Loss of interest, depressed mood and impact on the quality of life: Cross-sectional survey

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dc.contributor Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.author GUAJARDO, Valeri D. FMUSP-HC
SOUZA, Bruno P. F. FMUSP-HC
HENRIQUES, Sergio G.
LUCIA, Mara C. S. FMUSP-HC
MENEZES, Paulo R. FMUSP-HC
MARTINS, Milton A. FMUSP-HC
TARDIVO, Leila S. L. P. C.
GATTAZ, Wagner F. FMUSP-HC
FRAGUAS, Renerio FMUSP-HC
dc.date.issued 2011
dc.identifier.citation BMC PUBLIC HEALTH, v.11, article ID 826, 7p, 2011
dc.identifier.issn 1471-2458
dc.identifier.uri http://observatorio.fm.usp.br/handle/OPI/23371
dc.description.abstract Background: Depressive symptoms and chronic disease have adverse effects on patients' health-related quality of life (H-RQOL). However, little is known about this effect on H-RQOL when only the two core depressive symptoms - loss of interest and depressed mood - are considered. The objective of this study is to investigate H-RQOL in the presence of loss of interest and depressed mood at a general medical outpatient unit. Methods: We evaluated 553 patients at their first attendance at a general medical outpatient unit of a teaching hospital. H-RQOL was assessed with the Medical Outcomes Study 36-item Short-Form Health Survey (SF-36). Depressed mood and loss of interest were assessed by the Primary Care Evaluation of Mental Disorders (PRIME-MD)Patient Questionnaire. A physician performed the diagnosis of chronic diseases by clinical judgment and classified them in 13 possible pre-defined categories. We used multiple linear regression to investigate associations between each domain of H-RQOL and our two core depression symptoms. The presence of chronic diseases and demographic variables were included in the models as covariates. Results: Among the 553 patients, 70.5% were women with a mean age of 41.0 years (range 18-85, SD +/- 15.4). Loss of interest was reported by 54.6%, and depressed mood by 59.7% of the patients. At least one chronic disease was diagnosed in 59.5% of patients; cardiovascular disease was the most prevalent, affecting 20.6% of our patients. Loss of interest and depressed mood was significantly associated with decreased scores in all domains of H-RQOL after adjustment for possible confounders. The presence of any chronic disease was associated with a decrease in the domain of vitality. The analysis of each individual chronic disease category revealed that no category was associated with a decrease in more than one domain of H-RQOL. Conclusion: Loss of interest and depressed mood were associated with significant decreases in H-RQOL. We recommend these simple tests for screening in general practice.
dc.description.sponsorship · State of Sao Paulo Research Foundation (FAPESP), Brazil [00669-9]
dc.language.iso eng
dc.publisher BIOMED CENTRAL LTD
dc.relation.ispartof BMC Public Health
dc.rights openAccess
dc.subject.other primary-care; major depression; general-practice; medical outcomes; mental-disorders; chronic diseases; 2 questions; health; prevalence; association
dc.title Loss of interest, depressed mood and impact on the quality of life: Cross-sectional survey
dc.type article
dc.rights.holder Copyright BIOMED CENTRAL LTD
dc.description.group LIM/20
dc.description.group LIM/21
dc.description.group LIM/27
dc.identifier.doi 10.1186/1471-2458-11-826
dc.identifier.pmid 22026632
dc.type.category original article
dc.type.version publishedVersion
hcfmusp.author GUAJARDO, Valeri D.:HC:ICHC
hcfmusp.author SOUZA, Bruno P. F.:HC:IPQ
hcfmusp.author LUCIA, Mara C. S.:HC:ICHC
hcfmusp.author MENEZES, Paulo R.:FM:MPR
hcfmusp.author MARTINS, Milton A.:FM:MCM
hcfmusp.author GATTAZ, Wagner F.:FM:MPS
hcfmusp.author FRAGUAS, Renerio:FM:MPS
hcfmusp.author.external · HENRIQUES, Sergio G.:Univ Sao Paulo, Fac Med, Clin Hosp, Inst Psychiat,Dept Psychiat, BR-05403010 Sao Paulo, Brazil
· TARDIVO, Leila S. L. P. C.:Univ Sao Paulo, Inst Psychol, Dept Clin Psychol, BR-05508030 Sao Paulo, Brazil
hcfmusp.origem.id 2-s2.0-80054873392
hcfmusp.origem.id WOS:000296797700001
hcfmusp.publisher.city LONDON
hcfmusp.publisher.country ENGLAND
hcfmusp.relation.reference · Fleck MPD, 2002, REV SAUDE PUBL, V36, P431, DOI 10.1590/S0034-89102002000400008
· Angermeyer MC, 1997, PSYCHOL MED, V27, P131, DOI 10.1017/S0033291796004205
· HAYS RD, 1995, ARCH GEN PSYCHIAT, V52, P11
· King M, 2008, BRIT J PSYCHIAT, V192, P362, DOI 10.1192/bjp.bp.107.039966
· BLAZER DG, 1994, AM J PSYCHIAT, V151, P979
· Whooley MA, 1997, J GEN INTERN MED, V12, P439, DOI 10.1046/j.1525-1497.1997.00076.x
· Cuijpers P, 2002, J AFFECT DISORDERS, V72, P227, DOI 10.1016/S0165-0327(01)00413-X
· Ustun TB, 2004, BRIT J PSYCHIAT, V184, P386, DOI 10.1192/bjp.184.5.386
· DEW MA, 1991, SOC PSYCH PSYCH EPID, V26, P230, DOI 10.1007/BF00788971
· van den Akker M, 1998, J CLIN EPIDEMIOL, V51, P367, DOI 10.1016/S0895-4356(97)00306-5
· Angermeyer MC, 2002, INT J SOC PSYCHIATR, V48, P189, DOI 10.1177/002076402128783235
· Wells KB, 1999, ARCH GEN PSYCHIAT, V56, P897, DOI 10.1001/archpsyc.56.10.897
· Egede LE, 2007, GEN HOSP PSYCHIAT, V29, P409, DOI 10.1016/j.genhosppsych.2007.06.002
· Lichtman JH, 2008, CIRCULATION, V118, P1768, DOI 10.1161/CIRCULATIONAHA.108.190769
· WELLS KB, 1989, JAMA-J AM MED ASSOC, V262, P914, DOI 10.1001/jama.262.7.914
· Katon W, 2002, J PSYCHOSOM RES, V53, P859, DOI 10.1016/S0022-3999(02)00313-6
· Mohr DC, 2007, MULT SCLER, V13, P215, DOI 10.1177/1352458506070926
· Muller-Tasch T, 2007, J CARD FAIL, V13, P818, DOI 10.1016/j.cardfail.2007.07.008
· Lam CLK, 2000, FAM PRACT, V17, P159, DOI 10.1093/fampra/17.2.159
· Berardi D, 2002, FAM PRACT, V19, P397, DOI 10.1093/fampra/19.4.397
· Bonicatto SC, 2001, SOC SCI MED, V52, P911, DOI 10.1016/S0277-9536(00)00192-1
· Ciconelli RM, 1997, TRADUCAO PORTUGUES V
· Fortin M, 2007, HEALTH QUAL LIFE OUT, V5, DOI 10.1186/1477-7525-5-52
· Fraguas R, 2006, J AFFECT DISORDERS, V91, P11, DOI 10.1016/j.jad.2005.12.003
· Goldberg D, 1995, FAM PRACT, V12, P466, DOI 10.1093/fampra/12.4.466
· Henriques SG, 2009, CLINICS, V64, P629, DOI 10.1590/S1807-59322009000700004
· Huffman JC, 2006, HEART, V92, P1656, DOI 10.1136/hrt.2005.087213
· Jaracz K, 2002, ACTA NEUROPSYCHIATR, V14, P219, DOI 10.1034/j.1601-5215.2002.140504.x
· LONNQVIST J, 1994, ACTA PSYCHIAT SCAND, V89, P363, DOI 10.1111/j.1600-0447.1994.tb01530.x
· Mitchell AJ, 2009, PSYCHOL MED, V39, P1107, DOI 10.1017/S0033291708004674
· Pyne JM, 1997, PSYCHIATR SERV, V48, P224
· Rabelo Dóris Firmino, 2006, Estud. psicol. (Natal), V11, P169, DOI 10.1590/S1413-294X2006000200006
· *ROYAL COLL PSYCH, 2004, NAT CLIN PRACT GUID, P53
· Schwenk TL, 1996, GEN HOSP PSYCHIAT, V18, P407, DOI 10.1016/S0163-8343(96)00062-X
· STEWART AL, 1989, JAMA-J AM MED ASSOC, V262, P907, DOI 10.1001/jama.262.7.907
· Thommasen Harvey V, 2006, Rural Remote Health, V6, P528
· Wang HM, 2008, BMC PUBLIC HEALTH, V8, DOI 10.1186/1471-2458-8-246
· WARE JE, 1992, MED CARE, V30, P473, DOI 10.1097/00005650-199206000-00002
dc.description.index MEDLINE
hcfmusp.citation.scopus 9
hcfmusp.affiliation.country Brasil
hcfmusp.scopus.lastupdate 2021-08-27


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