1. Início
  2. Faculdade de Medicina - FM
  3. Departamento de Psiquiatria - FM/MPS
  4. Artigos e Materiais de Revistas Científicas - FM/MPS
Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/23425
Full metadata record
DC FieldValueLanguage
dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorHU, Li Wen-
dc.contributor.authorKAWAMOTO, Elisa Mitiko-
dc.contributor.authorBRIETZKE, Elisa-
dc.contributor.authorSCAVONE, Cristoforo-
dc.contributor.authorLAFER, Beny-
dc.date.accessioned2017-11-27T16:34:35Z-
dc.date.available2017-11-27T16:34:35Z-
dc.date.issued2011-
dc.identifier.citationPROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, v.35, n.1, p.11-17, 2011-
dc.identifier.issn0278-5846-
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/23425-
dc.description.abstractThe neurobiology of Bipolar Disorder (BD) is not completely understood, although abnormalities in neuroplasticity and control of apoptosis have been considered as central events in its pathophysiology. The molecules of the Wnt family comprise a class of proteins that control essential developmental processes such as embryonic patterning, cell growth, migration, and differentiation with their actions largely exerted by modulating gene transcription. The Wnt signaling pathway has interface with some mediators with a well documented action in neuroplasticity and regulation of cell surviving. In addition, mood stabilizers such as lithium and valproate may have their neuroprotective properties in part mediated by the Wnt pathway. This article is an overview of how the Wnt signaling cascade might be involved in the pathogenesis of BD and also in details of intracellular events related to this pathway. Further studies of Wnt signaling may lead to a better comprehension of the neuroprotective actions of mood stabilizers and contribute to improving the therapeutics of BD.-
dc.description.sponsorshipFundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [2008/06948-8, 2008/08191-1]-
dc.language.isoeng-
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD-
dc.relation.ispartofProgress in Neuro-Psychopharmacology & Biological Psychiatry-
dc.rightsrestrictedAccess-
dc.subjectBipolar disorder-
dc.subjectGSK3 beta-
dc.subjectInflammation-
dc.subjectNeuroplasticity-
dc.subjectWnt-
dc.subject.otherglycogen-synthase kinase-3-
dc.subject.othersubgenual prefrontal cortex-
dc.subject.othermajor depressive disorder-
dc.subject.otherneurotrophic factor-
dc.subject.otherlithium treatment-
dc.subject.otherbeta-catenin-
dc.subject.otheroxidative stress-
dc.subject.otherpsychiatric-disorders-
dc.subject.othertransduction pathways-
dc.subject.othereuthymic patients-
dc.titleThe role of Wnt signaling and its interaction with diverse mechanisms of cellular apoptosis in the pathophysiology of bipolar disorder-
dc.typearticle-
dc.rights.holderCopyright PERGAMON-ELSEVIER SCIENCE LTD-
dc.identifier.doi10.1016/j.pnpbp.2010.08.031-
dc.identifier.pmid20828594-
dc.subject.wosClinical Neurology-
dc.subject.wosNeurosciences-
dc.subject.wosPharmacology & Pharmacy-
dc.subject.wosPsychiatry-
dc.type.categoryreview-
dc.type.versionpublishedVersion-
hcfmusp.author.externalKAWAMOTO, Elisa Mitiko:Univ Sao Paulo, Dept Pharmacol, Inst Biomed Sci, BR-01060970 Sao Paulo, Brazil-
hcfmusp.author.externalSCAVONE, Cristoforo:Univ Sao Paulo, Dept Pharmacol, Inst Biomed Sci, BR-01060970 Sao Paulo, Brazil-
hcfmusp.description.beginpage11-
hcfmusp.description.endpage17-
hcfmusp.description.issue1-
hcfmusp.description.volume35-
hcfmusp.origemWOS-
hcfmusp.origem.id2-s2.0-78650958063-
hcfmusp.origem.idWOS:000287271400002-
hcfmusp.publisher.cityOXFORD-
hcfmusp.publisher.countryENGLAND-
hcfmusp.relation.referenceCiani L, 2005, NAT REV NEUROSCI, V6, P351, DOI 10.1038/nrn1665-
hcfmusp.relation.referenceFilomeni G, 2006, ANTIOXID REDOX SIGN, V8, P2187, DOI 10.1089/ars.2006.8.2187-
hcfmusp.relation.referenceRowe MK, 2007, NEUROSCI BIOBEHAV R, V31, P920, DOI 10.1016/j.neubiorev.2007.03.002-
hcfmusp.relation.referencePrickaerts J, 2006, J NEUROSCI, V26, P9022, DOI 10.1523/JNEUROSCI.5216-05.2006-
hcfmusp.relation.referenceChuang DM, 2005, ANN NY ACAD SCI, V1053, P195, DOI 10.1196/annals.1344.018-
hcfmusp.relation.referenceKim YK, 2007, J AFFECT DISORDERS, V104, P91, DOI 10.1016/j.jad.2007.02.018-
hcfmusp.relation.referenceKato T, 2000, BIPOLAR DISORD, V2, P180, DOI 10.1034/j.1399-5618.2000.020305.x-
hcfmusp.relation.referencePolter A, 2010, NEUROPSYCHOPHARMACOL, V35, P1761, DOI 10.1038/npp.2010.43-
hcfmusp.relation.referenceOngur D, 1998, P NATL ACAD SCI USA, V95, P13290, DOI 10.1073/pnas.95.22.13290-
hcfmusp.relation.referenceBeaulieu JM, 2004, P NATL ACAD SCI USA, V101, P5099, DOI 10.1073/pnas.0307921101-
hcfmusp.relation.referenceLi XH, 2007, INT J NEUROPSYCHOPH, V10, P7, DOI 10.1017/S1461145706006547-
hcfmusp.relation.referenceSen M, 2000, P NATL ACAD SCI USA, V97, P2791, DOI 10.1073/pnas.050574297-
hcfmusp.relation.referenceO'Brien SM, 2006, J AFFECT DISORDERS, V90, P263, DOI 10.1016/j.jad.2005.11.015-
hcfmusp.relation.referenceNovina CD, 2004, NATURE, V430, P161, DOI 10.1038/430161a-
hcfmusp.relation.referenceDavid MD, 2008, J CELL SCI, V121, P2718, DOI 10.1242/jcs.029660-
hcfmusp.relation.referenceMachado-Vieira R, 2007, BIOL PSYCHIAT, V61, P142, DOI 10.1016/j.biopsych.2006.03.070-
hcfmusp.relation.referenceGould TD, 2004, INT J NEUROPSYCHOPH, V7, P387, DOI 10.1017/S1461145704004535-
hcfmusp.relation.referenceZanetti MV, 2009, EUR ARCH PSY CLIN N, V259, P316, DOI 10.1007/s00406-009-0002-8-
hcfmusp.relation.referenceBrietzke E, 2009, BRAIN BEHAV IMMUN, V23, P1079, DOI 10.1016/j.bbi.2009.04.008-
hcfmusp.relation.referenceBlumenthal A, 2006, BLOOD, V108, P965, DOI 10.1182/blood-2005-12-5046-
hcfmusp.relation.referencePost RM, 2007, NEUROSCI BIOBEHAV R, V31, P858, DOI 10.1016/j.neubiorev.2007.04.003-
hcfmusp.relation.referenceVeeman MT, 2003, CURR BIOL, V13, P680, DOI 10.1016/S0960-9822(03)00240-9-
hcfmusp.relation.referenceDU SJ, 1995, MOL CELL BIOL, V15, P2625-
hcfmusp.relation.referenceMcAfoose J, 2009, PSYCHONEUROENDOCRINO, V34, P615, DOI 10.1016/j.psyneuen.2008.10.006-
hcfmusp.relation.referenceSchiepers OJG, 2005, PROG NEURO-PSYCHOPH, V29, P201, DOI 10.1016/j.pnpbp.2004.11.003-
hcfmusp.relation.referenceMonteleone P, 2008, BIPOLAR DISORD, V10, P95, DOI 10.1111/j.1399-5618.2008.00459.x-
hcfmusp.relation.referenceDissanayake SK, 2007, J BIOL CHEM, V282, P17259, DOI 10.1074/jbc.M700075200-
hcfmusp.relation.referenceZandi PP, 2008, ARCH GEN PSYCHIAT, V65, P785, DOI 10.1001/archpsyc.65.7.785-
hcfmusp.relation.referenceGould TD, 2004, NEUROPSYCHOPHARMACOL, V29, P32, DOI 10.1038/sj.npp.1300283-
hcfmusp.relation.referenceKarege F, 2007, BIOL PSYCHIAT, V61, P240, DOI 10.1016/j.biopsych.2006.04.036-
hcfmusp.relation.referenceRaison CL, 2009, BRAIN BEHAV IMMUN, V23, P327, DOI 10.1016/j.bbi.2008.11.005-
hcfmusp.relation.referenceJin TR, 2008, CELL SIGNAL, V20, P1697, DOI 10.1016/j.cellsig.2008.04.014-
hcfmusp.relation.referenceDavies KJA, 2000, IUBMB LIFE, V50, P279, DOI 10.1080/15216540051081010-
hcfmusp.relation.referencePalomino A, 2006, SCHIZOPHR RES, V86, P321, DOI 10.1016/j.schres.2006.05.028-
hcfmusp.relation.referenceKnijff EM, 2007, BIPOLAR DISORD, V9, P743, DOI 10.1111/j.1399-5618.2007.00444.x-
hcfmusp.relation.referenceSoreca I, 2009, DEPRESS ANXIETY, V26, P73, DOI 10.1002/da.20521-
hcfmusp.relation.referenceFinkel T, 2000, NATURE, V408, P239, DOI 10.1038/35041687-
hcfmusp.relation.referencePandey GN, 2010, J PSYCHIATR RES, V44, P143, DOI 10.1016/j.jpsychires.2009.07.009-
hcfmusp.relation.referenceGoldstein BI, 2009, J CLIN PSYCHIAT, V70, P1078, DOI 10.4088/JCP.08r04505-
hcfmusp.relation.referenceWang HY, 2009, J MOL MED-JMM, V87, P435, DOI 10.1007/s00109-009-0445-4-
hcfmusp.relation.referenceDe Sarno P, 2002, NEUROPHARMACOLOGY, V43, P1158, DOI 10.1016/S0028-3908(02)00215-0-
hcfmusp.relation.referenceBenes FM, 2006, MOL PSYCHIATR, V11, P241, DOI 10.1038/sj.mp.4001758-
hcfmusp.relation.referenceFilipowicz W, 2008, NAT REV GENET, V9, P102, DOI 10.1038/nrg2290-
hcfmusp.relation.referenceLogan CY, 2004, ANNU REV CELL DEV BI, V20, P781, DOI 10.1146/annurev.cellbio.20.010403.113126-
hcfmusp.relation.referenceSilva R, 2008, NEUROSCIENCE, V152, P656, DOI 10.1016/j.neuroscience.2007.12.026-
hcfmusp.relation.referenceAndreazza AC, 2007, J PSYCHIATR RES, V41, P523, DOI 10.1016/j.jpsychires.2006.07.013-
hcfmusp.relation.referenceGrassi-Oliveira R, 2009, PSYCHIAT CLIN NEUROS, V63, P202, DOI 10.1111/j.1440-1819.2008.01918.x-
hcfmusp.relation.referenceDrexhage RC, 2010, EXPERT REV NEUROTHER, V10, P59, DOI [10.1586/ern.09.144, 10.1586/ERN.09.144]-
hcfmusp.relation.referenceWodarz A, 1998, ANNU REV CELL DEV BI, V14, P59, DOI 10.1146/annurev.cellbio.14.1.59-
hcfmusp.relation.referenceBrietzke E, 2008, PROG NEURO-PSYCHOPH, V32, P1355, DOI 10.1016/j.pnpbp.2008.01.006-
hcfmusp.relation.referenceKlein PS, 1996, P NATL ACAD SCI USA, V93, P8455, DOI 10.1073/pnas.93.16.8455-
hcfmusp.relation.referenceMalhi GS, 2009, DRUGS, V69, P2063, DOI 10.2165/11318850-000000000-00000-
hcfmusp.relation.referenceInkster B, 2009, ARCH GEN PSYCHIAT, V66, P721, DOI 10.1001/archgenpsychiatry.2009.70-
hcfmusp.relation.referenceManji HK, 1999, J CLIN PSYCHIAT, V60, P27-
hcfmusp.relation.referenceGoto Y, 2010, BIOL PSYCHIAT, V67, P199, DOI 10.1016/j.biopsych.2009.08.026-
hcfmusp.relation.referenceMikels AJ, 2006, ONCOGENE, V25, P7461, DOI 10.1038/sj.onc.1210053-
hcfmusp.relation.referenceShoval G, 2005, EUR NEUROPSYCHOPHARM, V15, P319, DOI 10.1016/j.euroneuro.2004.12.005-
hcfmusp.relation.referencePereira CP, 2009, CURR ATHEROSCLER REP, V11, P236, DOI 10.1007/s11883-009-0036-4-
hcfmusp.relation.referenceReischl J, 2007, J INVEST DERMATOL, V127, P163, DOI 10.1038/sj.jid.5700488-
hcfmusp.relation.referenceTramontina JF, 2009, NEUROSCI LETT, V452, P111, DOI 10.1016/j.neulet.2009.01.028-
hcfmusp.relation.referenceRajkowska G, 1999, BIOL PSYCHIAT, V45, P1085, DOI 10.1016/S0006-3223(99)00041-4-
hcfmusp.relation.referenceWallingford JB, 2001, INT J DEV BIOL, V45, P225-
hcfmusp.relation.referenceCoryell W, 2009, BIPOLAR DISORD, V11, P77, DOI 10.1111/j.1399-5618.2009.00712.x-
hcfmusp.relation.referenceShimogori T, 2004, J COMP NEUROL, V473, P496, DOI 10.1002/cne.20135-
hcfmusp.relation.referenceHooper C, 2007, EUR J NEUROSCI, V25, P81, DOI 10.1111/j.1460-9568.2006.05245.x-
hcfmusp.relation.referenceTakeichi M, 2005, TRENDS CELL BIOL, V15, P216, DOI 10.1016/j.tcb.2005.02.002-
hcfmusp.relation.referenceToledo EM, 2010, MOL PSYCHIATR, V15, P272, DOI 10.1038/mp.2009.72-
hcfmusp.relation.referenceBrietzke E, 2009, J AFFECT DISORDERS, V116, P214, DOI 10.1016/j.jad.2008.12.001-
hcfmusp.relation.referenceCunha ABM, 2006, NEUROSCI LETT, V398, P215, DOI 10.1016/j.neulet.2005.12.085-
hcfmusp.relation.referenceDrevets WC, 1997, NATURE, V386, P824, DOI 10.1038/386824a0-
hcfmusp.relation.referenceKozlovsky N, 2000, AM J PSYCHIAT, V157, P831, DOI 10.1176/appi.ajp.157.5.831-
hcfmusp.relation.referenceBielecka AM, 2008, PHARMACOL REP, V60, P771-
hcfmusp.relation.referenceChen G, 1999, PSYCHOSOM MED, V61, P599-
hcfmusp.relation.referenceDechant G, 2002, ADV EXP MED BIOL, V513, P303-
hcfmusp.relation.referenceGazalle FK, 2006, REV BRAS PSIQUIATR, V28, P82, DOI 10.1590/S1516-44462006000100017-
hcfmusp.relation.referenceGomez-Sintes R, 2010, J CLIN INVEST, V120, P2432, DOI 10.1172/JCI37873-
hcfmusp.relation.referenceKaidanovich-Beilin O, 2004, BIOL PSYCHIAT, V55, P781, DOI 10.1016/j.biopsych.2004.01.008-
hcfmusp.relation.referenceKapczinski Flavio, 2008, Expert Rev Neurother, V8, P1101, DOI 10.1586/14737175.8.7.1101-
hcfmusp.relation.referenceLesort M, 1999, J NEURAL TRANSM, V106, P1217, DOI 10.1007/s007020050235-
hcfmusp.relation.referenceLi X, 2004, NEUROPSYCHOPHARMACOL, V29, P137-
hcfmusp.relation.referenceManji HK, 1999, BIOL PSYCHIAT, V46, P929, DOI 10.1016/S0006-3223(99)00165-1-
hcfmusp.relation.referenceMarques AH, 2007, REV BRAS PSIQUIATR, V29, pS27, DOI 10.1590/S1516-44462007000500006-
hcfmusp.relation.referenceMensulam MM, 1999, NEURON, V24, P521-
hcfmusp.relation.referenceMhyre RT, 2008, NEUROBIOL AGING, V29, P1631-
hcfmusp.relation.referenceMonti Barbara, 2009, Curr Mol Pharmacol, V2, P95-
hcfmusp.relation.referenceMoon Randall T, 2004, Nat Rev Genet, V5, P691, DOI 10.1038/nrg1427-
hcfmusp.relation.referenceOrtiz-Dominguez A, 2007, BIPOLAR DISORD, V9, P596, DOI 10.1111/j.1399-5618.2007.00493.x-
hcfmusp.relation.referencePeifer M, 2000, SCIENCE, V287, P1606, DOI 10.1126/science.287.5458.1606-
hcfmusp.relation.referenceSaus E, 2010, GENES BRAIN BEHAV-
hcfmusp.relation.referenceSchou M, 1997, ARCH GEN PSYCHIAT, V54, P9-
hcfmusp.relation.referenceShimshoni JA, 2007, MOL PHARMACOL, V71, P884, DOI 10.1124/mol.106.030601-
hcfmusp.relation.referenceSIES H, 1991, AM J MED, V91, pS31, DOI 10.1016/0002-9343(91)90281-2-
hcfmusp.relation.referenceSoares JC, 1998, NEUROPSYCHOPHARMACOL, V19, P167, DOI 10.1016/S0893-133X(98)00022-0-
hcfmusp.relation.referenceTissir F, 2006, EUR J NEUROSCI, V23, P597, DOI 10.1111/j.1460-9568.2006.04596.x-
hcfmusp.relation.referenceTolwinski NS, 2004, TRENDS GENET, V20, P1-
hcfmusp.relation.referenceVasconcellos APS, 2003, PHYSIOL BEHAV, V79, P143, DOI 10.1016/S0031-9384(03)00113-6-
hcfmusp.relation.referenceWood GE, 2004, P NATL ACAD SCI USA, V101, P3973, DOI 10.1073/pnas.0400208101-
hcfmusp.relation.referenceWOODGETT JR, 2001, SCI STKE, V100, pRE12-
hcfmusp.relation.referenceZhou L, 2009, NEUROPSYCHOPHARMACOL, V34, P1395-
dc.description.indexMEDLINE-
hcfmusp.citation.scopus17-
hcfmusp.scopus.lastupdate2024-04-12-
Appears in Collections:

Artigos e Materiais de Revistas Científicas - FM/MPS
Departamento de Psiquiatria - FM/MPS

Artigos e Materiais de Revistas Científicas - LIM/21
LIM/21 - Laboratório de Neuroimagem em Psiquiatria


Files in This Item:
File Description SizeFormat 
art_HU_The_role_of_Wnt_signaling_and_its_interaction_2011.PDF
  Restricted Access		publishedVersion (English)1.71 MBAdobe PDFView/Open Request a copy
Show simple item record

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.