Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/2225
Title: Primary neural leprosy: systematic review
Authors: GARBINO, Jose AntonioMARQUES JR., WilsonBARRETO, Jaison AntonioHEISE, Carlos OttoRODRIGUES, Marcia Maria JardimANTUNES, Sergio L.SOARES, Cleverson TeixeiraFLORIANO, Marcos CesarNERY, Jose AugustoTRINDADE, Maria Angelo BianconciniCARVALHO, Noemia BarbosaANDRADA, Nathalia Carvalho deBARREIRA, Amilton AntunesVIRMOND, Marcos da Cunha Lopes
Citation: ARQUIVOS DE NEURO-PSIQUIATRIA, v.71, n.6, p.397-404, 2013
Abstract: The authors proposed a systematic review on the current concepts of primary neural leprosy by consulting the following online databases: MEDLINE, Lilacs/SciELO, and Embase. Selected studies were classified based on the degree of recommendation and levels of scientific evidence according to the ""Oxford Centre for Evidence-based Medicine"". The following aspects were reviewed: cutaneous clinical and laboratorial investigations, i.e. skin clinical exam, smears, and biopsy, and Mitsuda's reaction; neurological investigation (anamnesis, electromyography and nerve biopsy); serological investigation and molecular testing, i.e. serological testing for the detection of the phenolic glycolipid 1 (PGL-1) and the polymerase chain reaction (PCR); and treatment (classification criteria for the definition of specific treatment, steroid treatment, and cure criteria).
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