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Title: Creatine Supplementation Increases Physical Function And Lower-limb Lean Mass In Osteoarthritis: A Role For Myostatin?
Authors: SOLIS, Marina Y.NEVES JR., ManoelARTIOLI, Guilherme GianniniROCHEL, HamiltonFULLER, RicardoBENATTI, Fabiana BragaPINTO, Ana Lucia De SaLIMA, Fernanda RodriguesLANCHA JR., Antonio HerbertBONFA, EloisaGUALANO, Bruno
Citation: MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, v.44, suppl.2, p.605-606, 2012
Abstract: PURPOSE: The purpose of this study was to determine the effects of Cr supplementation on vertical jump and sprint performance during 4 weeks of plyometric training. METHODS: Using a randomized, double-blind design, subjects were assigned to receive either Cr or placebo (Pl) for 4-weeks. A total of 13 subjects completed the study (6 = Pl, 7 = Cr). Data was collected at baseline (T0), post-loading (T1), and post-maintenance (T2). Measures included body weight, height, bioelectrical impedance analysis (BIA), single and multiple vertical jump performance, (4 x 10m) shuttle sprint time, and anaerobic power using a 30-s Wingate trial. BIA was used to determine total body water (TBW). Subjects were instructed to maintain a normal diet and to follow a training program designed for this study. Data was analyzed using repeated measures two-way ANOVA for differences (time x treatment) and t-tests to assess the absolute change in values for all measures. RESULTS: The interaction over time between treatment groups revealed significantly greater increases in body weight, body mass index (BMI), and average Wingate power (p < 0.05) for the Cr group. Using the absolute change in values, t-tests revealed significant increases in body weight (mean gain = 1.0 kg, p = 0.003) and TBW (mean gain = 0.4 kg, p = 0.03) in the Cr group compared to Pl after T1. No significant changes in single jump height or shuttle sprint time were seen were seen with either Cr or Pl groups. Average Wingate power tended to increase from T0 to T2 in the Cr group (mean % change = +5.9%) with no change in the Pl group (p = 0.06). Average repeated vertical jump height from T0 to T2 tended to decline in the Pl (mean change = -7.5%) compared to Cr (mean change = -0.2%, p = 0.07). CONCLUSION: Although weight increased with Cr supplementation, it did not impede sprint and jump performance. Cr supplementation did tend to increase power as measured using the non-weight impacted Wingate test. Cr supplementation can be recommended to athletes wishing to increase power and weight without negatively affecting sprint and vertical jump performance.
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Comunicações em Eventos - FM/MCM
Departamento de Clínica Médica - FM/MCM

Comunicações em Eventos - HC/ICHC
Instituto Central - HC/ICHC

Comunicações em Eventos - LIM/17
LIM/17 - Laboratório de Investigação em Reumatologia

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