Influence of the Axcess Weight Loss on Control of Type II Diabetes After Gastric Bypass

Abstract

Introduction The gastric bypass has influence on the improvement of type II diabetes. The weight loss is related to amelioration of diabetes, but it is not clear the relationship between the amount of weight loss and diabetes control. Objective Analyze the influence of EWL on improving diabetes after one year of gastric bypass. Materials and methods 29 patients type II diabetes, 24 women and 5 men, meanage of 56.9 years, mean BMI: 48.2kg/m2, mean HbA1c: 8.1, underwent standard gastric bypass retrospectively analysed one year after operation with EWL>40 % (mean 57 %). Concerning diabetes control, the patients were divided into two groups: Group A, patients who achieve HbA1c <6.5 (n=21) and in group B those maintained HbA1c>6.5 (n=08). Results In all patients the decrease of mean A1c was significant (8.1 to 6.1, p<0.05). In both groups the decrease was also significant and similar (8 to 5.9 in group A, and 9.2 to 7.6 in group B). The %EWL in group A was 59 % and in group B 57 % (p>0.05) with no difference in the Mann Whitney test. Discussion With at least 40 % of EWL there was improvement on diabetes. In the patients who did not achieve the control target (A1c<6.5) the weight loss was similar that the patients who achieve it. Conclusion Weight loss after gastric bypass is an important factor for the improvement of type 2 diabetes. Despite of amelioration of diabetes in all patients studied, similar EWL in some patients did not result in control of the disease (A1c<6.5).