Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/2870
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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorSANTO, M. A.-
dc.contributor.authorRICCIOPPO, D.-
dc.contributor.authorPAJECKI, D.-
dc.contributor.authorKAWAMOTO, F.-
dc.contributor.authorMATSUDA, M.-
dc.contributor.authorCECCONELLO, I-
dc.date.accessioned2013-10-11T21:19:45Z-
dc.date.available2013-10-11T21:19:45Z-
dc.date.issued2012-
dc.identifier.citationOBESITY SURGERY, v.22, n.9, p.1408-1408, 2012-
dc.identifier.issn0960-8923-
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/2870-
dc.description.abstractIntroduction Currently obesity is an epidemic in Western society, with significant increase in prevalence. There are several comorbidities such as systemic hypertension, insulin resistance, dyslipidemia and NAFLD/NASH (Nonalcoholic Fatty Liver Diasease/Non alcoholic steatohepatitis). The liver biopsy is the gold standard for diagnosis of this condition. Due to several difficulties with this method, we compare some non-invasive markers for identification of severe/advanced fibrosis and cirrhosis. Materials & Methods We studied 638 patients undergoing bariatric surgery. Among them, 83 patients underwent liver biopsy. The laboratory data were obtained from medical records, and calculated the following markers: AAR, AP index, APRI, CDS and HALT-C. Using biopsies, performed in part of the serie (n=084), as a control group, statistical analysis was performed to identify the best method and cutoff values. Results The more accurate method was APRI, with a cutoff value of 0.6 (sensitivity and specificity, CI, PPV and NPV were calculated). In the group of patients who underwent biopsy, 5 had advanced fibrosis or cirrhosis (6.02 %) and 25 some degree of fibrosis (30.12 %). Discussion In the population studied, the percentages of fibrosis/cirrhosis, and some degree of NAFLD are compatible with literature data. The APRI index would be useful as a predictor in all cases of advanced fibrosis/cirrhosis in this serie. Conclusion Regarding the markers studied, the APRI was the best method to predict advanced liver disease. Thus, it can apparently be used as a screening method for performing liver biopsies.-
dc.language.isoeng-
dc.publisherSPRINGER-
dc.relation.ispartofObesity Surgery-
dc.rightsrestrictedAccess-
dc.titleEvaluation of Noninvasive Methods for Preoperative Diagnosis of Advanced Liver Fibrosis or Hepatic Cirrhosis in Morbid Obesity-
dc.typeconferenceObject-
dc.rights.holderCopyright SPRINGER-
dc.description.conferencedateSEP 11-15, 2012-
dc.description.conferencelocalNew Delhi, INDIA-
dc.description.conferencename17th World Congress of International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO)-
dc.subject.wosSurgery-
dc.type.categorymeeting abstract-
dc.type.versionpublishedVersion-
hcfmusp.description.beginpage1408-
hcfmusp.description.endpage1408-
hcfmusp.description.issue9-
hcfmusp.description.volume22-
hcfmusp.origemWOS-
hcfmusp.origem.idWOS:000308067800408-
hcfmusp.publisher.cityNEW YORK-
hcfmusp.publisher.countryUSA-
dc.description.indexMEDLINE-
Appears in Collections:

Comunicações em Eventos - FM/MGT
Departamento de Gastroenterologia - FM/MGT

Comunicações em Eventos - HC/ICHC
Instituto Central - HC/ICHC

Comunicações em Eventos - HC/InCor
Instituto do Coração - HC/InCor

Comunicações em Eventos - LIM/35
LIM/35 - Laboratório de Nutrição e Cirurgia Metabólica do Aparelho Digestivo


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