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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorSARTORI, Ana Marli Christovam-
dc.contributor.authorROZMAN, Luciana Martins-
dc.contributor.authorDECIMONI, Tassia Cristina-
dc.contributor.authorLEANDRO, Roseli-
dc.contributor.authorNOVAES, Hillegonda Maria Dutilh-
dc.contributor.authorSOAREZ, Patricia Coelho de-
dc.identifier.citationHUMAN VACCINES & IMMUNOTHERAPEUTICS, v.13, n.6, p.1454-1465, 2017-
dc.description.abstractBackground: In Brazil, since 2005, the Ministry of Health requires Health Economic Evaluation (HEE) of vaccines for introduction into the National Immunization Program.Objectives: To describe and analyze the full HEE on vaccines conducted in Brazil from 1980 to 2013.Methods: Systematic review of the literature. We searched multiple databases. Two researchers independently selected the studies and extracted the data. The methodological quality of individual studies was evaluated using CHEERS items.Results: Twenty studies were reviewed. The most evaluated vaccines were pneumococcal (25%) and HPV (15%). The most used types of HEE were cost-effectiveness analysis (45%) and cost-utility analysis (20%). The research question and compared strategies were stated in all 20 studies and the target population was clear in 95%. Nevertheless, many studies did not inform the perspective of analysis or data sources.Conclusions: HEE of vaccines in Brazil has increased since 2008. However, the studies still have methodological deficiencies.-
dc.description.sponsorshipFundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP, Sao Paulo Research Foundation), as part of a larger project entitled ""Systematic review of health economic evaluations conducted in Brazil (FAPESP) [2012/22126-3]-
dc.description.sponsorshipConselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq, National Counsel of Technological and Scientific Development) - CNPq ) [305614/2013-4]-
dc.description.sponsorshipNational Institute of Science and Technology for Health Technology Assessment (IATS) - CNPq/Brazil-
dc.publisherTAYLOR & FRANCIS INC-
dc.relation.ispartofHuman Vaccines & Immunotherapeutics-
dc.subjectcost-benefit analysis-
dc.subjectcost effectiveness-
dc.subjecteconomic evaluation-
dc.subjectimmunization programs-
dc.subjectsystematic review-
dc.subject.othercost-effectiveness analysis-
dc.subject.otherpneumococcal conjugate vaccine-
dc.subject.othereffectiveness thresholds-
dc.subject.otherimmunization program-
dc.titleA systematic review of health economic evaluations of vaccines in Brazil-
dc.rights.holderCopyright TAYLOR & FRANCIS INC-
dc.subject.wosBiotechnology & Applied Microbiology-
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Artigos e Materiais de Revistas Científicas - FM/MIP
Departamento de Moléstias Infecciosas e Parasitárias - FM/MIP

Artigos e Materiais de Revistas Científicas - FM/MPR
Departamento de Medicina Preventiva - FM/MPR

Artigos e Materiais de Revistas Científicas - HC/ICHC
Instituto Central - HC/ICHC

Artigos e Materiais de Revistas Científicas - LIM/38
LIM/38 - Laboratório de Epidemiologia e Imunobiologia

Artigos e Materiais de Revistas Científicas - LIM/39
LIM/39 - Laboratório de Processamento de Dados Biomédicos

Artigos e Materiais de Revistas Científicas - LIM/48
LIM/48 - Laboratório de Imunologia

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