Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/2086
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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorGOMES, Roberta C.-
dc.contributor.authorMARQUES, Victor L. S.-
dc.contributor.authorCAVALCANTE, Erica G. N.-
dc.contributor.authorCAMPOS, Lucia M. A.-
dc.contributor.authorSALLUM, Adriana M.-
dc.contributor.authorTANNURI, Uenis-
dc.contributor.authorSILVA, Clovis A. da-
dc.date.accessioned2013-09-23T16:43:08Z-
dc.date.available2013-09-23T16:43:08Z-
dc.date.issued2013-
dc.identifier.citationJOURNAL OF PEDIATRIC SURGERY, v.48, n.2, p.425-428, 2013-
dc.identifier.issn0022-3468-
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/2086-
dc.description.abstractSystemic childhood polyarteritis nodosa (C-PAN) is a rare primary vasculitis involving medium or small sized arteries. Abdominal angina is an important and serious complication of PAN, occurring usually 15 to 30 min after food intake, and particularly in adult patients. However, to our knowledge, this involvement as the first manifestation of C-PAN was not described. Therefore, we reported herein two C-PAN cases that fulfilled the new criteria for this vasculitis. These patients were young boys that had malignant arterial hypertension and recurrent post-prandial cramping with acute abdomen. Both of them were submitted to laparotomy that revealed multiple and diffuse intestinal necrosis. One of our cases had a severe post-prandial cramping, even after drinking water, and the laparotomy evidenced multiple intestinal perforations. In spite of use of antihypertensive therapies, immunosuppressive agents (corticosteroids, cyclophosphamide and/or methotrexate) and intravenous immunoglobulin, they died possibly due to severe and disseminated activity disease. In conclusion, we described herein the first two fatal cases of C-PAN that presented severe abdominal pain as initial manifestation. We suggest that the diagnosis of PAN should be considered in patients under acute abdominal angina with no apparent etiology.-
dc.description.sponsorshipFAPESP [2008/58238-4]-
dc.description.sponsorshipCNPQ [302724/2011-7]-
dc.description.sponsorshipFederico Foundation-
dc.description.sponsorshipNucleo de Apoio a Pesquisa ""Saude da Crianca e do Adolescente"" da USP (NAP-CriAd)-
dc.language.isoeng-
dc.publisherW B SAUNDERS CO-ELSEVIER INC-
dc.relation.ispartofJournal of Pediatric Surgery-
dc.rightsrestrictedAccess-
dc.subjectChildhood-
dc.subjectPolyarteritis nodosa-
dc.subjectVasculitis-
dc.subjectArterial hypertension-
dc.subjectAbdominal angina-
dc.subject.othergastrointestinal involvement-
dc.subject.otherischemia-
dc.titleSevere intestinal involvement as initial manifestation of systemic childhood polyarteritis nodosa: Report of two cases-
dc.typearticle-
dc.rights.holderCopyright W B SAUNDERS CO-ELSEVIER INC-
dc.identifier.doi10.1016/j.jpedsurg.2012.10.057-
dc.identifier.pmid23414878-
dc.subject.wosPediatrics-
dc.subject.wosSurgery-
dc.type.categoryoriginal article-
dc.type.versionpublishedVersion-
hcfmusp.author.externalMARQUES, Victor L. S.:Univ Sao Paulo, Fac Med, Dept Pediat, Pediat Rheumatol Unit, Sao Paulo, Brazil-
hcfmusp.description.beginpage425-
hcfmusp.description.endpage428-
hcfmusp.description.issue2-
hcfmusp.description.volume48-
hcfmusp.origemWOS-
hcfmusp.origem.idWOS:000314882800039-
hcfmusp.origem.id2-s2.0-84873632919-
hcfmusp.publisher.cityPHILADELPHIA-
hcfmusp.publisher.countryUSA-
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dc.description.indexMEDLINE-
hcfmusp.remissive.sponsorshipCNPq-
hcfmusp.remissive.sponsorshipFAPESP-
hcfmusp.remissive.sponsorshipFederico Foundation-
hcfmusp.remissive.sponsorshipUSP-
hcfmusp.remissive.sponsorshipCNPq-
hcfmusp.remissive.sponsorshipFAPESP-
hcfmusp.remissive.sponsorshipFederico Foundation-
hcfmusp.remissive.sponsorshipUSP-
hcfmusp.citation.scopus7-
hcfmusp.scopus.lastupdate2022-06-17-
Appears in Collections:

Artigos e Materiais de Revistas Científicas - FM/MPE
Departamento de Pediatria - FM/MPE

Artigos e Materiais de Revistas Científicas - HC/ICHC
Instituto Central - HC/ICHC

Artigos e Materiais de Revistas Científicas - HC/ICr
Instituto da Criança - HC/ICr

Artigos e Materiais de Revistas Científicas - LIM/30
LIM/30 - Laboratório de Investigação em Cirurgia Pediátrica

Artigos e Materiais de Revistas Científicas - LIM/36
LIM/36 - Laboratório de Pediatria Clínica

Artigos e Materiais de Revistas Científicas - ODS/03
ODS/03 - Saúde e bem-estar


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