Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorSANTO, Augusto Hasiak-
dc.contributor.authorPUECH-LEAO, Pedro-
dc.contributor.authorKRUTMAN, Mariana-
dc.identifier.citationBMC PUBLIC HEALTH, v.12, article ID 859, 18p, 2012-
dc.description.abstractBackground: Aortic aneurysm and dissection are important causes of death in older people. Ruptured aneurysms show catastrophic fatality rates reaching near 80%. Few population-based mortality studies have been published in the world and none in Brazil. The objective of the present study was to use multiple-cause-of-death methodology in the analysis of mortality trends related to aortic aneurysm and dissection in the state of Sao Paulo, between 1985 and 2009. Methods: We analyzed mortality data from the Sao Paulo State Data Analysis System, selecting all death certificates on which aortic aneurysm and dissection were listed as a cause-of-death. The variables sex, age, season of the year, and underlying, associated or total mentions of causes of death were studied using standardized mortality rates, proportions and historical trends. Statistical analyses were performed by chi-square goodness-of-fit and H Kruskal-Wallis tests, and variance analysis. The joinpoint regression model was used to evaluate changes in age-standardized rates trends. A p value less than 0.05 was regarded as significant. Results: Over a 25-year period, there were 42,615 deaths related to aortic aneurysm and dissection, of which 36,088 (84.7%) were identified as underlying cause and 6,527 (15.3%) as an associated cause-of-death. Dissection and ruptured aneurysms were considered as an underlying cause of death in 93% of the deaths. For the entire period, a significant increased trend of age-standardized death rates was observed in men and women, while certain non-significant decreases occurred from 1996/2004 until 2009. Abdominal aortic aneurysms and aortic dissections prevailed among men and aortic dissections and aortic aneurysms of unspecified site among women. In 1985 and 2009 death rates ratios of men to women were respectively 2.86 and 2.19, corresponding to a difference decrease between rates of 23.4%. For aortic dissection, ruptured and non-ruptured aneurysms, the overall mean ages at death were, respectively, 63.2, 68.4 and 71.6 years; while, as the underlying cause, the main associated causes of death were as follows: hemorrhages (in 43.8%/40.5%/13.9%); hypertensive diseases (in 49.2%/22.43%/24.5%) and atherosclerosis (in 14.8%/25.5%/15.3%); and, as associated causes, their principal overall underlying causes of death were diseases of the circulatory (55.7%), and respiratory (13.8%) systems and neoplasms (7.8%). A significant seasonal variation, with highest frequency in winter, occurred in deaths identified as underlying cause for aortic dissection, ruptured and non-ruptured aneurysms. Conclusions: This study introduces the methodology of multiple-causes-of-death to enhance epidemiologic knowledge of aortic aneurysm and dissection in Sao Paulo, Brazil. The results presented confer light to the importance of mortality statistics and the need for epidemiologic studies to understand unique trends in our own population.-
dc.relation.ispartofBMC Public Health-
dc.subjectAortic aneurysm and dissection-
dc.subjectHistorical trends-
dc.subject.otherunderlying cause-
dc.titleTrends in aortic aneurysm- and dissection-related mortality in the state of Sao Paulo, Brazil, 1985-2009: multiple-cause-of-death analysis-
dc.rights.holderCopyright BIOMED CENTRAL LTD-
dc.subject.wosPublic, Environmental & Occupational Health-
dc.type.categoryoriginal article-
dc.type.versionpublishedVersion-, Augusto Hasiak:Univ Sao Paulo, Fac Saude Publ, Dept Epidemiol, BR-01255 Sao Paulo, Brazil-
hcfmusp.relation.referenceAhmad OB, 2001, AGE STANDARDIZATION-
hcfmusp.relation.referenceAnjum A, 2012, BRIT J SURG, V99, P637, DOI 10.1002/bjs.8698-
hcfmusp.relation.referenceAnjum A, 2012, EUR J VASC ENDOVASC, V43, P161, DOI 10.1016/j.ejvs.2011.11.014-
hcfmusp.relation.referenceAyres M, 2007, BIOESTAT 5 0 STAT AP-
hcfmusp.relation.referenceBallaro A, 1998, EUR J VASC ENDOVASC, V15, P429, DOI 10.1016/S1078-5884(98)80205-0-
hcfmusp.relation.referenceBarros FS, 2005, J VASC BR, V4, P59-
hcfmusp.relation.referenceBest VA, 2003, BRIT J SURG, V90, P1510, DOI 10.1002/bjs.4342-
hcfmusp.relation.referenceBlanchard JF, 1999, EPIDEMIOL REV, V21, P207-
hcfmusp.relation.referenceBonamigo Telmo Pedro, 2003, Rev Hosp Clin Fac Med Sao Paulo, V58, P63-
hcfmusp.relation.referenceCASTLEDEN WM, 1985, BRIT J SURG, V72, P109, DOI 10.1002/bjs.1800720213-
hcfmusp.relation.referenceCenters for Disease Control and Prevention, AORT AN FACT SHEET-
hcfmusp.relation.referenceSharovsky Rodolfo, 2002, Arq Bras Cardiol, V78, P106-
hcfmusp.relation.referenceChoke E, 2012, CIRCULATION, V125, P1617, DOI 10.1161/CIRCULATIONAHA.111.077503-
hcfmusp.relation.referenceCoady Michael A., 1999, Cardiology Clinics, V17, P615, DOI 10.1016/S0733-8651(05)70105-3-
hcfmusp.relation.referenceFerreira SRG, 2009, REV SAUDE PUBL, V43, P98-
hcfmusp.relation.referenceFilipovic M, 2005, BRIT J SURG, V92, P968, DOI 10.1002/bjs.5118-
hcfmusp.relation.referenceFOWKES FGR, 1989, BRIT MED J, V298, P33-
hcfmusp.relation.referenceFranca E, 2008, INT J EPIDEMIOL, V37, P891, DOI 10.1093/ije/dyn121-
hcfmusp.relation.referenceGILLUM RF, 1995, J CLIN EPIDEMIOL, V48, P1289, DOI 10.1016/0895-4356(95)00045-3-
hcfmusp.relation.referenceGOLDACRE MJ, 1993, J EPIDEMIOL COMMUN H, V47, P491, DOI 10.1136/jech.47.6.491-
hcfmusp.relation.referenceGoodney PP, 2010, J VASC SURG, V51, P1340, DOI 10.1016/j.jvs.2010.01.054-
hcfmusp.relation.referenceGrootenboer N, 2010, BRIT J SURG, V97, P1169, DOI 10.1002/bjs.7134-
hcfmusp.relation.referenceHultgren R, 2007, EUR J VASC ENDOVASC, V33, P556, DOI 10.1016/j.ejvs.2006.11.030-
hcfmusp.relation.referenceIkeda MH, 2002, J VASC BR, V1, P89-
hcfmusp.relation.referenceISRAEL RA, 1986, AM J EPIDEMIOL, V124, P161-
hcfmusp.relation.referenceJohansson LA, 2002, J EPIDEMIOL COMMUN H, V56, P301, DOI 10.1136/jech.56.4.301-
hcfmusp.relation.referenceJoinpoint Regression Program, 2011, JOINP REGR PROGR VER-
hcfmusp.relation.referenceLake PB, 2001, AUST NZ J PUBL HEAL, V25, P31, DOI 10.1111/j.1467-842X.2001.tb00546.x-
hcfmusp.relation.referenceLILIENFELD DE, 1987, ARTERIOSCLEROSIS, V7, P637-
hcfmusp.relation.referenceManfredini R, 2004, J VASC SURG, V40, P382, DOI 10.1016/j.jvs.2004.04.019-
hcfmusp.relation.referenceMarjan U, 2012, J VASC SURG S, V55, p36S-
hcfmusp.relation.referenceMathers CD, 2005, B WORLD HEALTH ORGAN, V83, P171-
hcfmusp.relation.referenceMcGuiness H, 2006, AORTIC ANEURYSM DISS-
hcfmusp.relation.referenceMinisterio da Saude, 2007, RED INT INF SAUD IND-
hcfmusp.relation.referenceNational Center for Health Statistics, 1992, INSTR MAN 2C ICD 9 A-
hcfmusp.relation.referenceNational Center for Health Statistics, 2008, INSTR MAN 2C ICD 10-
hcfmusp.relation.referenceNational Center for Health Statistics, 2007, NCHS INSTR MAN 9-
hcfmusp.relation.referenceNational Center for Health Statistics National Vital Statistics System, 2007, DEATHS PERC TOT DEAT-
hcfmusp.relation.referenceNordon IM, 2011, NAT REV CARDIOL, V8, P92, DOI 10.1038/nrcardio.2010.180-
hcfmusp.relation.referenceNorman PE, 2011, J VASC SURG, V53, P274, DOI 10.1016/j.jvs.2010.08.087-
hcfmusp.relation.referencePanneton JM, 1995, ANN VASC SURG, V9, P535, DOI 10.1007/BF02018826-
hcfmusp.relation.referencePinheiro CE, 1998, REV SAUDE PUBL, V32, P72-
hcfmusp.relation.referencePuech-Leao Pedro, 2004, Sao Paulo Med J, V122, P158-
hcfmusp.relation.referenceRamanath VS, 2009, MAYO CLIN PROC, V84, P465, DOI 10.1016/S0025-6196(11)60566-1-
hcfmusp.relation.referenceRedelings MD, 2006, EPIDEMIOLOGY, V17, P100, DOI 10.1097/01.ede.0000187177.96138.c6-
hcfmusp.relation.referenceRedelings MD, 2007, AM J EPIDEMIOL, V166, P104, DOI 10.1093/aje/kwm037-
hcfmusp.relation.referenceRUSHTON L, 1994, OCCUP ENVIRON MED, V51, P722-
hcfmusp.relation.referenceRutherford RB, 1991, J VASC SURG, V13, P444-
hcfmusp.relation.referenceSakalihasan N, 2005, LANCET, V365, P1577, DOI 10.1016/S0140-6736(05)66459-8-
hcfmusp.relation.referenceSandiford P, 2011, BRIT J SURG, V98, P645, DOI 10.1002/bjs.7461-
hcfmusp.relation.referenceSanto AH, 2008, REV ASSOC MED BRAS, V54, P23-
hcfmusp.relation.referenceSanto AH, 1998, REV SAUDE PUBL, V32, P1-
hcfmusp.relation.referenceSanto Augusto Hasiak, 1995, Boletin de la Oficina Sanitaria Panamericana, V119, P319-
hcfmusp.relation.referenceSanto AH, 2000, REV SAUDE PUBL, V34, P21-
hcfmusp.relation.referenceSanto AH, 1999, REV BRAS EPIDEMIOL, V2, P90-
hcfmusp.relation.referenceSanto AH, 1988, THESIS U SAO PAULO S-
hcfmusp.relation.referenceSanto AH, 1994, THESIS U SAO PAULO S-
hcfmusp.relation.referenceSanto AH, 2000, INF EPIDEMIOL SUS, V9, P189-
hcfmusp.relation.referenceSanto AH, 2007, REV PANAM SALUD PUBL, V22, P178, DOI 10.1590/S1020-49892007000800004-
hcfmusp.relation.referenceSemmens JB, 2000, BRIT J SURG, V87, P191, DOI 10.1046/j.1365-2168.2000.01346.x-
hcfmusp.relation.referenceStallard E, 2002, N AM ACTUARIAL J, V<IT>6</IT>, P64-
hcfmusp.relation.referenceTALBOT S, 1972, POSTGRAD MED J, V48, P414-
hcfmusp.relation.referenceWanhainen A, 2008, BRIT J SURG, V95, P564, DOI 10.1002/bjs.6109-
hcfmusp.relation.referenceWilkins K., 1997, STAT CANADA HLTH REP, V<IT>9</IT>, P19-
hcfmusp.relation.referenceWorld Health Organization, 1992, INT CLASS DIS REL HL-
hcfmusp.relation.referenceWorld Health Organization, 1997, MAN INT STAT CLASS D-
hcfmusp.relation.referenceWorld Health Organization, 1993, INT CLASS DIS REL HL-
hcfmusp.relation.referenceWorld Health Organization, 1997, INT CLASS DIS TRANSL-
hcfmusp.relation.referenceYao-Hua H, 1993, TOHOKU J EXP MED, V171, P221-
Appears in Collections:

Artigos e Materiais de Revistas Científicas - FM/MCG
Departamento de Cirurgia - FM/MCG

Artigos e Materiais de Revistas Científicas - HC/ICHC
Instituto Central - HC/ICHC

Artigos e Materiais de Revistas Científicas - LIM/28
LIM/28 - Laboratório de Cirurgia Vascular e da Cabeça e Pescoço

Files in This Item:
File Description SizeFormat 
art_PUECH-LEAO_Trends_in_aortic_aneurysm_and_dissection_related_mortality_2012.PDFpublishedVersion (English)695.65 kBAdobe PDFThumbnail

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.