Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/16104
Full metadata record
DC FieldValueLanguage
dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorCHOWDHURI, Susmita-
dc.contributor.authorQUAN, Stuart F.-
dc.contributor.authorALMEIDA, Fernanda-
dc.contributor.authorAYAPPA, Indu-
dc.contributor.authorBATOOL-ANWAR, Salma-
dc.contributor.authorBUDHIRAJA, Rohit-
dc.contributor.authorCRUSE, Peggy E.-
dc.contributor.authorDRAGER, Luciano F.-
dc.contributor.authorGRISS, Barbara-
dc.contributor.authorMARSHALL, Nathaniel-
dc.contributor.authorPATEL, Sanjay R.-
dc.contributor.authorPATIL, Susheel-
dc.contributor.authorKNIGHT, Shandra L.-
dc.contributor.authorROWLEY, James A.-
dc.contributor.authorSLYMAN, Alison-
dc.date.accessioned2016-10-17T16:35:37Z-
dc.date.available2016-10-17T16:35:37Z-
dc.date.issued2016-
dc.identifier.citationAMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, v.193, n.9, p.E37-E54, 2016-
dc.identifier.issn1073-449X-
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/16104-
dc.description.abstractBackground: Mild obstructive sleep apnea (OSA) is a highly prevalent disorder in adults; however, whether mild OSA has significant neurocognitive and cardiovascular complications is uncertain. Objectives: The specific goals of this Research Statement are to appraise the evidence regarding whether long-term adverse neurocognitive and cardiovascular outcomes are attributable to mild OSA in adults, evaluate whether or not treatment of mild OSA is effective at preventing or reducing these adverse neurocognitive and cardiovascular outcomes, delineate the key research gaps, and provide direction for future research agendas. Methods: Literature searches from multiple reference databases were performed using medical subject headings and text words for OSA in adults as well as by hand searches. Pragmatic systematic reviews of the relevant body of evidence were performed. Results: Studies were incongruent in their definitions of ""mild"" OSA. Data were inconsistent regarding the relationship between mild OSA and daytime sleepiness. However, treatment of mild OSA may improve sleepiness in patients who are sleepy at baseline and improve quality of life. There is limited or inconsistent evidence pertaining to the impact of therapy of mild OSA on neurocognition, mood, vehicle accidents, cardiovascular events, stroke, and arrhythmias. Conclusions: There is evidence that treatment of mild OSA in individuals who demonstrate subjective sleepiness may be beneficial. Treatment may also improve quality of life. Future research agendas should focus on clarifying the effect of mild OSA and impact of effective treatment on other neurocognitive and cardiovascular endpoints as detailed in the document.-
dc.description.sponsorshipATS-
dc.language.isoeng-
dc.publisherAMER THORACIC SOC-
dc.relation.ispartofAmerican Journal of Respiratory and Critical Care Medicine-
dc.rightsrestrictedAccess-
dc.subject.otherpositive airway pressure-
dc.subject.otherquality-of-life-
dc.subject.otherexcessive daytime sleepiness-
dc.subject.otherpopulation-based sample-
dc.subject.otherindependent risk-factor-
dc.subject.othercoronary-heart-disease-
dc.subject.othermotor-vehicle crash-
dc.subject.otherall-cause mortality-
dc.subject.otherlong-term efficacy-
dc.subject.otherfollow-up-
dc.titleAn Official American Thoracic Society Research Statement: Impact of Mild Obstructive Sleep Apnea in Adults-
dc.typearticle-
dc.rights.holderCopyright AMER THORACIC SOC-
dc.contributor.groupauthorATS Ad Hoc Comm Mild Obstructive-
dc.identifier.doi10.1164/rccm.201602-0361ST-
dc.identifier.pmid27128710-
dc.subject.wosCritical Care Medicine-
dc.subject.wosRespiratory System-
dc.type.categoryoriginal article-
dc.type.versionpublishedVersion-
hcfmusp.description.beginpageE37-
hcfmusp.description.endpageE54-
hcfmusp.description.issue9-
hcfmusp.description.volume193-
hcfmusp.origemWOS-
hcfmusp.origem.idWOS:000375118200001-
hcfmusp.origem.id2-s2.0-84988932548-
hcfmusp.publisher.cityNEW YORK-
hcfmusp.publisher.countryUSA-
hcfmusp.relation.referenceAbe H, 2010, HEART VESSELS, V25, P63, DOI 10.1007/s00380-009-1164-z-
hcfmusp.relation.referenceAgency for Healthcare Research and Quality, 2011, DIAGN TREATM OBSTR S-
hcfmusp.relation.referenceAgha MA, 2014, EGYPT J CHEST DIS TU, V63, P155-
hcfmusp.relation.referenceAmerican Academy of Sleep Medicine, 2014, INT CLASS SLEEP DIS-
hcfmusp.relation.referenceArzt M, 2005, AM J RESP CRIT CARE, V172, P1447, DOI 10.1164/rccm.200505-702OC-
hcfmusp.relation.referenceAvlonitou E, 2012, SLEEP BREATH, V16, P563, DOI 10.1007/s11325-011-0543-8-
hcfmusp.relation.referenceBack LJJ, 2009, LARYNGOSCOPE, V119, P1621, DOI 10.1002/lary.20562-
hcfmusp.relation.referenceBaldwin CM, 2001, SLEEP, V24, P96-
hcfmusp.relation.referenceBallester E, 1998, EUR RESPIR J, V11, P880, DOI 10.1183/09031936.98.11040880-
hcfmusp.relation.referenceBalsevicius T, 2012, SLEEP BREATH, V16, P835, DOI 10.1007/s11325-011-0584-z-
hcfmusp.relation.referenceBarnes M, 2004, AM J RESP CRIT CARE, V170, P656, DOI 10.1164/rccm.200311-1571OC-
hcfmusp.relation.referenceBatool-Anwar Salma, 2014, Nat Sci Sleep, V6, P65, DOI 10.2147/NSS.S53721-
hcfmusp.relation.referenceBEARPARK H, 1995, AM J RESP CRIT CARE, V151, P1459-
hcfmusp.relation.referenceBecker HF, 2003, CIRCULATION, V107, P68, DOI 10.1161/01.CIR.0000042706.47107.7A-
hcfmusp.relation.referenceBerry RB, 2012, AASM MANUAL SCORING-
hcfmusp.relation.referenceBerry RB, 2012, J CLIN SLEEP MED, V8, P597, DOI 10.5664/jcsm.2172-
hcfmusp.relation.referenceBixler EO, 1998, AM J RESP CRIT CARE, V157, P144-
hcfmusp.relation.referenceBixler EO, 2001, AM J RESP CRIT CARE, V163, P608-
hcfmusp.relation.referenceBixler EO, 2000, ARCH INTERN MED, V160, P2289, DOI 10.1001/archinte.160.15.2289-
hcfmusp.relation.referenceBrown Lee K, 2007, J Clin Sleep Med, V3, P259-
hcfmusp.relation.referenceBudhiraja R, 2005, SLEEP, V28, P1117-
hcfmusp.relation.referenceCampos-Rodriguez F, 2012, ANN INTERN MED, V156, P115, DOI 10.7326/0003-4819-156-2-201201170-00006-
hcfmusp.relation.referenceCano-Pumarega I, 2011, AM J RESP CRIT CARE, V184, P1299, DOI 10.1164/rccm.201101-0130OC-
hcfmusp.relation.referenceCraig SE, 2012, THORAX, V67, P1090, DOI 10.1136/thoraxjnl-2012-202178-
hcfmusp.relation.referenceCui R, 2008, HYPERTENS RES, V31, P501, DOI 10.1291/hypres.31.501-
hcfmusp.relation.referenceDuran J, 2001, AM J RESP CRIT CARE, V163, P685-
hcfmusp.relation.referenceEngleman HM, 1997, THORAX, V52, P114-
hcfmusp.relation.referenceEngleman HM, 1999, AM J RESP CRIT CARE, V159, P461-
hcfmusp.relation.referenceFranklin KA, 2013, EUR RESPIR J, V41, P610, DOI 10.1183/09031936.00212711-
hcfmusp.relation.referenceGauthier L, 2009, SLEEP MED, V10, P329, DOI 10.1016/j.sleep.2008.03.011-
hcfmusp.relation.referenceGiannasi LC, 2013, INT J PROSTHODONT, V26, P334, DOI 10.11607/ijp.3284-
hcfmusp.relation.referenceGottlieb DJ, 2010, CIRCULATION, V122, P352, DOI 10.1161/CIRCULATIONAHA.109.901801-
hcfmusp.relation.referenceGottlieb DJ, 2000, AM J RESP CRIT CARE, V162, P1512-
hcfmusp.relation.referenceGrote L, 1999, AM J RESP CRIT CARE, V160, P1875-
hcfmusp.relation.referenceHaas DC, 2005, CIRCULATION, V111, P614, DOI 10.1161/01.CIR.0000154540.62381.CF-
hcfmusp.relation.referenceHeinzer R, 2015, LANCET RESP MED, V3, P310, DOI 10.1016/S2213-2600(15)00043-0-
hcfmusp.relation.referenceHla KM, 2008, SLEEP, V31, P795-
hcfmusp.relation.referenceHla KM, 2015, SLEEP, V38, P677, DOI 10.5665/sleep.4654-
hcfmusp.relation.referenceHoward ME, 2004, AM J RESP CRIT CARE, V170, P1014, DOI 10.1164/rccm.200312-1782oc-
hcfmusp.relation.referenceHudgel DW, 2012, J CLIN SLEEP MED, V8, P9, DOI 10.5664/jcsm.1648-
hcfmusp.relation.referenceIber C, 2007, AASM MANUAL SCORING-
hcfmusp.relation.referenceIbrahim Abdulsalam Saif, 2007, Ann Saudi Med, V27, P421-
hcfmusp.relation.referenceIp MSM, 2001, CHEST, V119, P62, DOI 10.1378/chest.119.1.62-
hcfmusp.relation.referenceIshman SL, 2010, LARYNGOSCOPE, V120, P2331, DOI 10.1002/lary.21111-
hcfmusp.relation.referenceIsidoro SI, 2013, HEALTH QUAL LIFE OUT, V11, DOI 10.1186/1477-7525-11-207-
hcfmusp.relation.referenceJaimchariyatam N, 2010, SLEEP MED, V11, P837, DOI 10.1016/j.sleep.2010.05.005-
hcfmusp.relation.referenceKapur VK, 2008, SLEEP, V31, P1127-
hcfmusp.relation.referenceKasai T, 2011, AM J HYPERTENS, V24, P401, DOI 10.1038/ajh.2010.248-
hcfmusp.relation.referenceKendzerska T, 2014, PLOS MED, V11, DOI 10.1371/journal.pmed.1001599-
hcfmusp.relation.referenceKezirian EJ, 2009, SLEEP, V32, P253-
hcfmusp.relation.referenceKezirian EJ, 2007, SLEEP, V30, P1181-
hcfmusp.relation.referenceKim J, 2004, AM J RESP CRIT CARE, V170, P1108, DOI 10.1164/rccm.200404-519OC-
hcfmusp.relation.referenceKinoshita LM, 2012, SLEEP BREATH, V16, P1201, DOI 10.1007/s11325-011-0632-8-
hcfmusp.relation.referenceKorostovtseva LS, 2011, MED SCI MONITOR, V17, pCR146-
hcfmusp.relation.referenceKuniyoshi FHS, 2011, CHEST, V140, P62, DOI 10.1378/chest.10-1722-
hcfmusp.relation.referenceKushida CA, 2012, SLEEP, V35, P1593, DOI 10.5665/sleep.2226-
hcfmusp.relation.referenceLavie P, 2000, BRIT MED J, V320, P479, DOI 10.1136/bmj.320.7233.479-
hcfmusp.relation.referenceLecube A, 2010, OBES SURG, V20, P454, DOI 10.1007/s11695-009-0033-2-
hcfmusp.relation.referenceLee JE, 2013, J CLIN SLEEP MED, V9, P997, DOI 10.5664/jcsm.3068-
hcfmusp.relation.referenceLettieri CJ, 2011, J CLIN SLEEP MED, V7, P439, DOI 10.5664/JCSM.1300-
hcfmusp.relation.referenceLittner MR, 2007, CON J CLIN SLEEP MED, V3, P263-
hcfmusp.relation.referenceLopes C, 2008, BRAZ J MED BIOL RES, V41, P908, DOI 10.1590/S0100-879X2008005000036-
hcfmusp.relation.referenceMarin JM, 2005, LANCET, V365, P1046, DOI 10.1016/S0140-6736(05)71141-7-
hcfmusp.relation.referenceMarin JM, 2012, JAMA-J AM MED ASSOC, V307, P2169, DOI 10.1001/jama.2012.3418-
hcfmusp.relation.referenceMarshall NS, 2014, J CLIN SLEEP MED, V10, P355, DOI 10.5664/jcsm.3600-
hcfmusp.relation.referenceMarshall NS, 2008, SLEEP, V31, P1079-
hcfmusp.relation.referenceMartinez-Garcia MA, 2012, EUR RESPIR J, V39, P906, DOI 10.1183/09031936.00011311-
hcfmusp.relation.referenceMason RH, 2011, AM J RESP CRIT CARE, V183, P668, DOI 10.1164/rccm.201001-0051OC-
hcfmusp.relation.referenceMehra R, 2009, ARCH INTERN MED, V169, P1147, DOI 10.1001/archinternmed.2009.138-
hcfmusp.relation.referenceMinoguchi K, 2005, AM J RESP CRIT CARE, V172, P625, DOI 10.1164/rccm.200412-1652OC-
hcfmusp.relation.referenceMinoguchi K, 2007, AM J RESP CRIT CARE, V175, P612, DOI 10.1164/rccm.200608-1141OC-
hcfmusp.relation.referenceMontesi SB, 2012, J CLIN SLEEP MED, V8, P587, DOI 10.5664/jcsm.2170-
hcfmusp.relation.referenceMontserrat J M, 2001, Sleep Breath, V5, P193, DOI 10.1007/s11325-001-0193-3-
hcfmusp.relation.referenceMOSER NJ, 1994, CHEST, V105, P426, DOI 10.1378/chest.105.2.426-
hcfmusp.relation.referenceMulgrew AT, 2008, THORAX, V63, P536, DOI 10.1136/thx.2007.085464-
hcfmusp.relation.referenceNazzaro P, 2008, EUR J CLIN INVEST, V38, P766, DOI 10.1111/j.1365-2362.2008.02011.x-
hcfmusp.relation.referenceNieto FJ, 2000, JAMA-J AM MED ASSOC, V283, P1829, DOI 10.1001/jama.283.14.1829-
hcfmusp.relation.referenceNorman RG, 1997, SLEEP, V20, P1175-
hcfmusp.relation.referenceO'Connor GT, 2009, AM J RESP CRIT CARE, V179, P1159, DOI 10.1164/rccm.200712-1809OC-
hcfmusp.relation.referencePeppard PE, 2006, ARCH INTERN MED, V166, P1709, DOI 10.1001/archinte.166.16.1709-
hcfmusp.relation.referencePeppard PE, 2013, AM J EPIDEMIOL, V177, P1006, DOI 10.1093/aje/kws342-
hcfmusp.relation.referencePeppard PE, 2000, NEW ENGL J MED, V342, P1378, DOI 10.1056/NEJM200005113421901-
hcfmusp.relation.referencePunjabi NM, 2009, PLOS MED, V6, DOI 10.1371/journal.pmed.1000132-
hcfmusp.relation.referencePunjabi NM, 2002, SLEEP, V25, P307-
hcfmusp.relation.referenceQuan SF, 2014, SW J PULM CRIT CARE, V9, P44-
hcfmusp.relation.referenceQuan SF, 2011, SLEEP, V34, P303-
hcfmusp.relation.referenceRedline S, 2000, AM J RESP CRIT CARE, V161, P369-
hcfmusp.relation.referenceRedline S, 1997, SLEEP, V20, P1209-
hcfmusp.relation.referenceRedline S, 2010, AM J RESP CRIT CARE, V182, P269, DOI 10.1164/rccm.200911-1746OC-
hcfmusp.relation.referenceRola R, 2007, J PHYSIOL PHARMACOL, V58, P575-
hcfmusp.relation.referenceRonksley PE, 2009, THORAX, V64, P834, DOI 10.1136/thx.2009.115105-
hcfmusp.relation.referenceRuehland WR, 2009, SLEEP, V32, P150-
hcfmusp.relation.referenceSampliner RE, 2001, GASTROINTEST ENDOSC, V53, P554, DOI 10.1067/mge.2001.114418-
hcfmusp.relation.referenceSamson Pamela, 2012, Prev Chronic Dis, V9, pE46-
hcfmusp.relation.referenceSchlosser RW, 2007, J COMMUN DISORD, V40, P225, DOI 10.1016/j.jcomdis.2006.06.008-
hcfmusp.relation.referenceSerafini FM, 2001, OBES SURG, V11, P28, DOI 10.1381/096089201321454079-
hcfmusp.relation.referenceSeries F, 1999, THORAX, V54, P506-
hcfmusp.relation.referenceShah NA, 2010, SLEEP BREATH, V14, P131, DOI 10.1007/s11325-009-0298-7-
hcfmusp.relation.referenceShahar E, 2001, AM J RESP CRIT CARE, V163, P19-
hcfmusp.relation.referenceSharkey KM, 2013, SLEEP BREATH, V17, P267, DOI 10.1007/s11325-012-0685-3-
hcfmusp.relation.referenceShiomi T, 2002, PSYCHIAT CLIN NEUROS, V56, P333, DOI 10.1046/j.1440-1819.2002.01004.x-
hcfmusp.relation.referenceAbraha I, 1999, SLEEP, V340, pc2697-
hcfmusp.relation.referenceSvensson M, 2008, CHEST, V134, P919, DOI 10.1378/chest.08-0847-
hcfmusp.relation.referenceTheorell-Haglow J, 2008, EUR RESPIR J, V31, P1054, DOI 10.1183/09031936.00074907-
hcfmusp.relation.referenceTregear S, 2009, J CLIN SLEEP MED, V5, P573-
hcfmusp.relation.referenceTufik S, 2010, SLEEP MED, V11, P441, DOI 10.1016/j.sleep.2009.10.005-
hcfmusp.relation.referenceTuomilehto H, 2010, AM J CLIN NUTR, V92, P688, DOI 10.3945/ajcn.2010.29485-
hcfmusp.relation.referenceTuomilehto H, 2014, SLEEP MED, V15, P329, DOI 10.1016/j.sleep.2013.11.786-
hcfmusp.relation.referenceTuomilehto HPI, 2009, AM J RESP CRIT CARE, V179, P320, DOI 10.1164/rccm.200805-669OC-
hcfmusp.relation.referenceTurnbull CD, 2014, THORAX, V69, P950, DOI 10.1136/thoraxjnl-2013-204826-
hcfmusp.relation.referenceUdwadia ZF, 2004, AM J RESP CRIT CARE, V169, P168, DOI 10.1164/rccm.200302-265OC-
hcfmusp.relation.referenceUtriainen KT, 2013, EUR RESPIR J, V41, P616, DOI 10.1183/09031936.00227611-
hcfmusp.relation.referenceValham F, 2008, CIRCULATION, V118, P955, DOI 10.1161/CIRCULATIONAHA.108.783290-
hcfmusp.relation.referenceWachter R, 2013, EUR RESPIR J, V41, P376, DOI 10.1183/09031936.00218211-
hcfmusp.relation.referenceWang H, 2012, SLEEP BIOL RHYTHMS, V10-
hcfmusp.relation.referenceWard KL, 2013, J CLIN SLEEP MED, V9, P1013, DOI 10.5664/jcsm.3072-
hcfmusp.relation.referenceWeaver TE, 2012, AM J RESP CRIT CARE, V186, P677, DOI 10.1164/rccm.201202-0200OC-
hcfmusp.relation.referenceXiromeritis AG, 2011, SLEEP BREATH, V15, P121, DOI 10.1007/s11325-010-0335-6-
hcfmusp.relation.referenceYaggi HK, 2005, NEW ENGL J MED, V353, P2034, DOI 10.1056/NEJMoa043104-
hcfmusp.relation.referenceYaremchuk K, 2011, LARYNGOSCOPE, V121, P1590, DOI 10.1002/lary.21823-
hcfmusp.relation.referenceYeh PS, 2010, OBES SURG, V20, P30, DOI 10.1007/s11695-009-9854-2-
hcfmusp.relation.referenceYoung T, 1997, SLEEP, V20, P705-
hcfmusp.relation.referenceYOUNG T, 1993, NEW ENGL J MED, V328, P1230, DOI 10.1056/NEJM199304293281704-
hcfmusp.relation.referenceYoung T, 1997, ARCH INTERN MED, V157, P1746, DOI 10.1001/archinte.157.15.1746-
hcfmusp.relation.referenceYoung T, 1997, SLEEP, V20, P608-
hcfmusp.relation.referenceYoung T, 2002, AM J RESP CRIT CARE, V165, P1217, DOI 10.1164/rccm.2109080-
hcfmusp.relation.referenceYoung T, 2008, SLEEP, V31, P1071-
dc.description.indexMEDLINE-
dc.identifier.eissn1535-4970-
hcfmusp.citation.scopus88-
hcfmusp.scopus.lastupdate2022-07-08-
Appears in Collections:

Artigos e Materiais de Revistas Científicas - FM/MCM
Departamento de Clínica Médica - FM/MCM

Artigos e Materiais de Revistas Científicas - HC/InCor
Instituto do Coração - HC/InCor

Artigos e Materiais de Revistas Científicas - LIM/09
LIM/09 - Laboratório de Pneumologia

Artigos e Materiais de Revistas Científicas - ODS/03
ODS/03 - Saúde e bem-estar


Files in This Item:
File Description SizeFormat 
art_CHOWDHURI_An_Official_American_Thoracic_Society_Research_Statement_Impact_2016.PDF
  Restricted Access
publishedVersion (English)629.25 kBAdobe PDFView/Open Request a copy

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.