Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/23226
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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorPINHEIRO, W.-
dc.contributor.authorPEREIRA, A. K. Cavalcante-
dc.contributor.authorSOARES JR., J. M.-
dc.contributor.authorBARACAT, E. C.-
dc.date.accessioned2017-11-27T16:32:24Z-
dc.date.available2017-11-27T16:32:24Z-
dc.date.issued2011-
dc.identifier.citationEUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, v.32, n.1, p.37-39, 2011-
dc.identifier.issn0392-2936-
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/23226-
dc.description.abstractObjective: To determine the effectiveness of the combination of mitomycin C, bleomycin and methotrexate as a neoadjuvant treatment in preparation for surgical treatment of cervical cancer. Methods and Materials: Twenty-seven patients with carcinoma of the uterine cervix (stages exophytic IB2 and IIB-IIIB) who had not previously undergone any treatment received mitomycin C, bleomycin and methotrexate in five sessions, once every four weeks. Results: The objective response rate was approximately 81%, including 16 complete responses and six partial responses. Significant toxic effects were not observed. Responsive patients underwent surgery and remained without evidence of disease for the next 20 years. Unresponsive patients did not fare well and passed away within five years after treatment. Conclusion: Our data suggest that this strategy may be effective for advanced cases, enabling patients to receive surgical treatment.-
dc.language.isoeng-
dc.publisherI R O G CANADA, INC-
dc.relation.ispartofEuropean Journal of Gynaecological Oncology-
dc.rightsrestrictedAccess-
dc.subjectBleomycin-
dc.subjectMitomycin-
dc.subjectMethotrexate-
dc.subjectCervical cancer-
dc.subjectChemotherapy-
dc.subject.otheruterine cervix-
dc.subject.othercell carcinoma-
dc.subject.otherchemotherapy-
dc.subject.othertumor-
dc.titleIs the combination of mitomycin C, bleomycin and methotrexate effective as a neoadjuvant treatment for cervical cancer in women?-
dc.typearticle-
dc.rights.holderCopyright I R O G CANADA, INC-
dc.identifier.pmid21446322-
dc.subject.wosOncology-
dc.subject.wosObstetrics & Gynecology-
dc.type.categoryoriginal article-
dc.type.versionpublishedVersion-
hcfmusp.description.beginpage37-
hcfmusp.description.endpage39-
hcfmusp.description.issue1-
hcfmusp.description.volume32-
hcfmusp.origemWOS-
hcfmusp.origem.idWOS:000286914800006-
hcfmusp.publisher.cityMONTREAL-
hcfmusp.publisher.countryCANADA-
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dc.description.indexMEDLINE-
Appears in Collections:

Artigos e Materiais de Revistas Científicas - FM/MOG
Departamento de Obstetrícia e Ginecologia - FM/MOG

Artigos e Materiais de Revistas Científicas - HC/ICESP
Instituto do Câncer do Estado de São Paulo - HC/ICESP

Artigos e Materiais de Revistas Científicas - HC/ICHC
Instituto Central - HC/ICHC

Artigos e Materiais de Revistas Científicas - LIM/58
LIM/58 - Laboratório de Ginecologia Estrutural e Molecular


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