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https://observatorio.fm.usp.br/handle/OPI/214
Title: | A comparison of non-HDL and LDL cholesterol goal attainment in a large, multinational patient population: The Lipid Treatment Assessment Project 2 |
Authors: | SANTOS, Raul D.; WATERS, David D.; TARASENKO, Lisa; MESSIG, Michael; JUKEMA, J. Wouter; CHIANG, Cheng-Wen; FERRIERES, Jean; FOODY, JoAnne M. |
Citation: | ATHEROSCLEROSIS, v.224, n.1, p.150-153, 2012 |
Abstract: | Objective: This study evaluated the success in attaining non-HDL-cholesterol (non-HDL-C) goals in the multinational L-TAP 2 study. Methods: 9955 patients >= 20 years of age with dyslipidemia on stable lipid-lowering therapy were enrolled from nine countries. Results: Success rates for non-HDL-C goals were 86% in low, 70% in moderate, and 52% in high-risk patients (63% overall). In patients with triglycerides of >200 mg/dL success rates for non-HDL-C goals were 35% vs. 69% in those with <= 200 mg/dL (p < 0.0001). Among patients attaining their LDL-C goal, 18% did not attain their non-HDL-C goal. In those with coronary disease and at least two risk factors, only 34% and 30% attained respectively their non-HDL-C and LDL-C goals. Rates of failure in attaining both LDL-C and non-HDL-C goals were highest in Latin America. Conclusions: Non-HDL-C goal attainment lagged behind LDL-C goal attainment; this gap was greatest in higher-risk patients. |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/MCP Artigos e Materiais de Revistas Científicas - HC/InCor |
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art_SANTOS_A_comparison_of_non_HDL_and_LDL_cholesterol_2012_eng.pdf Restricted Access | publishedVersion (English) | 121.65 kB | Adobe PDF | View/Open Request a copy |
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