Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/1920
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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorCRIADO, Paulo Ricardo-
dc.contributor.authorANTINORI, Lidi Che Leon-
dc.contributor.authorMARUTA, Celina Wakisaka-
dc.contributor.authorREIS, Vitor Manoel Silva dos-
dc.date.accessioned2013-09-23T16:38:12Z-
dc.date.available2013-09-23T16:38:12Z-
dc.date.issued2013-
dc.identifier.citationANAIS BRASILEIROS DE DERMATOLOGIA, v.88, n.3, p.355-360, 2013-
dc.identifier.issn0365-0596-
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/1920-
dc.description.abstractBACKGROUND: It has been demonstrated that neutrophils, eosinophils and monocytes, under appropriated stimulus, may express tissue factor and therefore, activate the extrinsic pathway of coagulation. We performed a transversal and case-control study of patients with chronic urticaria and patients with psoriasis, in our outpatient clinic to evaluate the production of D-dimer. OBJECTIVE: To evaluate D-dimer serum levels in patients with chronic urticaria and its possible correlation with disease activity. PATIENTS AND METHODS: The study was conducted from October 2010 until March 2011. We selected 37 consecutive patients from our Allergy Unit and Psoriasis Unit, and divided them into three groups for statistical analysis: (i) 12 patients with active chronic urticaria (CU); (ii) 10 patients with chronic urticaria under remission and (iii) 15 patients with psoriasis (a disease with skin inflammatory infiltrate constituted by neutrophils, lymphocytes and monocytes). Another five patients with urticarial vasculitis were allocated in our study, but not included in statistical analysis. The serum levels of D-dimer were measured by Enzyme Linked Fluorescent Assay (ELFA), and the result units were given in ng/ml FEU. RESULTS: Patients with active chronic urticaria had the highest serum levels of D-dimer (p<0.01), when compared to patients with CU under remission and the control group (patients with psoriasis). CONCLUSIONS: Patients with active chronic urticaria have higher serum levels of D-dimer, when compared to patients with chronic urticaria under remission and patients with psoriasis. We found elevated serum levels of D-dimer among patients with urticarial vasculitis.-
dc.language.isoeng-
dc.publisherSOC BRASILEIRA DERMATOLOGIA-
dc.relation.ispartofAnais Brasileiros de Dermatologia-
dc.rightsopenAccess-
dc.subjectAngioedema-
dc.subjectPsoriasis-
dc.subjectUrticaria-
dc.subjectVasculitis-
dc.subjectVasculitis, leukocytoclastic, cutaneous-
dc.subject.othertissue factor activity-
dc.subject.otherblood-coagulation-
dc.subject.otherautoantibodies-
dc.subject.otherinflammation-
dc.subject.otheractivation-
dc.subject.otherpathway-
dc.subject.otherplasma-
dc.subject.otherlink-
dc.titleEvaluation of D-dimer serum levels among patients with chronic urticaria, psoriasis and urticarial vasculitis-
dc.typearticle-
dc.rights.holderCopyright SOC BRASILEIRA DERMATOLOGIA-
dc.identifier.doi10.1590/abd1806-4841.20131532-
dc.identifier.pmid23793207-
dc.subject.wosDermatology-
dc.type.categoryoriginal article-
dc.type.versionpublishedVersion-
hcfmusp.author.externalANTINORI, Lidi Che Leon:HC FMUSP, Div Dermatol, Sao Paulo, Brazil-
hcfmusp.description.beginpage355-
hcfmusp.description.endpage360-
hcfmusp.description.issue3-
hcfmusp.description.volume88-
hcfmusp.origemWOS-
hcfmusp.origem.idWOS:000320937800003-
hcfmusp.origem.id2-s2.0-84879596876-
hcfmusp.origem.idSCIELO:S0365-05962013000300355-
hcfmusp.publisher.cityRIO DE JANEIRO RJ-
hcfmusp.publisher.countryBRAZIL-
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dc.description.indexMEDLINE-
hcfmusp.citation.scopus28-
hcfmusp.scopus.lastupdate2022-05-06-
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Artigos e Materiais de Revistas Científicas - FM/MDT
Departamento de Dermatologia - FM/MDT

Artigos e Materiais de Revistas Científicas - HC/ICHC
Instituto Central - HC/ICHC

Artigos e Materiais de Revistas Científicas - LIM/53
LIM/53 - Laboratório de Micologia

Artigos e Materiais de Revistas Científicas - LIM/56
LIM/56 - Laboratório de Investigação em Dermatologia e Imunodeficiências


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