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https://observatorio.fm.usp.br/handle/OPI/1194Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor | Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP | - |
| dc.contributor.author | SARTORELLI, Patricia | - |
| dc.contributor.author | SANTANA, Jefferson S. | - |
| dc.contributor.author | GUADAGNIN, Rafael C. | - |
| dc.contributor.author | LAGO, Joao Henrique G. | - |
| dc.contributor.author | PINTO, Erika G. | - |
| dc.contributor.author | TEMPONE, Andre G. | - |
| dc.contributor.author | STEFANI, Helio A. | - |
| dc.contributor.author | SOARES, Marisi G. | - |
| dc.contributor.author | SILVA, Adalberto M. da | - |
| dc.date.accessioned | 2013-07-30T15:32:33Z | - |
| dc.date.available | 2013-07-30T15:32:33Z | - |
| dc.date.issued | 2012 | - |
| dc.identifier.citation | QUIMICA NOVA, v.35, n.4, p.743-747, 2012 | - |
| dc.identifier.issn | 0100-4042 | - |
| dc.identifier.uri | https://observatorio.fm.usp.br/handle/OPI/1194 | - |
| dc.description.abstract | Essential oils of ripe fruits from Schinus terebinthifolius (Anacardiaceae), obtained using a pilot extractor and a Clevenger apparatus were chemically characterized. Due the high amount of (-)-alpha-pinene in both oils, this monoterpene was tested against the protozoan parasite Trypanosoma cruzi, showing a moderate potential (IC50 63.56 mu g/mL) when compared to benznidazole (IC50 43.14 mu g/mL). Otherwise, (-)-alpha-pinene oxide did not showed anti-trypanosomal activity (IC50 > 400 mu g/mL) while (-)-pinane showed an IC50 of 56.50 mu g/mL. The obtained results indicated that the epoxydation of a-pinene results to the loss of the anti-parasitic activity while its hydrogenation product, contributed slightly to the increased activity. | - |
| dc.description.sponsorship | FAPESP | - |
| dc.description.sponsorship | CNPq | - |
| dc.language.iso | eng | - |
| dc.publisher | SOC BRASILEIRA QUIMICA | - |
| dc.relation.ispartof | Quimica Nova | - |
| dc.rights | openAccess | - |
| dc.subject | Schinus terebinthifolius Raddi | - |
| dc.subject | Anacardiaceae | - |
| dc.subject | trypanocidal activity | - |
| dc.subject.other | chemical-composition | - |
| dc.subject.other | leaves | - |
| dc.subject.other | monoterpenes | - |
| dc.subject.other | berries | - |
| dc.title | IN VITRO TRYPANOCIDAL EVALUATION OF PINANE DERIVATIVES FROM ESSENTIAL OILS OF RIPE FRUITS FROM Schinus terebinthifolius RADDI (ANACARDIACEAE) | - |
| dc.type | article | - |
| dc.rights.holder | Copyright SOC BRASILEIRA QUIMICA | - |
| dc.identifier.doi | 10.1590/S0100-40422012000400017 | - |
| dc.subject.wos | Chemistry, Multidisciplinary | - |
| dc.type.category | original article | - |
| dc.type.version | publishedVersion | - |
| hcfmusp.author.external | SARTORELLI, Patricia:Univ Fed Sao Paulo, Inst Ciencias Ambientais Quim & Farmaceut, BR-09972279 Diadema, SP, Brazil | - |
| hcfmusp.author.external | SANTANA, Jefferson S.:Univ Fed Sao Paulo, Inst Ciencias Ambientais Quim & Farmaceut, BR-09972279 Diadema, SP, Brazil | - |
| hcfmusp.author.external | GUADAGNIN, Rafael C.:Univ Fed Sao Paulo, Inst Ciencias Ambientais Quim & Farmaceut, BR-09972279 Diadema, SP, Brazil | - |
| hcfmusp.author.external | LAGO, Joao Henrique G.:Univ Fed Sao Paulo, Inst Ciencias Ambientais Quim & Farmaceut, BR-09972279 Diadema, SP, Brazil | - |
| hcfmusp.author.external | TEMPONE, Andre G.:Adolfo Lutz Inst, Dept Parasitol, BR-01246000 Sao Paulo, Brazil | - |
| hcfmusp.author.external | STEFANI, Helio A.:Univ Sao Paulo, Fac Ciencias Farmaceut, Dept Farm, BR-05508000 Sao Paulo, Brazil | - |
| hcfmusp.author.external | SOARES, Marisi G.:Univ Fed Alfenas, Inst Quim, BR-37130000 Alfenas, MG, Brazil | - |
| hcfmusp.author.external | SILVA, Adalberto M. da:Univ Fed Vicosa, Dept Quim, BR-36570000 Vicosa, MG, Brazil | - |
| hcfmusp.description.beginpage | 743 | - |
| hcfmusp.description.endpage | 747 | - |
| hcfmusp.description.issue | 4 | - |
| hcfmusp.description.volume | 35 | - |
| hcfmusp.origem | WOS | - |
| hcfmusp.origem.id | 2-s2.0-84862892188 | - |
| hcfmusp.origem.id | WOS:000304226400017 | - |
| hcfmusp.publisher.city | SAO PAULO | - |
| hcfmusp.publisher.country | BRAZIL | - |
| hcfmusp.relation.reference | Adams R.R, 1995, IDENTIFICATION ESSEN | - |
| hcfmusp.relation.reference | Barbosa L. C. A., 2007, Quimica Nova, V30, P1959, DOI 10.1590/S0100-40422007000800030 | - |
| hcfmusp.relation.reference | Bazhenov YP, 2003, RUSS J APPL CHEM, V76, P232 | - |
| hcfmusp.relation.reference | Campello J. P., 1974, PHYTOCHEMISTRY, V13, P659, DOI 10.1016/S0031-9422(00)91376-1 | - |
| hcfmusp.relation.reference | Campello J. P., 1975, PHYTOCHEMISTRY, V14, P2300 | - |
| hcfmusp.relation.reference | Castro JM, 2005, TETRAHEDRON, V61, P11192, DOI 10.1016/j.tet.2005.09.023 | - |
| hcfmusp.relation.reference | Ceruks M, 2007, QUIM NOVA, V30, P597 | - |
| hcfmusp.relation.reference | Chowdhury A. R., 2001, IND PERFUM, V45, P257 | - |
| hcfmusp.relation.reference | Correa DS, 2011, PARASITOL RES, V109, P231, DOI 10.1007/s00436-010-2229-8 | - |
| hcfmusp.relation.reference | DAVIES NW, 1990, J CHROMATOGR, V503, P1, DOI 10.1016/S0021-9673(01)81487-4 | - |
| hcfmusp.relation.reference | Diaz C, 2008, NAT PROD RES, V22, P1521, DOI 10.1080/14786410701848154 | - |
| hcfmusp.relation.reference | Ibrahim M. T., 2004, B FACULTY PHARM, V42, P289 | - |
| hcfmusp.relation.reference | JAIN MK, 1995, PHYTOCHEMISTRY, V39, P537, DOI 10.1016/0031-9422(94)00960-2 | - |
| hcfmusp.relation.reference | Jamal Y., 2001, MAJALAH FARMASI INDO, V12, P135 | - |
| hcfmusp.relation.reference | Kubeczka K.-H., 2002, ESSENTIAL OILS ANAL | - |
| hcfmusp.relation.reference | Lago JHG, 2008, QUIM NOVA, V31, P727, DOI 10.1590/S0100-40422008000400002 | - |
| hcfmusp.relation.reference | Lago JHG, 2010, J BRAZIL CHEM SOC, V21, P1760, DOI 10.1590/S0103-50532010000900024 | - |
| hcfmusp.relation.reference | Lima MRF, 2006, J ETHNOPHARMACOL, V105, P137, DOI 10.1016/J.JEP.2005.10.026 | - |
| hcfmusp.relation.reference | LLOYD HA, 1977, PHYTOCHEMISTRY, V16, P1301, DOI 10.1016/S0031-9422(00)94384-X | - |
| hcfmusp.relation.reference | LORENZI H., 1992, ARVORES BRASILEIRAS | - |
| hcfmusp.relation.reference | Malik MS, 1994, SCI INT LAHORE, V6, P351 | - |
| hcfmusp.relation.reference | Medeiros K. C. P., 2007, Revista Brasileira de Farmacognosia, V17, P023, DOI 10.1590/S0102-695X2007000100006 | - |
| hcfmusp.relation.reference | Mesquita ML, 2009, J ETHNOPHARMACOL, V123, P439 | - |
| hcfmusp.relation.reference | MONEAM NMA, 1986, J CHROMATOGR, V361, P391, DOI 10.1016/S0021-9673(01)86931-4 | - |
| hcfmusp.relation.reference | MORTON JF, 1978, ECON BOT, V32, P353, DOI 10.1007/BF02907927 | - |
| hcfmusp.relation.reference | Pio-Correa M., 1984, DICIONARIO PLANTAS U | - |
| hcfmusp.relation.reference | Reimao JQ, 2010, BIOORGAN MED CHEM, V18, P8044, DOI 10.1016/j.bmc.2010.09.015 | - |
| hcfmusp.relation.reference | Ruffa MJ, 2002, J ETHNOPHARMACOL, V79, P335, DOI 10.1016/S0378-8741(01)00400-7 | - |
| hcfmusp.relation.reference | Saladino R, 2003, TETRAHEDRON, V59, P7403, DOI 10.1016/S0040-4020(03)01145-1 | - |
| hcfmusp.relation.reference | Schmourlo G, 2005, J ETHNOPHARMACOL, V96, P563, DOI 10.1016/j.pep.2004.10.007 | - |
| hcfmusp.relation.reference | Singh A. K., 1998, Journal of Essential Oil Research, V10, P697 | - |
| hcfmusp.relation.reference | Soares MG, 2010, QUIM NOVA, V33, P1141, DOI 10.1590/S0100-40422010000500026 | - |
| dc.description.index | PubMed | - |
| hcfmusp.remissive.sponsorship | CNPq | - |
| hcfmusp.remissive.sponsorship | FAPESP | - |
| hcfmusp.citation.scopus | 17 | - |
| hcfmusp.scopus.lastupdate | 2022-05-06 | - |
| Appears in Collections: | Artigos e Materiais de Revistas Científicas - IMT | |
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| art_PINTO_IN_VITRO_TRYPANOCIDAL_EVALUATION_OF_PINANE_DERIVATIVES_FROM_2012.PDF | publishedVersion (English) | 307.41 kB | Adobe PDF |  View/Open |
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