Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorFERRARI, Carla Maria Maluf-
dc.contributor.authorSOUSA, Regina Marcia Cardoso de-
dc.contributor.authorCASTRO, Luiz H. M.-
dc.identifier.citationSEIZURE-EUROPEAN JOURNAL OF EPILEPSY, v.22, n.5, p.384-389, 2013-
dc.description.abstractPurpose: To investigate factors associated with treatment non-adherence in Brazilian patients with epilepsy. Methods: Prospective cross-sectional study. We evaluated 385 epilepsy outpatients in a tertiary referral center, 18 years or older, literate, without cognitive impairment or active psychiatric disorders, who were independent in daily living activities. Data were analyzed with correlation tests and conjoint analysis using multivariate logistic regression. Results: Non-adherence rate, measured by the Morisky-Green Test, was 66.2%, a moderate-to-low adherence level. Non-adherence was higher in men, in younger patients and in patients with uncontrolled seizures. Increasing treatment complexity was also associated with decreased treatment adherence. Conclusion: Strategies designed to improve treatment adherence should address peculiarities associated with younger ages and male gender. Physicians should be made aware that prescription of less complex treatment regimens may result in better treatment adherence, and, therefore, better seizure control. The challenge in adjusting AED treatment in this population is to minimize treatment complexity, thus increasing chances for treatment adherence.-
dc.publisherW B SAUNDERS CO LTD-
dc.relation.ispartofSeizure-European Journal of Epilepsy-
dc.subjectTreatment adherence-
dc.subjectAntiepileptic drug-
dc.subjectMorisky-Green Test-
dc.subjectTreatment Complexity Index-
dc.subject.othermedication compliance-
dc.subject.otherantiepileptic drugs-
dc.subject.othercomplexity index-
dc.subject.otherseizure control-
dc.titleFactors associated with treatment non-adherence in patients with epilepsy in Brazil-
dc.rights.holderCopyright W B SAUNDERS CO LTD-
dc.subject.wosClinical Neurology-
dc.type.categoryoriginal article-
dc.type.versionpublishedVersion-, Carla Maria Maluf:Sao Camilo Univ Ctr, Sao Paulo, Brazil-, Regina Marcia Cardoso de:EEUSP, Dept Med Surg Nursing, Sao Paulo, Brazil-
hcfmusp.relation.referenceAraujo MFM, 2010, ESC ANNA NERY REV EN, V14, P361, DOI 10.1590/S1414-81452010000200021-
hcfmusp.relation.referenceBarbosa RGB, 2006, REV BRAS HIPERTENS, V13, P35-
hcfmusp.relation.referenceBen-Menachem E, 2010, EPILEPSY BEHAV, V18, P24, DOI 10.1016/j.yebeh.2010.04.001-
hcfmusp.relation.referenceBrown I, 2009, EPILEPSY BEHAV, V16, P634, DOI 10.1016/j.yebeh.2009.09.014-
hcfmusp.relation.referenceChen HF, 2010, EPILEPSY BEHAV, V19, P43, DOI 10.1016/j.yebeh.2010.06.007-
hcfmusp.relation.referenceColombrini Maria Rosa Ceccato, 2006, Rev Esc Enferm USP, V40, P576, DOI 10.1590/S0080-62342006000400018-
hcfmusp.relation.referenceCommission on Classification and Terminology of the International League Against Epilepsy, 1989, EPILEPSIA, V30, P389-
hcfmusp.relation.referenceCornélio Rita de Cássia Azevedo Couto, 2009, Arq. Gastroenterol., V46, P183, DOI 10.1590/S0004-28032009000300008-
hcfmusp.relation.referenceCosta-Junior FM, 2009, PSICOL TEORIA PESQ, V25, P55-
hcfmusp.relation.referenceCramer JA, 2002, EPILEPSY BEHAV, V3, P338, DOI 10.1016/S1525-5050(02)00037-9-
hcfmusp.relation.referenceSouza Dewulf Nathalie de Lourdes, 2006, Revista Brasileira de Ciencias Farmaceuticas, V42, P575-
hcfmusp.relation.referenceDillorio C, 2003, J NEUROSCIENCE NURSI, V35, P155-
hcfmusp.relation.referenceDillorio C, 2004, EPILEPSY BEHAV, V5, P926-
hcfmusp.relation.referenceDilorio C, 2003, J NEUROSCI NURS, V35, P155-
hcfmusp.relation.referenceDilorio C, 1991, RES NURS HLTH, V14, P329-
hcfmusp.relation.referenceDoughty J, 2003, EPILEPSY BEHAV, V4, P710, DOI 10.1016/j.yebeh.2003.08.013-
hcfmusp.relation.referenceElger CE, 2008, EPILEPSY BEHAV, V12, P501, DOI 10.1016/j.yebeh.2008.01.003-
hcfmusp.relation.referenceFaught E, 2012, EPILEPSY BEHAV, V25, P297, DOI 10.1016/j.yebeh.2012.08.027-
hcfmusp.relation.referenceFerrari CMM, 2011, EPILEPSY BEHAV, V21, P467, DOI 10.1016/j.yebeh.2011.04.054-
hcfmusp.relation.referenceFigueiredo RM, 2001, REV LAT-AM ENFERM, V9, P50-
hcfmusp.relation.referenceGagne C, 2005, PSYCHOL HEALTH, V20, P803, DOI 10.1080/14768320500386441-
hcfmusp.relation.referenceGeorge J, 2004, ANN PHARMACOTHER, V38, P1369, DOI 10.1345/aph.1D479-
hcfmusp.relation.referenceGomes R, 2007, CAD SAUDE PUBLICA, V23, P564-
hcfmusp.relation.referenceHandoko KB, 2008, EPILEPSY BEHAV, V13, P545, DOI 10.1016/j.yebeh.2008.04.007-
hcfmusp.relation.referenceHenriques MAPH, 2006, THESIS ESCOLA SUPERI-
hcfmusp.relation.referenceHinkin CH, 2002, NEUROLOGY, V59, P1955-
hcfmusp.relation.referenceHovinga CA, 2008, EPILEPSY BEHAV, V13, P316, DOI 10.1016/j.yebeh.2008.03.009-
hcfmusp.relation.referenceJones RM, 2006, SEIZURE-EUR J EPILEP, V15, P504, DOI 10.1016/j.seizure.2006.06.003-
hcfmusp.relation.referenceManjunath R, 2009, EPILEPSY BEHAV, V14, P372, DOI 10.1016/j.yebeh.2008.12.006-
hcfmusp.relation.referenceMarques PAC, 2008, ACTA PAUL ENFERM, V21, P323, DOI 10.1590/S0103-21002008000200015-
hcfmusp.relation.referenceMartins Heloise Helena, 2009, J. epilepsy clin. neurophysiol., V15, P192, DOI 10.1590/S1676-26492009000400010-
hcfmusp.relation.referenceMcAuley JW, 2008, EPILEPSY BEHAV, V13, P637, DOI 10.1016/j.yebeh.2008.07.005-
hcfmusp.relation.referenceMedeiros ARC, 2006, THESIS U FEDERAL PAR-
hcfmusp.relation.referenceMeyer AC, 2010, B WORLD HEALTH ORGAN, V88, P260, DOI [10.2471/BLT.09.064147, 10.1590/S0042-96862010000400011]-
hcfmusp.relation.referenceMORISKY DE, 1986, MED CARE, V24, P67, DOI 10.1097/00005650-198601000-00007-
hcfmusp.relation.referenceRidsdale L, 2003, SEIZURE-EUR J EPILEP, V12, P69, DOI 10.1016/S1059-1311(02)00178-4-
hcfmusp.relation.referenceRubin RR, 2005, AM J MED, V118, P27, DOI 10.1016/j.amjmed.2005.04.012-
hcfmusp.relation.referenceSilva NN, 2001, AMOSTRAGEM PROBABILI-
hcfmusp.relation.referenceSinaa Al-Aqeel, COCHRANE LIB, DOI [10.1002/14651858.CD008312.pub1, DOI 10.1002/14651858.CD008312.PUB]-
hcfmusp.relation.referenceSmithson WH, 2012, EPILEPSY BEHAV, V24, P49, DOI 10.1016/j.yebeh.2012.02.015-
hcfmusp.relation.referenceSpecht U, 2003, EPILEPSY BEHAV, V4, P487, DOI 10.1016/S1525-5050(03)00151-3-
hcfmusp.relation.referenceStrelec MAAM, 2003, ARQ BRAS CARDIOL, V81, P343-
hcfmusp.relation.referenceWilliams AB, 1999, NURS CLIN N AM, V34, P113-
hcfmusp.relation.referenceYeager KA, 2005, EPILEPSY BEHAV, V7, P679, DOI 10.1016/j.yebeh.2005.07.008-
hcfmusp.relation.referenceWHO, 2003, ADH LONG TERM THER E-
Appears in Collections:

Artigos e Materiais de Revistas Científicas - HC/ICHC
Instituto Central - HC/ICHC

Artigos e Materiais de Revistas Científicas - HC/InCor
Instituto do Coração - HC/InCor

Artigos e Materiais de Revistas Científicas - LIM/45
LIM/45 - Laboratório de Fisiopatologia Neurocirúrgica

Files in This Item:
File Description SizeFormat 
  Restricted Access
publishedVersion (English)249.55 kBAdobe PDFView/Open Request a copy

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.