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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorSILVA-COSTA, Aline-
dc.contributor.authorGUIMARAES, Joanna-
dc.contributor.authorCHOR, Dora-
dc.contributor.authorFONSECA, Maria de Jesus Mendes da-
dc.contributor.authorBENSENOR, Isabela-
dc.contributor.authorSANTOS, Itamar-
dc.contributor.authorBARRETO, Sandhi-
dc.contributor.authorGRIEP, Rosane Harter-
dc.identifier.citationINTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH, v.91, n.5, p.591-600, 2018-
dc.description.abstractThe study of cardiovascular diseases (CVD) associated with night work is difficult due to the long period required for conditions to manifest and the healthy-worker effect. Analyzing asymptomatic pre-clinical changes in the atherosclerotic process is a way to assess the pathways between exposure to night work and CVD. To evaluate the associations between night work and subclinical atherosclerosis measured by carotid intima-media thickness (CIMT) using baseline data from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). We conducted cross-sectional analyses using baseline data (2008-2010) from 9785 civil servants, aged 35-74 years. The associations between time of exposure to night work and mean CIMT were examined using a structural equation model. The sample included 4259 men and 5526 women, mean age of 51.6 years. A total of 1778 (18.2%) individuals were exposed to night work (594 current and 1184 former night workers), and the mean years of night work exposed was 11.47 (SD = 9.45) years. On average, mean CIMT was 0.606 (SD = 0.130) mm. Among men, the increase in exposure to night work was significantly associated with an increase in BMI and CIMT. Among women, night work was not associated with increased CIMT. In relation to the indirect associations, results suggest a possible mediation by BMI, diabetes and hypertension on the association between the years of night work and mean CIMT only among men. Night work was associated with increased CIMT only among men. These findings add to the knowledge of the possible pathways that link night work and carotid atherosclerosis. Additionally, these results contribute to the recognition of work schedules as a public health problem that should be addressed by the medical community and policy makers.-
dc.description.sponsorshipBrazilian Ministry of Health (Science and Technology Department)-
dc.description.sponsorshipBrazilian Ministry of Science and Technology (Financiadora de Estudos e Projetos)-
dc.description.sponsorshipBrazilian Ministry of Science and Technology (CNPq National Research Council) [01 06 0010.00 RS, 0106 0212.00 BA, 01 06 0300.00 ES, 01 06 0278.00 MG, 01 06 0115.00 SP, 01 06 0071.00 RJ]-
dc.description.sponsorshipCNPq-Brasil [150551/2015-0]-
dc.relation.ispartofInternational Archives of Occupational and Environmental Health-
dc.subjectCarotid intima-media thickness-
dc.subjectWork schedule-
dc.subjectNight shift work-
dc.subject.otherintima-media thickness-
dc.subject.othercross-sectional analysis-
dc.subject.otherartery calcium score-
dc.subject.othershift work-
dc.titleTime of exposure to night work and carotid atherosclerosis: a structural equation modeling approach using baseline data from ELSA-Brasil-
dc.rights.holderCopyright SPRINGER-
dc.subject.wosPublic, Environmental & Occupational Health-
dc.type.categoryoriginal article-
dc.type.versionpublishedVersion-, Aline:Fed Univ Triangulo Mineiro UFTM, Dept Collect Hlth, Uberaba, MG, Brazil-, Joanna:Oswaldo Cruz Fdn FIOCRUZ, Sergio Arouca Natl Sch Publ Hlth, Rio De Janeiro, Brazil-, Dora:Oswaldo Cruz Fdn FIOCRUZ, Sergio Arouca Natl Sch Publ Hlth, Rio De Janeiro, Brazil-, Maria de Jesus Mendes da:Oswaldo Cruz Fdn FIOCRUZ, Sergio Arouca Natl Sch Publ Hlth, Rio De Janeiro, Brazil-, Sandhi:Fed Univ Minas Gerais UFMG, Dept Prevent & Social Med, Belo Horizonte, MG, Brazil-, Rosane Harter:Oswaldo Fdn FIOCRUZ, Lab Hlth & Environm Educ, Rio De Janeiro, Brazil-
hcfmusp.publisher.cityNEW YORK-
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Appears in Collections:

Artigos e Materiais de Revistas Científicas - FM/MCM
Departamento de Clínica Médica - FM/MCM

Artigos e Materiais de Revistas Científicas - LIM/20
LIM/20 - Laboratório de Terapêutica Experimental

Artigos e Materiais de Revistas Científicas - ODS/03
ODS/03 - Saúde e bem-estar

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