Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/1387
Title: Parent psychopathology and offspring mental disorders: results from the WHO World Mental Health Surveys
Authors: MCLAUGHLIN, Katie A.GADERMANN, Anne M.HWANG, IrvingSAMPSON, Nancy A.AL-HAMZAWI, AliANDRADE, Laura HelenaANGERMEYER, Matthias C.BENJET, CorinaBROMET, Evelyn J.BRUFFAERTS, RonnyCALDAS-DE-ALMEIDA, Jose MiguelGIROLAMO, Giovanni deGRAAF, Ron deFLORESCU, SilviaGUREJE, OyeHARO, Josep MariaHINKOV, Hristo RuskovHORIGUCHI, ItsukoHU, ChiyiKARAM, Aimee NasserKOVESS-MASFETY, VivianeLEE, SingMURPHY, Samuel D.NIZAMIE, S. HaquePOSADA-VILLA, JoseWILLIAMS, David R.KESSLER, Ronald C.
Citation: BRITISH JOURNAL OF PSYCHIATRY, v.200, n.4, p.290-299, 2012
Abstract: Background Associations between specific parent and offspring mental disorders are likely to have been overestimated in studies that have failed to control for parent comorbidity. Aims To examine the associations of parent with respondent disorders. Method Data come from the World Health Organization (WHO) World Mental Health Surveys (n = 51 507). Respondent disorders were assessed with the Composite International Diagnostic Interview and parent disorders with informant-based Family History Research Diagnostic Criteria interviews. Results Although virtually all parent disorders examined (major depressive, generalised anxiety, panic, substance and antisocial behaviour disorders and suicidality) were significantly associated with offspring disorders in multivariate analyses, little specificity was found. Comorbid parent disorders had significant sub-additive associations with offspring disorders. Population-attributable risk proportions for parent disorders were 12.4% across all offspring disorders, generally higher in high- and upper-middle-than low-/lower-middle-income countries, and consistently higher for behaviour (11.0-19.9%) than other (7.1-14.0%) disorders. Conclusions Parent psychopathology is a robust non-specific predictor associated with a substantial proportion of offspring disorders.
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Artigos e Materiais de Revistas Científicas - LIM/23

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