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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorSILVEIRA, Camila Magalhaes-
dc.contributor.authorVIANA, Maria Carmen-
dc.contributor.authorSIU, Erica Rosanna-
dc.contributor.authorANDRADE, Arthur Guerra de-
dc.contributor.authorANTHONY, James C.-
dc.contributor.authorANDRADE, Laura Helena-
dc.identifier.citationALCOHOL AND ALCOHOLISM, v.46, n.3, p.324-332, 2011-
dc.description.abstractAims: To evaluate sociodemographic correlates associated with transitions from alcohol use to disorders and remission in a Brazilian population. Methods: Data are from a probabilistic, multi-stage clustered sample of adult household residents in the Sao Paulo Metropolitan Area. Alcohol use, regular use (at least 12 drinks/year), DSM-IV abuse and dependence and remission from alcohol use disorders (AUDs) were assessed with the World Mental Health version of the Composite International Diagnostic Interview. Age of onset (AOO) distributions of the cumulative lifetime probability of each alcohol use stage were prepared with data obtained from 5037 subjects. Correlates of transitions were obtained from a subsample of 2942 respondents, whose time-dependent sociodemographic data were available. Results: Lifetime prevalences were 85.8% for alcohol use, 56.2% for regular use, 10.6% for abuse and 3.6% for dependence; 73.4 and 58.8% of respondents with lifetime abuse and dependence, respectively, had remitted. The number of sociodemographic correlates decreased from alcohol use to disorders. All transitions across alcohol use stages up to abuse were consistently associated with male gender, younger cohorts and lower education. Importantly, low education was a correlate for developing AUD and not remitting from dependence. Early AOO of first alcohol use was associated with the transition of regular use to abuse. Conclusion: The present study demonstrates that specific correlates differently contribute throughout alcohol use trajectory in a Brazilian population. It also reinforces the need of preventive programs focused on early initiation of alcohol use and high-risk individuals, in order to minimize the progression to dependence and improve remission from AUD.-
dc.description.sponsorshipFundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [03/00204-3]-
dc.description.sponsorshipFundo de Apoio a Ciencia e Tecnologia do Municipio de Vitoria (FACITEC-Vitoria Foundation for Science and Technology) [002/2003]-
dc.description.sponsorshipSao Paulo State Secretaria de Seguranca Publica-
dc.description.sponsorshipUnited States National Institute of Mental Health [R01-MH070884]-
dc.description.sponsorshipJohn D. and Catherine T. MacArthur Foundation-
dc.description.sponsorshipPfizer Foundation-
dc.description.sponsorshipUS Public Health Service [R13-MH066849, R01-MH069864, R01-DA016558]-
dc.description.sponsorshipFogarty International Center [FIRCA R03-TW006481]-
dc.description.sponsorshipPan American Health Organization-
dc.description.sponsorshipEli Lilly & Company Foundation-
dc.description.sponsorshipOrtho-McNeil Pharmaceutical, Inc.-
dc.description.sponsorshipBristol-Myers Squibb-
dc.publisherOXFORD UNIV PRESS-
dc.relation.ispartofAlcohol and Alcoholism-
dc.subject.other1st drink-
dc.titleSociodemographic Correlates of Transitions from Alcohol Use to Disorders and Remission in the Sao Paulo Megacity Mental Health Survey, Brazil-
dc.rights.holderCopyright OXFORD UNIV PRESS-
dc.subject.wosSubstance Abuse-
dc.type.categoryoriginal article-
dc.type.versionpublishedVersion-, Erica Rosanna:Univ Sao Paulo, Sch Med, Dept Psychiat, Sect Psychiat Epidemiol LIM 23,CEAPESQ, Sao Paulo, Brazil; Univ Sao Paulo, Sch Med, Inst Psychiat, CEAPESQ, Sao Paulo, Brazil-, James C.:Michigan State Univ, Coll Human Med, Dept Epidemiol, E Lansing, MI 48824 USA-
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Artigos e Materiais de Revistas Científicas - FM/MPS
Departamento de Psiquiatria - FM/MPS

Artigos e Materiais de Revistas Científicas - HC/ICHC
Instituto Central - HC/ICHC

Artigos e Materiais de Revistas Científicas - HC/IPq
Instituto de Psiquiatria - HC/IPq

Artigos e Materiais de Revistas Científicas - LIM/23
LIM/23 - Laboratório de Psicopatologia e Terapêutica Psiquiátrica

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