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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorFRANCA, Camila Maria Paiva-
dc.contributor.authorSALLUM, Adriana Maluf Elias-
dc.contributor.authorBRAGA, Alfesio Luis Ferreira-
dc.contributor.authorSTRUFALDI, Fernando Louzada-
dc.contributor.authorSILVA, Clovis Artur Almeida-
dc.contributor.authorFARHAT, Sylvia Costa Lima-
dc.date.accessioned2018-03-06T15:18:51Z-
dc.date.available2018-03-06T15:18:51Z-
dc.date.issued2018-
dc.identifier.citationJOURNAL OF RHEUMATOLOGY, v.45, n.2, p.248-256, 2018-
dc.identifier.issn0315-162X-
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/25639-
dc.description.abstractObjective. To evaluate exposure to environmental factors inhaled during pregnancy and after birth until juvenile idiopathic arthritis (JIA) diagnosis among residents of a large city. Methods. This is an exploratory case-control study that consists of 66 patients with JIA and 124 healthy controls matched by age and sex, living in the Sao Paulo, Brazil, metropolitan area until JIA diagnosis, and whose mothers had resided in this region during pregnancy. A structured and reliable questionnaire (k index for test-retest was 0.80) assessed demographic data, gestational and perinatal-related factors, and exposure to inhalable environmental elements during pregnancy and after birth (occupational exposure to inhalable particles and/or volatile vapor, exposure to cigarette smoke, and the presence of industrial activities or gas stations near the home, work, daycare, or school). Tropospheric pollutants included particulate matter (PM10), sulfur dioxide (SO2), nitrogen dioxide (NO2), ozone (O-3), and carbon monoxide (CO). Results. During pregnancy, intrauterine cigarette smoke exposure (OR 3.43, 95% CI 1.45-8.12, p = 0.005) and maternal occupational exposure (OR 13.69, 95% CI 4.4-42.3, p < 0.001) were significant independent risk factors for JIA diagnosis. In contrast, maternal employment (OR 0.06, 95% CI 0.02-0.2, p < 0.001) and ideal maternal weight gain (OR 0.36, 95% CI 0.2-0.8, p = 0.017) presented negative associations. Secondhand smoke exposure from birth to JIA diagnosis (OR 3.6, 95% CI 1.8-7.3, p < 0.001) and exposure to O-3 during the second year of life (OR 2.76, 95% CI 1.20-6.37, p = 0.017) were independent and significant risk factors for the pathogenesis of JIA. Conclusion. In our study, cigarette smoke exposure (intrauterine and after birth), exposure to O-3 in the second year of life, and maternal occupational exposure were identified as potential risk factors for JIA, warranting further study.-
dc.description.sponsorshipConselho Nacional de Desenvolvimento Cientifico e Tecnologico [CNPq 472155/2012-1, 302724/2011-7]-
dc.description.sponsorshipFederico Foundation-
dc.description.sponsorshipNucleo de Apoio a Pesquisa ""Saude da Crianca e do Adolescente"" da USP (NAP-CriAd)-
dc.language.isoeng-
dc.publisherJ RHEUMATOL PUBL CO-
dc.relation.ispartofJournal of Rheumatology-
dc.rightsrestrictedAccess-
dc.subjectJUVENILE IDIOPATHIC ARTHRITIS-
dc.subjectENVIRONMENTAL FACTOR-
dc.subjectSMOKING-
dc.subjectAIR POLLUTION-
dc.subjectMATERNAL OCCUPATIONAL EXPOSURE-
dc.subject.otherlupus-erythematosus patients-
dc.subject.otherrheumatoid-arthritis-
dc.subject.otherparticulate matter-
dc.subject.othermaternal smoking-
dc.subject.otherdna methylation-
dc.subject.otherozone exposure-
dc.subject.otherswedish eira-
dc.subject.otherhealth-
dc.subject.otherpollutants-
dc.subject.otherbiomarkers-
dc.titleRisk Factors Associated with Juvenile Idiopathic Arthritis: Exposure to Cigarette Smoke and Air Pollution from Pregnancy to Disease Diagnosis-
dc.typearticle-
dc.rights.holderCopyright J RHEUMATOL PUBL CO-
dc.identifier.doi10.3899/jrheum.161500-
dc.identifier.pmid29142039-
dc.subject.wosRheumatology-
dc.type.categoryoriginal article-
dc.type.versionpublishedVersion-
hcfmusp.description.beginpage248-
hcfmusp.description.endpage256-
hcfmusp.description.issue2-
hcfmusp.description.volume45-
hcfmusp.origemWOS-
hcfmusp.origem.idWOS:000423828600017-
hcfmusp.origem.id2-s2.0-85041686228-
hcfmusp.publisher.cityTORONTO-
hcfmusp.publisher.countryCANADA-
hcfmusp.relation.referenceABEP, 2013, CRIT PADR CLASS EC B-
hcfmusp.relation.referenceAfridi HI, 2014, CLIN LAB, V60, P1735, DOI 10.7754/Clin.Lab.2014.131117-
hcfmusp.relation.referenceAnderson R, 2016, NICOTINE TOB RES, V18, P1556, DOI 10.1093/ntr/ntw030-
hcfmusp.relation.referenceApte K, 2016, F1000RES, V5-
hcfmusp.relation.referenceBernatsky S, 2016, ENVIRON RES, V146, P85, DOI 10.1016/j.envres.2015.12.021-
hcfmusp.relation.referenceBreton CV, 2014, PLOS ONE, V9, DOI 10.1371/journal.pone.0099716-
hcfmusp.relation.referenceBrook RD, 2010, CIRCULATION, V121, P2331, DOI 10.1161/CIR.0b013e3181dbece1-
hcfmusp.relation.referenceCalderon-Garciduenas L, 2008, INHAL TOXICOL, V20, P499, DOI [10.1080/08958370701864797, 10.1080/08958370701864797 ]-
hcfmusp.relation.referenceCenters for Disease Control and Prevention (CDC), ALC US YOUR HLTH-
hcfmusp.relation.referenceCETESB, RED MON-
hcfmusp.relation.referenceChang KH, 2016, ENVIRON INT, V94, P495, DOI 10.1016/j.envint.2016.06.008-
hcfmusp.relation.referenceChuang GC, 2009, AM J PHYSIOL-LUNG C, V297, pL209, DOI 10.1152/ajplung.00102.2009-
hcfmusp.relation.referenceDe Roos AJ, 2014, ENVIRON HEALTH PERSP, V122, P1075, DOI 10.1289/ehp.1307413-
hcfmusp.relation.referenceDi Giuseppe D, 2014, ARTHRITIS RES THER, V16, DOI 10.1186/ar4498-
hcfmusp.relation.referenceEllis JA, 2012, PEDIATR RHEUMATOL, V10, DOI 10.1186/1546-0096-10-37-
hcfmusp.relation.referenceElvidge T, 2013, J ENVIRON SCI HEAL C, V31, P1, DOI 10.1080/10590501.2013.763575-
hcfmusp.relation.referenceFarhat J, 2016, REV BRAS REUMATOL, V56, P212, DOI 10.1016/j.rbre.2015.08.005-
hcfmusp.relation.referenceFarhat SCL, 2011, AUTOIMMUN REV, V11, P14, DOI 10.1016/j.autrev.2011.06.008-
hcfmusp.relation.referenceFernandes EC, 2015, ARTHRIT CARE RES, V67, P1609, DOI 10.1002/acr.22603-
hcfmusp.relation.referenceGoodman JE, 2015, CRIT REV TOXICOL, V45, P412, DOI 10.3109/10408444.2015.1031371-
hcfmusp.relation.referenceGryparis A, 2004, AM J RESP CRIT CARE, V170, P1080, DOI 10.1164/rccm.200403-333OC-
hcfmusp.relation.referenceGuimarães Mariana Tavares, 2011, Rev. bras. epidemiol., V14, P598, DOI 10.1590/S1415-790X2011000400007-
hcfmusp.relation.referenceHart JE, 2013, ARTHRIT CARE RES, V65, P1190, DOI 10.1002/acr.21975-
hcfmusp.relation.referenceHart JE, 2013, ANN RHEUM DIS, V72, P888, DOI 10.1136/annrheumdis-2012-201587-
hcfmusp.relation.referenceHart JE, 2009, ENVIRON HEALTH PERSP, V117, P1065, DOI 10.1289/ehp.0800503-
hcfmusp.relation.referenceJaakkola JJ, 2005, INT J EPIDEMIOL, V34, P664, DOI 10.1093/ije/dyi006-
hcfmusp.relation.referenceJoubert BR, 2012, ENVIRON HEALTH PERSP, V120, P1425, DOI 10.1289/ehp.1205412-
hcfmusp.relation.referenceKarlson EW, 1999, ARTHRITIS RHEUM, V42, P910, DOI 10.1002/1529-0131(199905)42:5<910::AID-ANR9>3.3.CO;2-4-
hcfmusp.relation.referenceKnopik VS, 2012, DEV PSYCHOPATHOL, V24, P1377, DOI 10.1017/S0954579412000776-
hcfmusp.relation.referenceLee KWK, 2015, ENVIRON HEALTH PERSP, V123, P193, DOI 10.1289/ehp.1408614-
hcfmusp.relation.referenceMiligi L, 2013, OCCUP ENVIRON MED, V70, P648, DOI 10.1136/oemed-2012-100951-
hcfmusp.relation.referenceMorales E, 2016, INT J EPIDEMIOL, V45, P1644, DOI 10.1093/ije/dyw196-
hcfmusp.relation.referenceThe National Academies Press, 2009, WEIGHT GAIN PREGNANC-
hcfmusp.relation.referenceOrione MAM, 2014, ARTHRIT CARE RES, V66, P1571, DOI 10.1002/acr.22358-
hcfmusp.relation.referencePerez-Padilla R, 2010, INT J TUBERC LUNG D, V14, P1079-
hcfmusp.relation.referencePetty RE, 2004, J RHEUMATOL, V31, P390-
hcfmusp.relation.referenceShea AK, 2008, NICOTINE TOB RES, V10, P267, DOI 10.1080/14622200701825908-
hcfmusp.relation.referenceShenoi S, 2016, ARTHRIT CARE RES, V68, P1186, DOI 10.1002/acr.22806-
hcfmusp.relation.referenceShenoi S, 2015, ARTHRIT CARE RES, V67, P725, DOI 10.1002/acr.22471-
hcfmusp.relation.referenceSilva Clovis Artur A., 2004, J. Pediatr. (Rio J.), V80, P517, DOI 10.1590/S0021-75572004000800015-
hcfmusp.relation.referenceStolt P, 2005, ANN RHEUM DIS, V64, P582, DOI 10.1136/ard.2004.022053-
hcfmusp.relation.referenceSugiyama D, 2010, ANN RHEUM DIS, V69, P70, DOI 10.1136/ard.2008.096487-
hcfmusp.relation.referenceVidotto JP, 2012, LUPUS, V21, P526, DOI 10.1177/0961203312437806-
hcfmusp.relation.referenceWatkinson WP, 2001, ENVIRON HEALTH PERSP, V109, P539, DOI 10.2307/3454666-
hcfmusp.relation.referenceWHO, 2016, AMB AIR POLL GLOB AS-
hcfmusp.relation.referenceYamashita E, 2013, REV BRAS REUMATOL, V53, P542, DOI [10.1016/j.rbre.2013.04.005, 10.1016/j.rbr.2013.04.005]-
hcfmusp.relation.referenceZeft AS, 2016, CLIN EXP RHEUMATOL, V34, P946-
hcfmusp.relation.referenceZeft AS, 2009, CLIN EXP RHEUMATOL, V27, P877-
hcfmusp.relation.referenceZhou YF, 2014, PLOS ONE, V9, DOI 10.1371/journal.pone.0110466-
dc.description.indexMEDLINE-
dc.identifier.eissn1499-2752-
hcfmusp.citation.scopus12-
hcfmusp.scopus.lastupdate2022-09-23-
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