Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/2736
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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorSIQUEIRA, Flavia Ramos de-
dc.contributor.authorSOUZA, Regiane Machado de-
dc.contributor.authorOLIVEIRA, Ivone Braga de-
dc.contributor.authorFURUKAWA, Luzia Naoko S.-
dc.contributor.authorHEIMANN, Joel Claudio-
dc.date.accessioned2013-10-11T21:16:42Z-
dc.date.available2013-10-11T21:16:42Z-
dc.date.issued2012-
dc.identifier.citationFASEB JOURNAL, v.26, 2012-
dc.identifier.issn0892-6638-
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/2736-
dc.description.abstractThis study examined the effects of maternal low sodium intake during different periods of pregnancy on dams and male (M) and female (F) offspring. Methods: Female Wistar rats (n= 6 - 8/group) were fed low (LS - 0.15%) or normal (NS - 1.3% NaCl) sodium diet since the 1st day of gestation until delivery or LS during the 1st (LS10) or 2nd half of gestation (LS20). Results: (mean±SEM, p< 0.05): Maternal body weight (g) was lower in LS and LS20 than in NS and LS10 at the 3rd week of gestation (LS = 380±8.1; LS20 = 406±13.2; NS = 435±6.1, LS10 = 461±12.9). No difference was found in water and food intake among the groups. Also, no differences were observed in the litter size among experimental groups and no correlation betweenthe number of pups and maternal body weight at the 3rd week of gestation. At birth, body weight (g, n=14 to 27/group) (M: NS = 6.5±0.1, LS = 5.5±0.1, LS10 = 6.1±0.1, LS20 =4.8±0.1,F:NS = 6.1±0.2, LS = 5.2±0.1, LS10 = 5.6±0.1, LS20 = 4.1±0.1) and naso-anal length (cm, n=14 to 27) (M: NS = 5.1±0.02, LS = 4.9±0.03, LS10 = 5.0±0.03, LS20 = 4.6±0.03, F: NS =4.9±0.05,LS = 4.8±0.04, LS10 = 4.9±0.03, LS20 = 4.4±0.03) were lower in LS and LS20 than in NS offspring. Conclusion: Although maternal dietary intake was not influenced by dietary sodium content, maternal low sodium diet during the second half of gestation induced lower birth weight and size.-
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.language.isoeng-
dc.publisherFEDERATION AMER SOC EXP BIOL-
dc.relation.ispartofFaseb Journal-
dc.rightsrestrictedAccess-
dc.titleLow sodium intake is associated with low birth weight and size only when given in the second half of gestation-
dc.typeconferenceObject-
dc.rights.holderCopyright FEDERATION AMER SOC EXP BIOL-
dc.description.conferencedateAPR 21-25, 2012-
dc.description.conferencelocalSan Diego - CA, EUA-
dc.description.conferencenameExperimental Biology Meeting-
dc.subject.wosBiochemistry & Molecular Biology-
dc.subject.wosBiology-
dc.subject.wosCell Biology-
dc.type.categorymeeting abstract-
dc.type.versionpublishedVersion-
hcfmusp.author.externalSOUZA, Regiane Machado de:Univ Sao Paulo, Sch Med, Sao Paulo, Brazil-
hcfmusp.description.volume26-
hcfmusp.origemWOS-
hcfmusp.origem.idWOS:000310711305001-
hcfmusp.publisher.cityBETHESDA-
hcfmusp.publisher.countryUSA-
dc.description.indexMEDLINE-
hcfmusp.remissive.sponsorshipCAPES-
hcfmusp.remissive.sponsorshipFAPESP-
Appears in Collections:

Comunicações em Eventos - FM/MCM
Departamento de Clínica Médica - FM/MCM

Comunicações em Eventos - LIM/16
LIM/16 - Laboratório de Fisiopatologia Renal


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