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Title: Health-related quality of life evaluation in patients with non-surgical benign tracheal stenosis
Authors: BIBAS, Benoit JacquesCARDOSO, Paulo Francisco GuerreiroSALATI, MicheleMINAMOTO, HelioTAMAGNO, Mauro Federico LuizTERRA, Ricardo MingariniPEGO-FERNANDES, Paulo Manuel
Citation: JOURNAL OF THORACIC DISEASE, v.10, n.8, p.4782-4788, 2018
Abstract: Background: The primary objective of the study was to evaluate the health-related quality of life (HRQL) of patients with benign post-intubation tracheal stenosis considered as unfit for surgical treatment. Secondary objectives were: (I) to determine if clinical variables (gender, age, total treatment time, and type of tracheal device) could influence HRQL and (II) to compare the results with a normal standardized population. Methods: Prospective study between August-2014 and December-2016 including patients with tracheal stenosis treated with silicone stents, T-Tubes or tracheostomy. Candidates to airway resection and reconstruction were excluded from the analysis. HRQL was assessed with the SF-36 Health Questionnaire. Backward stepwise regression model analyzed the influence of clinical variables on the SF-36 domains and component summaries. Norm-based results were compared with normative data. Alpha error was 5%. Results: Ninety-three patients (62M/31F; mean age 38 +/- 14 years) were included. Mean overall HRQL in all 8 SF-36 domains was poor. Lowest scores were in the role physical (mean 31.7 +/- 38), bodily pain (mean 39.2 +/- 35), and role emotional domain (mean 48.7 +/- 40). The physical component summary (PCS) was more affected than the mental (P<0.001). Norm-based results indicated that most domains and both physical and mental summaries were below the mean for the USA normative population. ]btal stenting time significantly influenced the physical (P=0.001) and mental component summaries (P=0.001). Conclusions: Quality of life of patients with benign tracheal stenosis is severely impaired, and norm-based results indicate that the HRQL is below normative data. Physical and mental discomfort seems to be attenuated by total treatment time.
Appears in Collections:Artigos e Materiais de Revistas Científicas - FM/MCP
Artigos e Materiais de Revistas Científicas - HC/ICESP
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - HC/InCor
Artigos e Materiais de Revistas Científicas - LIM/09
Artigos e Materiais de Revistas Científicas - LIM/61

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