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Title: Bone Loss in Chronic Hemiplegia: A Longitudinal Cohort Study
Authors: BRITO, Christina May Moran deGARCIA, Ana Cristina FerreiraTAKAYAMA, LiliamFREGNI, FelipeBATTISTELLA, Linamara RizzoPEREIRA, Rosa Maria Rodrigues
Citation: JOURNAL OF CLINICAL DENSITOMETRY, v.16, n.2, p.160-167, 2013
Abstract: The purpose of this study was to evaluate hemiplegic stroke patients in terms of long-term changes in bone mineral density and related factors. We conducted a longitudinal cohort study, involving 57 first-stroke patients (40 males) with chronic hemiplegia (for more than 12 mo), at a university rehabilitation center in the city of Sao Paulo, Brazil. Bone loss, body composition, lean mass, and fat mass were evaluated at 2 time points (mean interval, 16 mo). Bone loss was significantly greater in paretic forearms than in nonparetic forearms (p = 0.001) and in patients having suffered strokes more recently (p = 0.015). We found no difference between paretic and nonparetic femurs. Femoral bone loss was significantly greater in patients using anticoagulants or anticonvulsants (p = 0.025) and in those with greater spasticity (p = 0.040), regardless of the time since stroke. Our results provide additional evidence that hemiplegic stroke patients have progressive bone loss and that such bone loss is more common in the arms than in the legs. Patients with poststroke hemiplegia should be densitometric monitored mainly in paretic arm and treated for bone loss, with attention to the determinants identified in this study.
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Artigos e Materiais de Revistas Científicas - FM/MCM
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Artigos e Materiais de Revistas Científicas - LIM/17
LIM/17 - Laboratório de Investigação em Reumatologia

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LIM/40 - Laboratório de Imunohematologia e Hematologia Forense

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