Mechanisms of Corneal Pain and Implications for Postoperative Pain After Laser Correction of Refractive Errors

Show simple item record

dc.contributor Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.author GARCIA, Renato FMUSP-HC
ANDRADE, Daniel C. de FMUSP-HC
TEIXEIRA, Manoel J. FMUSP-HC
NOZAKI, Siro S. FMUSP-HC
BECHARA, Samir J. FMUSP-HC
dc.date.issued 2016
dc.identifier.citation CLINICAL JOURNAL OF PAIN, v.32, n.5, p.450-458, 2016
dc.identifier.issn 0749-8047
dc.identifier.uri http://observatorio.fm.usp.br/handle/OPI/14282
dc.description.abstract Objective:The cornea is the target of most surgeries for refractive disorders, as myopia. It is estimated that almost 1 million patients undergo corneal refractive surgery each year in the United States. Refractive surgery includes photorefractive keratectomy (PRK) that produces intense postoperative pain. This review presents the main pain mechanisms behind PRK-related pain and the available therapeutic options for its management.Methods:Data sources included literature of cornea anatomy, treatment of PRK postoperative pain, mechanisms of corneal pain, in 3 electronic databases: Pubmed, Scopus, and Web of Science. Only double-blinded controlled trials on pain control after PRK were selected to show the endpoints, treatment, and control strategies.Results:A total of 18 double-blind, controlled trials were identified. These studies have shown the use of topical nonsteroidal anti-inflammatory drugs, topical steroidal anti-inflammatory drugs, systemic analgesics, cold balanced saline solution, topical anesthetic, gabapentin, and morphine to treat postoperative pain in PRK.Discussion:The percentage of responders has seldom been reported, and few studies allow for the formal calculation of the number necessary to treat. Postoperative intense pain after PRK laser surgery remains the main challenge to its widespread use for the correction of refractive errors.
dc.language.iso eng
dc.publisher LIPPINCOTT WILLIAMS & WILKINS
dc.relation.ispartof Clinical Journal of Pain
dc.rights restrictedAccess
dc.subject corneal; pain; photorefractive keratectomy; postoperative; laser
dc.subject.other in-situ keratomileusis; bilateral photorefractive keratectomy; 10-year follow-up; nonsteroidal antiinflammatory drugs; bandage contact-lenses; double-masked trial; ocular pain; topical diclofenac; than-6 diopters; oral gabapentin
dc.title Mechanisms of Corneal Pain and Implications for Postoperative Pain After Laser Correction of Refractive Errors
dc.type article
dc.rights.holder Copyright LIPPINCOTT WILLIAMS & WILKINS
dc.description.group LIM/26
dc.description.group LIM/33
dc.identifier.doi 10.1097/AJP.0000000000000271
dc.type.category review
dc.type.version publishedVersion
hcfmusp.author GARCIA, Renato:FM:
hcfmusp.author ANDRADE, Daniel C. de:HC:ICESP
hcfmusp.author TEIXEIRA, Manoel J.:FM:MNE
hcfmusp.author NOZAKI, Siro S.:HC:ICHC
hcfmusp.author BECHARA, Samir J.:HC:ICHC
hcfmusp.origem.id WOS:000374796700011
hcfmusp.origem.id 2-s2.0-84963682756
hcfmusp.publisher.city PHILADELPHIA
hcfmusp.publisher.country USA
hcfmusp.relation.reference · TERVO K, 1994, ARCH OPHTHALMOL-CHIC, V112, P1466
· PEYMAN GA, 1994, BRIT J OPHTHALMOL, V78, P138, DOI 10.1136/bjo.78.2.138
· Shaheen BS, 2014, SURV OPHTHALMOL, V59, P263, DOI 10.1016/j.survophthal.2013.09.002
· Caldwell M, 2008, J REFRACT SURG, V24, P377
· ROZSA AJ, 1982, PAIN, V14, P105, DOI 10.1016/0304-3959(82)90092-6
· Belmonte C, 2004, EXP EYE RES, V78, P513, DOI 10.1016/j.exer.2003.09.023
· Edwards JD, 2008, J CATARACT REFR SURG, V34, P1288, DOI 10.1016/j.jcrs.2008.04.024
· Solomon KD, 2004, J CATARACT REFR SURG, V30, P1653, DOI 10.1016/j.jcrs.2004.05.019
· Donnenfeld ED, 2007, ADV THER, V24, P852, DOI 10.1007/BF02849978
· Nakamura K, 2003, CORNEA, V22, pS35, DOI 10.1097/00003226-200310001-00006
· Zadok D, 2006, J CATARACT REFR SURG, V32, P117, DOI 10.1016/j.jcrs.2005.11.017
· PARK D, 1995, INVEST OPHTH VIS SCI, V36, pS39
· Ang EK, 2009, J CATARACT REFR SURG, V35, P921, DOI 10.1016/j.jcrs.2009.02.013
· Durrie DS, 2007, ADV THER, V24, P1278, DOI 10.1007/BF02877774
· Moreira LB, 1999, J CATARACT REFR SURG, V25, P975, DOI 10.1016/S0886-3350(99)00075-9
· Netto MV, 2006, J REFRACT SURG, V22, P562
· Gallar J, 2007, INVEST OPHTH VIS SCI, V48, P4033, DOI 10.1167/iovs.07-0012
· Colin J, 2006, CLIN THER, V28, P527, DOI 10.1016/j.clinthera.2006.04.004
· Erie JC, 2005, AM J OPHTHALMOL, V140, P1059, DOI 10.1016/j.ajo.2005.07.027
· Kanellopoulos AJ, 1997, J CATARACT REFR SURG, V23, P34
· Muller LJ, 2003, EXP EYE RES, V76, P521, DOI 10.1016/S0014-4835(03)00050-2
· Verma S, 1995, OPHTHALMOLOGY, V102, P1918
· Solomon KD, 2009, OPHTHALMOLOGY, V116, P691, DOI 10.1016/j.ophtha.2008.12.037
· Navas A, 2007, J REFRACT SURG, V23, P941
· Koshimizu J, 2010, GRAEF ARCH CLIN EXP, V248, P1817, DOI 10.1007/s00417-010-1312-2
· CHERRY PMH, 1994, J REFRACT CORNEAL S, V10, pS222
· Tutton MK, 1996, J CATARACT REFR SURG, V22, P536
· Kitazawa Y, 1999, J CATARACT REFR SURG, V25, P1349, DOI 10.1016/S0886-3350(99)00207-2
· van Wijk G, 2010, J PAIN, V11, P408, DOI 10.1016/j.jpain.2009.10.009
· BELMONTE C, 1981, J PHYSIOL-LONDON, V321, P355
· Nissman SA, 2008, AM J OPHTHALMOL, V145, P623, DOI 10.1016/j.ajo.2007.11.012
· Scholz J, 2007, NAT NEUROSCI, V10, P1361, DOI 10.1038/nn1992
· Shahinian L, 1997, OPHTHALMOLOGY, V104, P1327
· Acosta MC, 2005, INVEST OPHTH VIS SCI, V46, P282, DOI 10.1167/iovs.04-0884
· BERNS MW, 1988, OPHTHALMOLOGY, V95, P1422
· Kamiya K, 2009, CORNEA, V28, P765, DOI 10.1097/ICO.0b013e3181967082
· Verma S, 1996, INVEST OPHTH VIS SCI, V37, P919
· Kuhnle MD, 2011, J CATARACT REFR SURG, V37, P364, DOI 10.1016/j.jcrs.2010.08.041
· Engle AT, 2005, J CATARACT REFR SURG, V31, P681, DOI 10.1016/j.jcrs.2004.09.022
· STEIN R, 1994, AM J OPHTHALMOL, V117, P403
· McCarty CA, 1996, J REFRACT SURG, V12, P365
· HIRATA F, 1980, P NATL ACAD SCI-BIOL, V77, P2533, DOI 10.1073/pnas.77.5.2533
· Alio JL, 2008, AM J OPHTHALMOL, V145, P37, DOI 10.1016/j.ajo.2007.09.009
· Majmuder PA, 2000, OPHTHALMOLOGY, V107, P89, DOI 10.1016/S0161-6420(99)00019-6
· Mohammadpour M, 2011, J CATARACT REFR SURG, V37, P633, DOI 10.1016/j.jcrs.2010.10.040
· Hersh PS, 1998, OPHTHALMOLOGY, V105, P1512, DOI 10.1016/S0161-6420(98)98038-1
· Vetrugno M, 2000, OPHTHALMIC SURG LAS, V31, P400
· FLACH AJ, 1992, SURV OPHTHALMOL, V36, P259, DOI 10.1016/0039-6257(92)90095-B
· Gamulescu MA, 2005, J CATARACT REFR SURG, V31, P1255, DOI 10.1016/j.jcrs.2005.04.002
· Seiler T, 1998, J REFRACT SURG, V14, P312
· Wilson SE, 2001, ARCH OPHTHALMOL-CHIC, V119, P889
· Faktorovich EG, 2010, J REFRACT SURG, V26, P934, DOI 10.3928/1081597X-20100212-06
· El-Maghraby A, 1999, OPHTHALMOLOGY, V106, P447, DOI 10.1016/S0161-6420(99)90102-1
· DelMonte DW, 2011, J CATARACT REFR SURG, V37, P588, DOI 10.1016/j.jcrs.2010.12.037
· Erie JC, 2003, CORNEA, V22, P684, DOI 10.1097/00003226-200310000-00014
· Matsui H, 2001, J CATARACT REFR SURG, V27, P370, DOI 10.1016/S0886-3350(00)00756-2
· May A, 2002, CEPHALALGIA, V22, P195, DOI 10.1046/j.1468-2982.2002.00342.x
· Lichtinger A, 2011, J REFRACT SURG, V27, P613, DOI 10.3928/1081597X-20110210-01
· Vetrugno M, 2000, CLIN THER, V22, P719, DOI 10.1016/S0149-2918(00)90006-7
· Resnikoff S, 2004, B WORLD HEALTH ORGAN, V82, P844
· Belmonte C, 1997, PROG RETIN EYE RES, V16, P117, DOI 10.1016/S1350-9462(96)00027-4
· Alio JL, 2008, AM J OPHTHALMOL, V145, P29, DOI 10.1016/j.ajo.2007.09.007
· Arshinoff SA, 1996, J CATARACT REFR SURG, V22, P1037
· De Armentia ML, 2000, NEUROSCIENCE, V101, P1109
· MELZACK R, 1975, PAIN, V1, P277, DOI 10.1016/0304-3959(75)90044-5
· Hong JW, 2001, INVEST OPHTH VIS SCI, V42, P2795
· Vetrugno M, 2001, ACTA OPHTHALMOL SCAN, V79, P23, DOI 10.1034/j.1600-0420.2001.079001023.x
· Marfurt CF, 2010, EXP EYE RES, V90, P478, DOI 10.1016/j.exer.2009.12.010
· Derry CJ, 2012, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD009663
· Kempen AH, 2004, ARCH OPHTHALMOL-CHIC, V122, P495
· Pakravan M, 2012, EUR J OPHTHALMOL, V22, pS106, DOI [10.5301/ejo.5000143, 10.5301/00.5000143]
· Rad AS, 2004, J REFRACT SURG, V20, pS718
· Razmju Hassan, 2012, Int J Prev Med, V3, pS199
· Shortt AJ, 2013, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD005135.pub3
· STEIN C, 1995, NEW ENGL J MED, V332, P1685
· Sulivan MJL, 1995, PSYCHOL ASSESSMENT, V7, P524
· Toms L, 2008, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD004602.PUB2
· Verma S, 1997, Eur J Ophthalmol, V7, P327
dc.description.index MEDLINE
dc.identifier.eissn 1536-5409
hcfmusp.citation.scopus 4
hcfmusp.citation.wos 4


Files in this item

This item appears in the following Collection(s)

Show simple item record

Search DSpace



Browse

My Account

Statistics