRAZOLA, Vilma; STERN, Dalia; FERRECCIO, Catterina; LOTUFO, Paulo; PEREL, Pablo; GREGG, Edward W.; EZZATI, Majid; DANAEI, Goodarz; MIRANDA, J. Jaime; AGUILAR-SALINAS, Carlos A.; ALVAREZ-VAZ, Ramon; AMADIO, Marselle B.; BACCINO, Cecilia; BAMBS, Claudia; BASTOS, Joao Luiz; BECKLES, Gloria; BERNABE-ORTIZ, Antonio; BERNARDO, Carla D. O.; BLOCH, Katia V.; BLUMEL, Juan E.; BOGGIA, Jose G.; BORGES, Pollyanna K.; BRAVO, Miguel; BRENES-CAMACHO, Gilbert; CARBAJAL, Horacio A.; RASCON, Maria S. Castillo; CEBALLOS, Blanca H.; COLPANI, Veronica; CONFORTIN, Susana C.; COOPER, Jackie A.; CORTES-VALENCIA, Adrian; CORTES, Sandra; CUNHA, Roberto S.; D'ORSI, Eleonora; DOW, William H.; ESPECHE, Walter G.; FUCHS, Flavio D.; FUCHS, Sandra C.; GIMENO, Suely G. A.; GOMEZ-VELASCO, Donaji; GONZALEZ-VILLALPANDO, Clicerio; GONZALEZ-VILLALPANDO, Maria-Elena; GONZALEZ-CHICA, David A.; GRAZIOLI, Gonzalo; GUERRA, Ricardo O.; GUTIERREZ, Laura; HERKENHOFF, Fernando L.; HORIMOTO, Andrea R. V. R.; HUIDOBRO, Andrea; KOCH, Elard; LAJOUS, Martin; LIMA-COSTA, Maria Fernanda; LOPEZ-RIDAURA, Ruy; MACIEL, Alvaro C. C.; MANRIQUE-ESPINOZA, Betty S.; MARQUES, Larissa P.; MILL, Jose G.; MOREIRA, Leila B.; ONO, Lariane M.; MUNOZ, Oscar M.; OPPERMANN, Karen; PEIXOTO, Sergio V.; PEREIRA, Alexandre C.; PERES, Karen G.; PERES, Marco A.; RODRIGUEZ, Nohora I.; ROJAS-MARTINEZ, Rosalba; ROSERO-BIXBY, Luis; RUBINSTEIN, Adolfo; RUIZ-MORALES, Alvaro; SALAZAR, Martin R.; SALINAS-RODRIGUEZ, Aaron; SANCHEZ, Ramon A.; SCHNEIDER, Ione J. C.; SILVA, Thiago L. N.; SILVA, Nelson A. S.; SMEETH, Liam; SPRITZER, Poli M.; TARTAGLIONE, Fiorella; TARTAGLIONE, Jorge (OXFORD UNIV PRESS, OXFORD, ENGLAND, 2020)
• Is there an association between upper limb claudication and handgrip strength in Takayasu arteritis? 

  SANTOS, A. M. dos; MISSE, R. G.; BORGES, I. B. P.; PEREIRA, R. M. R.; SHINJO, S. K. (PAGEPRESS PUBL, PAVIA, ITALY, 2020)

  Limb vascular claudication and hand muscle weakness are common symptoms of Takayasu arteritis (TAK). However, no studies have correlated these two symptoms. Therefore, the aim of the study was to evaluate handgrip strength ...
• 7-Ketocholesterol and cholestane-triol increase expression of SMO and LXR alpha signaling pathways in a human breast cancer cell line 

  LEVY, Debora; MELO, Thatiana Correa de; OLIVEIRA, Beatriz A.; PAZ, Jessica L.; FREITAS, Fabio A. de; REICHERT, Cadiele O.; RODRIGUES, Alessandro; BYDLOWSKI, Sergio P. (ELSEVIER, AMSTERDAM, NETHERLANDS, 2019)

  Oxysterols are 27-carbon oxidation products of cholesterol metabolism. Oxysterols possess several biological actions, including the promotion of cell death. Here, we examined the ability of 7-ketocholesterol (7-KC), ...
• New Approaches for the Treatment of Chagas Disease 

  PANDEY, Ramendra Pati; NASCIMENTO, Marilda Savoia; MOORE, Catrin E.; RAJ, V. Samuel; KALIL, Jorge; CUNHA-NETO, Edecio (BENTHAM SCIENCE PUBL LTD, SHARJAH, U ARAB EMIRATES, 2021)

  Chagas disease, caused by the protozoan Trypanosoma cruzi is a neglected tropical disease with high prevalence (5.7 million in Latin America, WHO 2015), significant burden, and significant morbimortality mostly due to ...
• First-attempt intubation success and complications in patients with COVID-19 undergoing emergency intubation 

  ALENCAR, Julio Cesar Garcia de; MARQUES, Bruno; MARCHINI, Julio Flavio Meirelles; MARINO, Lucas Oliveira; RIBEIRO, Sabrina Correa da Costa; BUENO, Caue Gasparotto; CUNHA, Victor Paro da; LAZAR NETO, Felippe; VALENTE, Fernando Salvetti; RAHHAL, Hassan; PEREIRA, Juliana Batista Rodrigues; PADRAO, Eduardo Messias Hirano; WANDERLEY, Annelise Passos Bispos; COSTA, Millena Gomes Pinheiro; BRANDAO NETO, Rodrigo Antonio; SOUZA, Heraldo Possolo (WILEY, HOBOKEN, USA, 2020)

  ObjectivesTo evaluate the first-attempt success rates and complications of endotracheal intubation of coronavirus disease 2019 (COVID-19) patients by emergency physicians. MethodsThis prospective observational study was ...
• Common and specific aspects of anxiety and depression and the metabolic syndrome 

  HOFFMANN, Mauricio Scopel; BRUNONI, Andre Russowsky; STRINGARIS, Argyris; VIANA, Maria Carmen; LOTUFO, Paulo Andrade; BENSENOR, Isabela Martins; SALUM, Giovanni Abrahao (PERGAMON-ELSEVIER SCIENCE LTD, OXFORD, ENGLAND, 2021)

  Introduction: The associations of anxiety and depression with metabolic syndrome (MetS) are not consistent across studies. Anxiety and depression are highly correlated and traditional methods don?t take the structure of ...
• NT157, an IGF1R-IRS1/2 inhibitor, exhibits antineoplastic effects in pre-clinical models of chronic myeloid leukemia 

  SCOPIM-RIBEIRO, Renata; MACHADO-NETO, Joao Agostinho; EIDE, Christopher A.; COELHO-SILVA, Juan Luiz; FENERICH, Bruna Alves; FERNANDES, Jaqueline Cristina; SCHEUCHER, Priscila Santos; STEVENS, Samantha L. Savage; CAMPOS, Paula de Melo; SAAD, Sara T. Olalla; PALMA, Leonardo de Carvalho; FIGUEIREDO-PONTES, Lorena Lobo de; SIMOES, Belinda Pinto; REGO, Eduardo Magalhaes; TOGNON, Cristina E.; DRUKER, Brian J.; TRAINA, Fabiola (SPRINGER, DORDRECHT, NETHERLANDS, 2021)

  Chronic myeloid leukemia (CML) is successfully treated with BCR-ABL1 tyrosine kinase inhibitors, but a significant percentage of patients develop resistance. Insulin receptor substrate 1 (IRS1) has been shown to constitutively ...
• Molecular-Based Score inspired on metabolic signature improves prognostic stratification for myelodysplastic syndrome 

  COELHO-SILVA, Juan L.; SILVEIRA, Douglas R. A.; PEREIRA-MARTINS, Diego A.; ROJAS, Cesar A. O.; LUCENA-ARAUJO, Antonio R.; REGO, Eduardo M.; MACHADO-NETO, Joao A.; BENDIT, Israel; ROCHA, Vanderson; TRAINA, Fabiola (NATURE RESEARCH, BERLIN, GERMANY, 2021)

  Deregulated cellular energetics is formally incorporated as an emerging hallmark of cancer, however little is known about its processes in myelodysplastic syndromes (MDS). Using transcriptomic data of CD34+ cells from 159 ...
• Obstructive sleep apnea and ambulatory blood pressure monitoring: current evidence and research gaps 

  PIO-ABREU, Andrea; MORENO JR., Heitor; DRAGER, Luciano F. (SPRINGERNATURE, LONDON, ENGLAND, 2021)

  Obstructive Sleep Apnea (OSA) is a common condition characterized by intermittent collapse of the upper airway during sleep, resulting in partial (hypopnoeas) and total obstructions (apneas). These respiratory events ...
• Correlation between SARS-COV-2 antibody screening by immunoassay and neutralizing antibody testing 

  MENDRONE-JUNIOR, Alfredo; DINARDO, Carla Luana; FERREIRA, Suzete Cleuza; NISHYA, Anna; SALLES, Nanci Alves; ALMEIDA NETO, Cesar de; HAMASAKI, Debora Toshei; FACINCANI, Tila; ALVES, Lucas Bassolli de Oliveira; MACHADO, Rafael Rahal Guaragna; ARAUJO, Danielle Bastos; DURIGON, Edison Luiz; ROCHA, Vanderson; SABINO, Ester Cerdeira (WILEY, HOBOKEN, USA, 2021)

  Background The efficacy of convalescent plasma (CP), an alternative for the treatment of COVID-19, depends on high titers of neutralizing antibodies (nAbs), but assays for quantifying nAbs are not widely available. Our ...
• The role of VES-13 to identify limited life expectancy in older adults in primary healthcare settings 

  ASSIS, Danilo Lopes; CHAGAS, Virginia Oliveira; SAULO, Helton; SUEMOTO, Claudia Kimie; SANTANA, Alfredo Nicodemos Cruz (UNIV SAO PAOLO, CERQUERA CESAR, BRAZIL, 2021)

  Objective: To investigate the potential role of the Vulnerable Elders Survey to identify older adults with limited life expectancy in primary healthcare settings. Method: This cross-sectional study was performed in all ...
• Assistance and health care provided to adolescents with chronic and immunosuppressive conditions in a tertiary university hospital during the COVID-19 pandemic 

  LAVORATO, Sofia S. M.; HELITO, Alberto C.; BARROS, Vera P. M. F. R.; ROZ, Deborah F. P.; SACCANI, Ligia P.; MARTINIANO, Lorena V. M.; LIMA, Livia M. L.; LIMA, Dandara C. C.; LOURENCO, Benito; PEREIRA, Rosa M. R.; GUALANO, Bruno; SILVA, Clovis A.; QUEIROZ, Ligia B. (HOSPITAL CLINICAS, UNIV SAO PAULO, SAO PAULO, BRAZIL, 2021)
• A longitudinal multiethnic study of biomarkers in systemic lupus erythematosus: Launching the GLADEL 2.0 Study Group 

  GOMEZ-PUERTA, Jose A.; PONS-ESTEL, Guillermo J.; QUINTANA, Rosana; NIETO, Romina; MORALES, Rosa M. Serrano; HARVEY, Guillermina B.; WOJDYLA, Daniel; SCOLNIK, Marina; SOAJE, Carmen Funes; MOREYRA, Paula Alba; NOVATTI, Elisa; ARIZPE, Fernando; BERBOTTO, Guillermo A.; LUCERO, Luciana Gonzalez; PORTA, Sabrina; PEREZ, Nicolas; RODRIGUEZ, Anabella M.; APPENZELLER, Simone; MONTADON, Ana Carolina de Oliveira e Silva; MONTICIELO, Odirlei Andre; CAVALCANTI, Fernando S.; RIBEIRO, Francinne Machado; BORBA, Eduardo F.; REIS-NETO, Edgard Torres dos; NEIRA, Oscar; CHAHUAN, Jose Miguel; MIMICA, Milena; MARTINEZ, Gustavo Aroca; TOBON, Gabriel J.; VASQUEZ, Gloria; QUINTANA-LOPEZ, Gerardo; ALVAREZ, Mario J. Moreno; SAAVEDRA, Miguel Angel; CRISTOBAL, Mario Perez; FRAGOSO-LOYO, Hilda; AMEZCUA-GUERRA, Luis M.; GONZALEZ-BELLO, Yelitza C.; ABUD-MENDOZA, Carlos; ESQUIVEL-VALERIO, Jorge A.; DUARTE, Margarita; COLMAN, Isabel Acosta; MORA-TRUJILLO, Claudia; REATEGUI-SOKOLOVA, Cristina; QUIROZ, Armando A. Calvo; MUNOZ-LOUIS, Roberto; CAIROLI, Ernesto; ROSAS, Iliana; REBELLA, Martin; CARDIEL, Mario H.; TORRE, Ignacio Garcia de la; CATOGGIO, Luis J.; ALARCON, Graciela S.; PONS-ESTEL, Bernardo A. (SAGE PUBLICATIONS LTD, LONDON, ENGLAND, 2021)

  Introduction: After more than 20 years of sustained work, the Latin American Group for the Study of Lupus (GLADEL) has made a significant number of contributions to the field of lupus, not only in the differential role ...
• NLRP3 and NLRP1 inflammasomes are up-regulated in patients with mesial temporal lobe epilepsy and may contribute to overexpression of caspase-1 and IL-beta in sclerotic hippocampi 

  TOSCANO, Eliana Cristina de Brito; VIEIRA, Erica Leandro Marciano; DIAS, Barbara Boni Rocha; CALIARI, Marcelo Vidigal; GONCALVES, Ana Paula; GIANNETTI, Alexandre Varela; SIQUEIRA, Jose Mauricio; SUEMOTO, Claudia Kimie; LEITE, Renata Elaine Paraizo; NITRINI, Ricardo; RACHID, Milene Alvarenga; TEIXEIRA, Antonio Lucio (ELSEVIER, AMSTERDAM, NETHERLANDS, 2021)

  Inflammation plays a role in the pathophysiology of mesial temporal lobe epilepsy (MLLE). Inflammasome pathways, including the NLRP1 and NLRP3-induced ones, promote neuroinflammation and pyroptosis through interleukin ...
• Short Dietary Intervention with Olive Oil Increases Brown Adipose Tissue Activity in Lean but not Overweight Subjects 

  MONFORT-PIRES, Milena; U-DIN, Mueez; NOGUEIRA, Guilherme A.; ALMEIDA-FARIA, Juliana de; SIDARTA-OLIVEIRA, Davi; SANT'ANA, Marcella Ramos; LIMA-JUNIOR, Jose C. de; CINTRA, Dennys E.; SOUZA, Heraldo Possolo de; FERREIRA, Sandra R. G.; SAPIENZA, Marcelo Tatit; VIRTANEN, Kirsi A.; VELLOSO, Licio A. (ENDOCRINE SOC, WASHINGTON, USA, 2021)

  Background: The brown adipose tissue (BAT) is a potential target for the treatment of obesity and metabolic disorders. Its activation by cold exposure or adrenergic drugs can increase systemic insulin sensitivity and improve ...

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