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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorSANANES, Nicolas-
dc.contributor.authorRODO, Carlota-
dc.contributor.authorPEIRO, Jose Luis-
dc.contributor.authorBRITTO, Ingrid Schwach Werneck-
dc.contributor.authorSANGI-HAGHPEYKAR, Haleh-
dc.contributor.authorFAVRE, Romain-
dc.contributor.authorJOAL, Arnaud-
dc.contributor.authorGAUDINEAU, Adrien-
dc.contributor.authorSILVA, Marcos Marques da-
dc.contributor.authorTANNURI, Uenis-
dc.contributor.authorZUGAIB, Marcelo-
dc.contributor.authorCARRERAS, Elena-
dc.contributor.authorRUANO, Rodrigo-
dc.identifier.citationJOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, v.29, n.18, p.3030-3034, 2016-
dc.description.abstractObjective: To evaluate the independent association of fetal pulmonary response and prematurity to postnatal outcomes after fetal tracheal occlusion for congenital diaphragmatic hernia. Methods: Fetal pulmonary response, prematurity (537 weeks at delivery) and extreme prematurity (532 weeks at delivery) were evaluated and compared between survivors and non-survivors at 6 months of life. Multivariable analysis was conducted with generalized linear mixed models for variables significantly associated with survival in univariate analysis. Results: Eighty-four infants were included, of whom 40 survived (47.6%) and 44 died (52.4%). Univariate analysis demonstrated that survival was associated with greater lung response (p = 0.006), and the absence of extreme preterm delivery (p = 0.044). In multivariable analysis, greater pulmonary response after FETO was an independent predictor of survival (aOR 1.87, 95% CI 1.08-3.33, p = 0.023), whereas the presence of extreme prematurity was not statistically associated with mortality after controlling for fetal pulmonary response (aOR 0.52, 95% CI 0.12-2.30, p = 0.367). Conclusion: Fetal pulmonary response after FETO is the most important factor associated with survival, independently from the gestational age at delivery.-
dc.description.sponsorshipFULBRIGHT Franco-American Commission for Education Exchange [68141003]-
dc.description.sponsorshipFAPESP (Fundacao de Amparo a Pesquisa do Estado de Sao Paulo) [2013/12493-1]-
dc.publisherTAYLOR & FRANCIS LTD-
dc.relation.ispartofJournal of Maternal-Fetal & Neonatal Medicine-
dc.subjectCongenital diaphragmatic hernia-
dc.subjectfetal lung-
dc.subjectfetal surgery-
dc.subjectlung-to-head ratio-
dc.subject.otherpostnatal management-
dc.subject.otherstomach position-
dc.titlePrematurity and fetal lung response after tracheal occlusion in fetuses with severe congenital diaphragmatic hernia-
dc.rights.holderCopyright TAYLOR & FRANCIS LTD-
dc.subject.wosObstetrics & Gynecology-
dc.type.categoryoriginal article-
dc.type.versionpublishedVersion-, Nicolas:Baylor Coll Med, Dept Obstet & Gynecol, Texas Childrens Fetal Ctr, Houston, TX 77030 USA; HUS, CMCO, Serv Gynecol Obstet, Strasbourg, France-, Carlota:Hosp Univ Vall Dhebron, Fetal Surg Program, Barcelona, Spain-, Jose Luis:Hosp Univ Vall Dhebron, Fetal Surg Program, Barcelona, Spain-, Ingrid Schwach Werneck:Baylor Coll Med, Dept Obstet & Gynecol, Texas Childrens Fetal Ctr, Houston, TX 77030 USA-, Haleh:Baylor Coll Med, Dept Obstet & Gynecol, Texas Childrens Fetal Ctr, Houston, TX 77030 USA-, Romain:HUS, CMCO, Serv Gynecol Obstet, Strasbourg, France-, Arnaud:HUS, CMCO, Serv Gynecol Obstet, Strasbourg, France-, Adrien:HUS, CMCO, Serv Gynecol Obstet, Strasbourg, France-, Elena:HUS, CMCO, Serv Gynecol Obstet, Strasbourg, France-
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Appears in Collections:

Artigos e Materiais de Revistas Científicas - FM/MOG
Departamento de Obstetrícia e Ginecologia - FM/MOG

Artigos e Materiais de Revistas Científicas - FM/MPE
Departamento de Pediatria - FM/MPE

Artigos e Materiais de Revistas Científicas - HC/ICHC
Instituto Central - HC/ICHC

Artigos e Materiais de Revistas Científicas - HC/ICr
Instituto da Criança - HC/ICr

Artigos e Materiais de Revistas Científicas - LIM/30
LIM/30 - Laboratório de Investigação em Cirurgia Pediátrica

Artigos e Materiais de Revistas Científicas - LIM/57
LIM/57 - Laboratório de Fisiologia Obstétrica

Artigos e Materiais de Revistas Científicas - ODS/03
ODS/03 - Saúde e bem-estar

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