Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/2724
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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorFIGUEIREDO, C. P.-
dc.contributor.authorLOPES, J. B.-
dc.contributor.authorCAPARBO, V. F.-
dc.contributor.authorTAKAYAMA, L.-
dc.contributor.authorBONFA, E. D.-
dc.contributor.authorPEREIRA, R. M.-
dc.date.accessioned2013-10-11T21:16:40Z-
dc.date.available2013-10-11T21:16:40Z-
dc.date.issued2012-
dc.identifier.citationOSTEOPOROSIS INTERNATIONAL, v.23, suppl.4, p.S496-S496, 2012-
dc.identifier.issn0937-941X-
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/2724-
dc.description.abstractAims: To analyze abdominal aortic calcification (AAC) and its possible association with bone metabolism parameters as well as others clinical and laboratory data in a São Paulo community-dwelling elderly (SPAH). Methods: This cross-sectional study included 815 subjects ≥ 65 years old. The risk factors for osteoporosis and cardiovascular disease as well as a wide array of demographic and lifestyle characteristics were collected using a standardized questionnaire. BMD was measured by DXA. Kauppila’ s method was used to quantify the AAC score (AACS) by spine X-rays. Laboratory analyses were also performed. Results: AAC was observed in 63.2 % of subjects with a mean AACS of 4.68±5.88. AACS was directly correlated with age, phosphorus, LDL-cholesterol, triglycerides, and inversely correlated with BMI, femoral neck BMD and total femur BMD (p<0.05). Regarding binary variables, the AACS was associated with previous fragility fractures, current smoking, low physical activity, falls and arterial hypertension (p<0.05). Multiple lin-ear regression analysis demonstrated that the AACS was positively associated with phosphate (p=0.005) and negatively associated with total femur BMD (p<0.001) after adjusting by age, triglycerides, current smoking, arterial hypertension and LDL-cholesterol. An increased of AACS was observed with the elevation of serum phosphorus levels [£ 2.4 mg/dL: AACS 01.9 (SD:3.9); 2.5-3.5 mg/dL: AACS04.5 (SD:5.6)and >3.5 mg/dL: AACS05.3 (SD:6.3), p=0.003]. Conclusion: Our study identified serum phosphate and hip BMD as additional players in the complex process of vascular calcification outside the setting of kidney failure in a community-dwelling elderly and extended the previous observations of well-known risk factors for cardiovascular disease.-
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
dc.language.isoeng-
dc.publisherSPRINGER LONDON LTD-
dc.relation.ispartofOsteoporosis International-
dc.rightsrestrictedAccess-
dc.titleSERUM PHOSPHATE AND HIP BONE MINERAL DENSITY AS ADDITIONAL FACTORS IN VASCULAR CALCIFICATION IN A COMMUNITY-DWELLING: SAO PAULO AGEING HEALTHY STUDY (SPAH)-
dc.typeconferenceObject-
dc.rights.holderCopyright SPRINGER LONDON LTD-
dc.description.conferencedateMAY 24-27, 2012-
dc.description.conferencelocalSao Paulo, BRAZIL-
dc.description.conferencenameIOF Regionals 1st Latin America Osteoporosis Meeting-
dc.subject.wosEndocrinology & Metabolism-
dc.type.categorymeeting abstract-
dc.type.versionpublishedVersion-
hcfmusp.description.beginpageS496-
hcfmusp.description.endpageS496-
hcfmusp.description.issuesuppl 4-
hcfmusp.description.volume23-
hcfmusp.origemWOS-
hcfmusp.origem.idWOS:000309260800059-
hcfmusp.publisher.cityLONDON-
hcfmusp.publisher.countryENGLAND-
dc.description.indexMEDLINE-
hcfmusp.remissive.sponsorshipCAPES-
hcfmusp.remissive.sponsorshipFAPESP-
Appears in Collections:

Comunicações em Eventos - FM/MCM
Departamento de Clínica Médica - FM/MCM

Comunicações em Eventos - HC/ICHC
Instituto Central - HC/ICHC

Comunicações em Eventos - LIM/17
LIM/17 - Laboratório de Investigação em Reumatologia


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