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https://observatorio.fm.usp.br/handle/OPI/1449
Título: | Dynamic Aerobic Exercise Induces Baroreflex Improvement in Diabetic Rats |
Autor(es): | JORGE, Luciana; PUREZA, Demilto Y. da; DIAS, Danielle da Silva; CONTI, Filipe Fernandes; IRIGOYEN, Maria-Claudia; ANGELIS, Katia De |
Parte de: | EXPERIMENTAL DIABETES RESEARCH, article ID 108680, 5p, 2012 |
Resumo: | The objective of the present study was to investigate the effects of an acute aerobic exercise on arterial pressure (AP), heart rate (HR), and baroreflex sensitivity (BRS) in STZ-induced diabetic rats. Male Wistar rats were divided into control (n = 8) and diabetic (n = 8) groups. AP, HR, and BRS, which were measured by tachycardic and bradycardic (BR) responses to AP changes, were evaluated at rest (R) and postexercise session (PE) on a treadmill. At rest, STZ diabetes induced AP and HR reductions, associated with BR impairment. Attenuation in resting diabetes-induced AP (R: 103 +/- 2 versus PE: 111 +/- 3 mmHg) and HR (R: 290 +/- 7 versus PE:328 +/- 10 bpm) reductions and BR dysfunction (R: -0.70 +/- 0.06 versus PE:-1.21 +/- 0.09 bpm/mmHg) was observed in the postexercise period. In conclusion, the hemodynamic and arterial baro-mediated control of circulation improvement in the postexercise period reinforces the role of exercise in the management of cardiovascular risk in diabetes. |
Aparece nas coleções: | Artigos e Materiais de Revistas Científicas - HC/InCor Artigos e Materiais de Revistas Científicas - LIM/59 |
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art_JORGE_Dynamic_Aerobic_Exercise_Induces_Baroreflex_Improvement_in_Diabetic_2012.PDF | publishedVersion (English) | 1.14 MB | Adobe PDF | Visualizar/Abrir |
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