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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorSILVA, Cilene Saghabi de Medeiros-
dc.contributor.authorTIMENETSKY, Karina T.-
dc.contributor.authorTANIGUCHI, Corinne-
dc.contributor.authorCALEGARO, Sedila-
dc.contributor.authorAZEVEDO, Carolina Sant'Anna A.-
dc.contributor.authorSTUS, Ricardo-
dc.contributor.authorMATOS, Gustavo Faissol Janot de-
dc.contributor.authorEID, Raquel A. C.-
dc.contributor.authorBARBAS, Carmen Silvia Valente-
dc.identifier.citationCLINICS, v.67, n.9, p.995-1000, 2012-
dc.description.abstractOBJECTIVES: A number of complications exist with invasive mechanical ventilation and with the use of and withdrawal from prolonged ventilator support. The use of protocols that enable the systematic identification of patients eligible for an interruption in mechanical ventilation can significantly reduce the number of complications. This study describes the application of a weaning protocol and its results. METHODS: Patients who required invasive mechanical ventilation for more than 24 hours were included and assessed daily to identify individuals who were ready to begin the weaning process. RESULTS: We studied 252 patients with a median mechanical ventilation time of 3.7 days (interquartile range of 1 to 23 days), a rapid shallow breathing index value of 48 (median), a maximum inspiratory pressure of 40 cmH2O, and a maximum expiratory pressure of 40 cm H2O (median). Of these 252 patients, 32 (12.7%) had to be reintubated, which represented weaning failure. Noninvasive ventilation was used postextubation in 170 (73%) patients, and 15% of these patients were reintubated, which also represented weaning failure. The mortality rate of the 252 patients studied was 8.73% (22), and there was no significant difference in the age, gender, mechanical ventilation time, and maximum inspiratory pressure between the survivors and nonsurvivors. CONCLUSIONS: The use of a specific weaning protocol resulted in a lower mechanical ventilation time and an acceptable reintubation rate. This protocol can be used as a comparative index in hospitals to improve the weaning system, its monitoring and the informative reporting of patient outcomes and may represent a future tool and source of quality markers for patient care.-
dc.subjectVentilator weaning-
dc.subjectClinical protocols-
dc.subject.otherpositive-pressure ventilation-
dc.subject.othersupport ventilation-
dc.titleLow mechanical ventilation times and reintubation rates associated with a specific weaning protocol in an intensive care unit setting: a retrospective study-
dc.rights.holderCopyright HOSPITAL CLINICAS, UNIV SAO PAULO-
dc.subject.wosMedicine, General & Internal-
dc.type.categoryoriginal article-
dc.type.versionpublishedVersion-, Cilene Saghabi de Medeiros:Hosp Israelita Albert Einstein, Critically Patients Dept 3, Intens Care Unit, Sao Paulo, Brazil-, Karina T.:Hosp Israelita Albert Einstein, Critically Patients Dept 3, Intens Care Unit, Sao Paulo, Brazil-, Corinne:Hosp Israelita Albert Einstein, Critically Patients Dept 3, Intens Care Unit, Sao Paulo, Brazil-, Sedila:Hosp Israelita Albert Einstein, Critically Patients Dept 3, Intens Care Unit, Sao Paulo, Brazil-, Carolina Sant'Anna A.:Hosp Israelita Albert Einstein, Critically Patients Dept 3, Intens Care Unit, Sao Paulo, Brazil-, Ricardo:Hosp Israelita Albert Einstein, Critically Patients Dept 3, Intens Care Unit, Sao Paulo, Brazil-, Gustavo Faissol Janot de:Hosp Israelita Albert Einstein, Critically Patients Dept 3, Intens Care Unit, Sao Paulo, Brazil-, Raquel A. C.:Hosp Israelita Albert Einstein, Critically Patients Dept 3, Intens Care Unit, Sao Paulo, Brazil-
hcfmusp.publisher.citySAO PAULO-
hcfmusp.relation.referenceAmbrosino N, 2008, EUR RESPIR J, V31, P874, DOI 10.1183/09031936.00143507-
hcfmusp.relation.referenceBrook AD, 1999, CRIT CARE MED, V27, P2609, DOI 10.1097/00003246-199912000-00001-
hcfmusp.relation.referenceBurns KEA, 2006, CAN J ANAESTH, V53, P305-
hcfmusp.relation.referenceDe Bast Y, 2002, INTENS CARE MED, V28, P1267, DOI 10.1007/s00134-002-1422-3-
hcfmusp.relation.referenceEly EW, 1996, NEW ENGL J MED, V335, P1864, DOI 10.1056/NEJM199612193352502-
hcfmusp.relation.referenceEpstein SK, 1998, AM J RESP CRIT CARE, V158, P489-
hcfmusp.relation.referenceEpstein SK, 2006, PRINCIPLES PRACTICE, P877-
hcfmusp.relation.referenceEpstein SK, 1997, CHEST, V112, P186, DOI 10.1378/chest.112.1.186-
hcfmusp.relation.referenceEsteban A, 2004, NEW ENGL J MED, V350, P2452, DOI 10.1056/NEJMoa032736-
hcfmusp.relation.referenceEsteban A, 1997, AM J RESP CRIT CARE, V156, P459-
hcfmusp.relation.referenceEsteban A, 2002, JAMA-J AM MED ASSOC, V287, P345, DOI 10.1001/jama.287.3.345-
hcfmusp.relation.referenceGil B, 2003, CLIN PULM MED, V10, P226, DOI 10.1097/01.cpm.0000080906.11193.b5-
hcfmusp.relation.referenceGoldwasser R, 2007, REV BRAS TER INTENSI, V19, P384-
hcfmusp.relation.referenceHorst HM, 1998, ARCH SURG-CHICAGO, V133, P483, DOI 10.1001/archsurg.133.5.483-
hcfmusp.relation.referenceKollef MH, 1998, CHEST, V114, P541, DOI 10.1378/chest.114.2.541-
hcfmusp.relation.referenceKollef MH, 1997, CRIT CARE MED, V25, P567, DOI 10.1097/00003246-199704000-00004-
hcfmusp.relation.referenceKress JP, 2000, NEW ENGL J MED, V342, P1471, DOI 10.1056/NEJM200005183422002-
hcfmusp.relation.referenceKrishnan JA, 2004, AM J RESP CRIT CARE, V169, P673, DOI 10.1164/rccm.200306-7610C-
hcfmusp.relation.referenceMacIntyre N, 2007, CHEST, V132, P1049, DOI 10.1378/chest.06-2862-
hcfmusp.relation.referenceMarelich GP, 2000, CHEST, V118, P459, DOI 10.1378/chest.118.2.459-
hcfmusp.relation.referenceRothaar Robert C, 2003, Curr Opin Crit Care, V9, P59, DOI 10.1097/00075198-200302000-00011-
hcfmusp.relation.referenceVargas F, 2008, J CRIT CARE, V23, P577, DOI 10.1016/j.jcrc.2007.12.009-
hcfmusp.relation.referenceVitacca M, 2001, AM J RESP CRIT CARE, V164, P638-
hcfmusp.relation.referenceWeavind L, 2000, J CLIN MONITOR COMP, V16, P409, DOI 10.1023/A:1011480409161-
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