Prevalence of anxiety, depression and quality of life in HTLV-1 infected patients

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dc.contributor Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP GASCON, Maria Rita Polo FMUSP-HC
CAPITAO, Claudio Garcia
NOGUEIRA-MARTINS, Maria Cezira Fantini
SMID, Jerusa
OLIVEIRA, Augusto Cesar Penalva de 2011
dc.identifier.citation BRAZILIAN JOURNAL OF INFECTIOUS DISEASES, v.15, n.6, p.578-582, 2011
dc.identifier.issn 1413-8670
dc.description.abstract The HAM/TSP caused by HTLV-1 infection usually affects patients to disabling states, and sometimes can lead them to paraplegia presenting symptoms of depression and anxiety, impacting on quality of life. Objective: The purpose of this study was to evaluate the frequency of depression and anxiety and its impact on quality of life in HTLV-1-infected TSP/HAM patients. Material and Methods: This was a cross-sectional study including 67 asymptomatic (control group) and 63 with TSP/HAM subjects. The instruments used were a demographic questionnaire, scales for anxiety and depression diagnosis (BDI and BAI), questionnaire for the assessment of Quality of Life of the World Health Organization (WHOQOL-Brief) and neurological scale to measure the disability level (Osame's Disability Status Scale). All patients had HTLV-I diagnosis by serological and molecular approaches, monitored at Instituto de Infectologia Emilio Ribas from May 2008 to July 2009. Data were analyzed statistically by frequencies, the Mann-Whitney test and the Spearman correlation test. Data among groups were analyzed and correlated with functional and severity aspects. Results: The results showed that patients with HAM/TSP compared to asymptomatic carriers had higher rates of depression (p < 0.001) and anxiety (p < 0.001), and impairment on quality of life in the areas of: dissatisfaction with health (p < 0.001), physical (p < 0.001) and the environment (p = 0.003). The main factors that correlated with levels of depression and anxiety and the domains of the WHOQOL-brief were: education, family income and social class. Conclusion: A well conducted evaluation and counseling may help in treatment, for a better quality of life of these patients.
dc.description.sponsorship · FAPESP e Coordenadoria de Controle de Doencas CCD/SES-SP
dc.language.iso eng
dc.publisher CONTEXTO
dc.relation.ispartof Brazilian Journal of Infectious Diseases
dc.rights openAccess
dc.subject anxiety; depression; quality of life; human T-lymphotropic virus 1
dc.subject.other virus type-i; brazil
dc.title Prevalence of anxiety, depression and quality of life in HTLV-1 infected patients
dc.type article
dc.rights.holder Copyright CONTEXTO LIM/56
dc.identifier.pmid 22218518
dc.type.category original article
dc.type.version publishedVersion GASCON, Maria Rita Polo:HC:ICHC CASSEB, Jorge:IMT:IMT · NOGUEIRA-MARTINS, Maria Cezira Fantini:Inst Saude Sao Paulo, Sao Paulo, SP, Brazil
· SMID, Jerusa:Univ Sao Paulo, Inst Infectol Emilio Ribas, Hosp Clin, Sao Paulo, SP, Brazil
· OLIVEIRA, Augusto Cesar Penalva de:Santa Casa de Misericordia Sao Paulo, Inst Infectol Emilio Ribas, Sao Paulo, SP, Brazil; Univ Estadual Campinas, UNICAMP, BR-13081970 Campinas, SP, Brazil 2-s2.0-84855976310 WOS:000298304300012 SALVADOR BRAZIL
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dc.description.index MEDLINE
hcfmusp.citation.scopus 15 Brasil
hcfmusp.scopus.lastupdate 2021-07-14

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