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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorFAVERO, Serena del-
dc.contributor.authorROSCHEL, Hamilton-
dc.contributor.authorSOLIS, Marina Y.-
dc.contributor.authorHAYASHI, Ana P.-
dc.contributor.authorARTIOLI, Guilherme G.-
dc.contributor.authorOTADUY, Maria Concepcion-
dc.contributor.authorBENATTI, Fabiana B.-
dc.contributor.authorHARRIS, Roger C.-
dc.contributor.authorWISE, John A.-
dc.contributor.authorLEITE, Claudia C.-
dc.contributor.authorPEREIRA, Rosa M.-
dc.contributor.authorSA-PINTO, Ana L. de-
dc.contributor.authorLANCHA-JUNIOR, Antonio Herbert-
dc.contributor.authorGUALANO, Bruno-
dc.identifier.citationMEDICINE AND SCIENCE IN SPORTS AND EXERCISE, v.44, suppl.2, p.447-447, 2012-
dc.description.abstractPURPOSE: To investigate the effects of beta-alanine supplementation on exercise performance capacity and on the muscle carnosine content in elderly subjects. METHODS: Eighteen elderly subjects (65 ± 4 yrs) were randomly assigned to receive either beta-alanine (BA, n=12) or placebo (PL, n=6) for 12 weeks. The BA group received 3.2g of betaalanine per day (2x800mg, given 2 times per day). The PL group received the exact same amount of placebo. At baseline (PRE) and after 12 weeks (POST-12) of supplementation we assessed the muscle carnosine content and anaerobic exercise capacity. Food intake was monitored throughout the study. RESULTS: A significant increase in the muscle carnosine content of the gastrocnemius muscle was found in the BA group (+ 85.4%) when compared with the PL group (+ 7.2%) (p=0.004; ES: 1.21). The time-to-exhaustion in the TLIM test was significantly improved (p=0.05; ES: 1.71) in the BA group (+36.5%) versus the PL group (+8.6%). Similarly, time-to-exhaustion in the incremental test was also significantly increased (p=0.04; ES: 1.03) following beta-alanine supplementation (+12.2%) when compared with placebo (+0.1%). We also observed significant positive correlations between the relative change in the muscle carnosine content and the relative change in the time-to-exhaustion in the TLIM test (r=0.62; p = 0.01) and in the incremental test (r=0.48; p = 0.02). Dietary intake was unchanged. CONCLUSION: beta-alanine supplementation is effective in increasing the muscle carnosine content in healthy elderly subjects, with subsequent improvement in their exercise capacity.-
dc.relation.ispartofMedicine and Science in Sports and Exercise-
dc.titleBeta-alanine Supplementation Increases Muscle Carnosine Content And Physical Capacity In Elderly Subjects-
dc.rights.holderCopyright LIPPINCOTT WILLIAMS & WILKINS-
dc.description.conferencedateMAY 29-JUN 2, 2012-
dc.description.conferencelocalSan Francisco - CA, EUA-
dc.description.conferencename59th ACSM Annual Meeting, 3rd Exercise is Medicine-
dc.subject.wosSport Sciences-
dc.type.categorymeeting abstract-
dc.type.versionpublishedVersion-, Serena del:Univ Sao Paulo, Sch Phys Educ & Sport, Sao Paulo, Brazil-, Hamilton:Univ Sao Paulo, Sch Phys Educ & Sport, Sao Paulo, Brazil-, Marina Y.:Univ Sao Paulo, Sch Phys Educ & Sport, Sao Paulo, Brazil-, Ana P.:Univ Sao Paulo, Sch Phys Educ & Sport, Sao Paulo, Brazil-, Guilherme G.:Univ Sao Paulo, Sch Phys Educ & Sport, Sao Paulo, Brazil-, Fabiana B.:Univ Sao Paulo, Sch Phys Educ & Sport, Sao Paulo, Brazil-, Roger C.:Junipa Ltd, Newmarket, Suffolk, England-, John A.:Nat Alternat Int Inc, San Marcos, CA USA-, Antonio Herbert:Univ Sao Paulo, Sch Phys Educ & Sport, Sao Paulo, Brazil-, Bruno:Univ Sao Paulo, Sch Phys Educ & Sport, Sao Paulo, Brazil-
hcfmusp.description.issuesuppl 2-
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Comunicações em Eventos - FM/MCM
Departamento de Clínica Médica - FM/MCM

Comunicações em Eventos - FM/MDR
Departamento de Radiologia - FM/MDR

Comunicações em Eventos - HC/ICHC
Instituto Central - HC/ICHC

Comunicações em Eventos - HC/InRad
Instituto de Radiologia - HC/InRad

Comunicações em Eventos - LIM/17
LIM/17 - Laboratório de Investigação em Reumatologia

Comunicações em Eventos - LIM/44
LIM/44 - Laboratório de Ressonância Magnética em Neurorradiologia

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