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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorSIQUEIRA, Jordana Herzog-
dc.contributor.authorMILL, Jose Geraldo-
dc.contributor.authorVELASQUEZ-MELENDEZ, Gustavo-
dc.contributor.authorMOREIRA, Alexandra Dias-
dc.contributor.authorBARRETO, Sandhi Maria-
dc.contributor.authorBENSENOR, Isabela Martins-
dc.contributor.authorMOLINA, Maria del Carmen Bisi-
dc.identifier.citationNUTRIENTS, v.10, n.8, article ID 981, 15p, 2018-
dc.description.abstractThe secular trend of hyperuricemia coincides with the substantial increase in the consumption of sugar-sweetened beverages. Our aim was to evaluate the association between the consumption of soft drinks, dietary fructose and unsweetened, non-processed fruit juices with hyperuricemia in a cross-sectional analysis of baseline data (2008-2010; n = 7173) of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). The explanatory variables were the consumption of soft drinks, fruit juice, and fructose using a validated semi-quantitative food frequency questionnaire. The outcomes were hyperuricemia and the uric acid concentration in serum. Regression models were tested, and a significance level of 5% was adopted. In men, the daily consumption of a portion of soft drink/day (250 mL) almost doubled the chance of hyperuricemia with a linear trend. In women, the consumption of 0.1 to <1.0 soft drink/day was associated with a higher chance of hyperuricemia, but there was no linear trend. High fructose consumption in men and moderate and high consumption in women were associated with hyperuricemia. All categories of soft drinks consumption were linearly associated with increased serum uric acid levels. Our findings suggest that the consumption of soft drinks and dietary fructose is positively associated with a higher chance of hyperuricemia and higher uric acid levels in Brazilian adults.-
dc.description.sponsorshipBrazilian Ministry of Health (Department of Science and Technology)-
dc.description.sponsorshipMinistry of Science, Technology and Innovation (FINEP, Financiadora de Estudos e Projetos) [01 06 0010.00, 01 06 0212.00, 01 06 0300.00, 01 06 0278.00, 01 06 0115.00, 01 06 0071.00]-
dc.description.sponsorshipCNPq (National Council for Scientific and Technological Development)-
dc.subjectsugar-sweetened soft drinks intake-
dc.subjectfruit and vegetable juices-
dc.subjecturic acid-
dc.subject.otherserum uric-acid-
dc.subject.othermetabolic syndrome-
dc.subject.otherbeverage consumption-
dc.titleSugar-Sweetened Soft Drinks and Fructose Consumption Are Associated with Hyperuricemia: Cross-Sectional Analysis from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)-
dc.rights.holderCopyright MDPI-
dc.subject.wosNutrition & Dietetics-
dc.type.categoryoriginal article-
dc.type.versionpublishedVersion-, Jordana Herzog:Univ Fed Espirito Santo, Ctr Ciencias Saude, BR-29042755 Vitoria, Brazil-, Jose Geraldo:Univ Fed Espirito Santo, Ctr Ciencias Saude, BR-29042755 Vitoria, Brazil-, Gustavo:Univ Fed Minas Gerais, Escola Enfermagem, BR-30130100 Belo Horizonte, MG, Brazil-, Alexandra Dias:Univ Fed Minas Gerais, Escola Enfermagem, BR-30130100 Belo Horizonte, MG, Brazil-, Sandhi Maria:Univ Fed Minas Gerais, Hosp Clin, BR-30130100 Belo Horizonte, MG, Brazil; Univ Fed Minas Gerais, Sch Med, BR-30130100 Belo Horizonte, MG, Brazil-, Maria del Carmen Bisi:Univ Fed Espirito Santo, Ctr Ciencias Saude, BR-29042755 Vitoria, Brazil-
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Artigos e Materiais de Revistas Científicas - FM/MCM
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Artigos e Materiais de Revistas Científicas - LIM/20
LIM/20 - Laboratório de Terapêutica Experimental

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