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Authors: HOEFLING, DaniloCHAVANTES, Maria CristinaJULIANO, AdrianaCERRI, GiovanniKNOBEL, MeyerYOSHIMURA, ElisabethCHAMMAS, Maria Cristina
Citation: LASERS IN SURGERY AND MEDICINE, v.44, n.4, p.357-357, 2012
Abstract: Background: Chronic autoimmune thyroiditis (CAT) frequently alters thyroid vascularization, likely as a result of the autoimmune process. Therefore, the objective of this study was to evaluate the effects of low-level laser therapy (LLLT) on the thyroid vascularization of patients with hypothyroidism induced by CAT using color Doppler ultrasound parameters. Study: A randomized clinical trial was conducted from 2006 to 2009 at the Hospital das Clínicas, University of Sao Paulo Medical School. Forty-three patients who underwent levothyroxine replacement for CAT-induced hypothyroidism were randomly assigned to receive either 10 sessions of LLLT (L group, n=23) or 10 sessions of a placebo treatment (P group, n=20). Color Doppler ultrasounds were performed before and 30 days after the end of the interventions. All of the patients in both groups continued taking their previous levothyroxine doses for the duration of the study. To verify the vascularization of the thyroid parenchyma, power Doppler was performed. The systolic peak velocity (SPV) and resistance index (RI) in the superior and inferior thyroid arteries were measured by pulsed Doppler. Results: All of the patients completed the study. The frequency of normal vascularization of the thyroid lobes observed in the post-intervention power Doppler examination was significantly higher in the L than in the P group (P=0.023). The pulsed Doppler examination revealed an increase in the SPV of the inferior thyroid arteries in the L group compared with the P group (P=0.016), whereas no significant difference in the SPV of the superior thyroid arteries was found between the groups. There was also no significant difference in the RI between the groups. Conclusion: These results suggest that LLLT can ameliorate thyroid parenchyma vascularization and increase the SPV of the inferior thyroid arteries of patients with hypothyroidism caused by CAT.
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Comunicações em Eventos - FM/MDR
Departamento de Radiologia - FM/MDR

Comunicações em Eventos - HC/ICHC
Instituto Central - HC/ICHC

Comunicações em Eventos - HC/InCor
Instituto do Coração - HC/InCor

Comunicações em Eventos - HC/InRad
Instituto de Radiologia - HC/InRad

Comunicações em Eventos - LIM/25
LIM/25 - Laboratório de Endocrinologia Celular e Molecular

Comunicações em Eventos - LIM/44
LIM/44 - Laboratório de Ressonância Magnética em Neurorradiologia

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