Why we should avoid using inferior turbinate tissue as control to Nasal Polyposis studies

Abstract

Conclusion: The authors are aware that inferior turbinate mucosa presents different properties from middle turbinate mucosa and any data generated using inferior turbinate as control in Nasal Polyposis (NP) should be analysed very carefully. Objective: This study aims to compare the mechanical properties of inferior turbinate mucosa vs middle turbinate mucosa. Materials and methods: The interstitial hydrostatic pressure behaviour was compared during a saline solution infusion between healthy nasal mucosa from inferior turbinate with middle turbinate (four patients). Results: A significant difference, p=0.02, was found in the response of interstitial hydrostatic pressure during the saline injection when the inferior turbinate vs middle turbinate was compared.