Conjoined twins pregnancies: experience with 36 cases from a single center

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dc.contributor Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.author BRIZOT, M. L. FMUSP-HC
LIAO, A. W. FMUSP-HC
LOPES, L. M. FMUSP-HC
OKUMURA, M. FMUSP-HC
MARQUES, M. S.
KREBS, V. FMUSP-HC
SCHULTZ, R. FMUSP-HC
ZUGAIB, M. FMUSP-HC
dc.date.issued 2011
dc.identifier.citation PRENATAL DIAGNOSIS, v.31, n.12, p.1120-1125, 2011
dc.identifier.issn 0197-3851
dc.identifier.uri http://observatorio.fm.usp.br/handle/OPI/23188
dc.description.abstract Objective To review a single center's experience in the management of twin pregnancies with conjoined fetuses. Methods Retrospective study describing prenatal findings, delivery details, surgical treatment and perinatal outcome. Results The study included 36 twin pregnancies with conjoined twins seen over a period of 12 years in a single tertiary hospital: 69.4% were thoracopagus, 13.9% parapagus, 8.3% omphaloischiopagus 5.6% omphalopagus and 2.8% cephalopagus. Cardiac defects were present in 91.6% of twin pairs and associated malformations were present in 61.8% of the cases: limb abnormalities in 36.1%, abdominal wall defects in 25.0%, cleft lip and/ or palate in 13.9% and congenital diaphragmatic hernia in 5.5%. Surgical separation was considered not feasible and prognosis lethal in 30 (83.3%) cases. Termination of pregnancy was performed in 12 pregnancies of poor prognosis. Cesarean section was performed in all remaining cases. Five sets of twins underwent surgical separation and six children survived. Overall survival in our series was 8.3% and, among the livebirths, 13.6%. Conclusion Conjoined twin pregnancies should be referred to tertiary centers for detailed fetal anomaly and echocardiographic assessment to evaluate prognosis and determine the possibility of postnatal surgical separation.
dc.language.iso eng
dc.publisher WILEY-BLACKWELL
dc.relation.ispartof Prenatal Diagnosis
dc.rights restrictedAccess
dc.subject twin pregnancy; conjoined twins; ultrasonography; fetal ecocardiography; prenatal diagnosis
dc.subject.other diagnosis
dc.title Conjoined twins pregnancies: experience with 36 cases from a single center
dc.type article
dc.rights.holder Copyright WILEY-BLACKWELL
dc.description.group LIM/14
dc.description.group LIM/36
dc.description.group LIM/57
dc.identifier.doi 10.1002/pd.2843
dc.identifier.pmid 21905053
dc.type.category original article
dc.type.version publishedVersion
hcfmusp.author BRIZOT, M. L.:FM:MOG
hcfmusp.author LIAO, A. W.:FM:MOG
hcfmusp.author LOPES, L. M.:HC:ICHC
hcfmusp.author OKUMURA, M.:HC:ICHC
hcfmusp.author KREBS, V.:HC:ICR
hcfmusp.author SCHULTZ, R.:HC:ICHC
hcfmusp.author ZUGAIB, M.:FM:MOG
hcfmusp.author.external · MARQUES, M. S.:Univ Sao Paulo, Dept Pediat Surg, Hosp Clin, Sch Med, Sao Paulo, Brazil
hcfmusp.origem.id WOS:000298262300002
hcfmusp.origem.id 2-s2.0-82255179478
hcfmusp.publisher.city MALDEN
hcfmusp.publisher.country USA
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dc.description.index MEDLINE
hcfmusp.citation.scopus 25
hcfmusp.affiliation.country Brasil
hcfmusp.scopus.lastupdate 2021-08-27


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