Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/30010
Title: Oxytocin and Gynecomastia: Correlation or Causality?
Authors: AMORIM, LeticiaGOUVEIA, Flavia V.GERMANN, JurgenZAMBORI, DeboraMORAIS, RosaSATO, Flavia M.FONGARO, CamilaPORTOLESE, JoanaBRENTANI, HelenaMARTINEZ, Raquel
Citation: CUREUS, v.10, n.5, article ID UNSP e2661, 8p, 2018
Abstract: Oxytocin has been administered to patients with autism spectrum disorder (ASD) in order to improve social skills, communication, and manage repetitive behaviors in the context of research trials. The majority of the studies focus on acute administration; thus, the effectiveness and potential side effects of chronic administration remain unknown. The main goal of this case report is to highlight the importance of the safety parameters for the chronic use of intranasal oxytocin administration. In a single case conducted in our outpatient clinic, one adolescent (15 years old) received intranasal oxytocin (24 IU) twice per day, in accordance with the recommended doses for this age group that varies from 8 - 25 IU twice per day. After three weeks of treatment, the patient presented with gynecomastia. While it is not certain that the gynecomastia was oxytocin-induced, this case highlights the importance of developing optimal regimens for chronic oxytocin administration, with a particular focus on safety parameters.
Appears in Collections:Artigos e Materiais de Revistas Científicas - FM/MPS
Artigos e Materiais de Revistas Científicas - HC/IPq
Artigos e Materiais de Revistas Científicas - LIM/21

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