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Title: The human papillomavirus (HPV)-related cancer biology: An overview
Authors: ARALDI, Rodrigo PinheiroSANT'ANA, Thalita AraujoMODOLO, Diego GrandoMELO, Thatiana Correa deSPADACCI-MORENA, Diva DenelleSTOCCO, Rita de CassiaCERUTTI, Janete MariaSOUZA, Edislane Barreiros de
Citation: BIOMEDICINE & PHARMACOTHERAPY, v.106, p.1537-1556, 2018
Abstract: Despite the novel diagnostic methods and therapies implemented in oncology, the number of patients that succumb by the cancer remains high globally. Currently studies point out that 20-25% of all human malignancies are related to micro-organism infections. Among these cancer-related pathogens, the human papillomavirus (HPV) has a prominent position, since the virus is responsible for about 30% of all infectious agentrelated cancers. Thus, an amount of cancers could be avoided by means prophylactic and/or therapeutic measures. However, these measures required a holistic comprehension about HPV-related cancer biology. Based on this, this review aims to summarize the last evidences of HPV on cancer biology (from initiation to metastasis), focus on molecular and biochemical deregulations associated with viral infection, and discuss the viral etiology in different malignancies.
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Artigos e Materiais de Revistas Científicas - FM/Outros
Outros departamentos - FM/Outros

Artigos e Materiais de Revistas Científicas - LIM/31
LIM/31 - Laboratório de Genética e Hematologia Molecular

Artigos e Materiais de Revistas Científicas - ODS/03
ODS/03 - Saúde e bem-estar

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