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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorSANTA-ROSA, F. A.
dc.contributor.authorSHIMOJO, G. L.
dc.contributor.authorSARTORI, M.
dc.contributor.authorROCHA, A. C.
dc.contributor.authorV, J. Francica
dc.contributor.authorPAIVA, J.
dc.contributor.authorIRIGOYEN, M. C.
dc.contributor.authorANGELIS, K. De
dc.identifier.citationBRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, v.51, n.12, article ID e7310, 5p, 2018
dc.description.abstractFamily history of hypertension is an important predictive factor for hypertension and is associated with hemodynamic and autonomic abnormalities. Previous studies reported that strength training might reduce arterial blood pressure (AP), as well as improve heart rate variability (HRV). However, the benefits of strength training in the offspring of hypertensive parents have not been fully evaluated. Here, we analyzed the impact of strength training on hemodynamics and autonomic parameters in offspring of hypertensive subjects. We performed a cross-sectional study with sedentary or physically active offspring of normotensives (S-ON and A-ON) or hypertensives (S-OH and A-OH). We recorded RR interval for analysis of HRV. AP was similar between groups. Sedentary offspring of hypertensives presented impairment of total variance of RR interval, as well as an increase in cardiac sympathovagal balance (S-OH: 4.2 +/- 0.7 vs S-ON: 2.8 +/- 0.4 and A-ON: 2.4 +/- 0.1). In contrast, the strength-trained group with a family history of hypertension did not show such dysfunctions. In conclusion, sedentary offspring of hypertensives, despite displaying no changes in AP, showed reduced HRV, reinforcing the hypothesis that autonomic dysfunctions have been associated with higher risk of hypertension onset. Our findings demonstrated that strength-trained offspring of hypertensives did not present impaired HRV, thus reinforcing the benefits of an active lifestyle in the prevention of early dysfunctions associated with the onset of hypertension in predisposed populations.eng
dc.description.sponsorshipCNPq [476373/2012-3, 457200/2014-6]
dc.description.sponsorshipCNPq-BPQ fellowships
dc.relation.ispartofBrazilian Journal of Medical and Biological Research
dc.subjectFamily historyeng
dc.subjectArterial blood pressureeng
dc.subjectCardiac autonomic modulationeng
dc.subjectSympathetic modulationeng
dc.subjectStrength trainingeng
dc.subject.othercardiac autonomic functioneng
dc.subject.othersympathetic activityeng
dc.titleFamilial history of hypertension-induced impairment on heart rate variability was not observed in strength-trained subjectseng
dc.rights.holderCopyright ASSOC BRAS DIVULG CIENTIFICAeng
dc.subject.wosMedicine, Research & Experimentaleng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng, F. A.:Univ Nove de Julho UNINOVE, Lab Fisiol Translac, Sao Paulo, SP, Brazil, G. L.:Univ Nove de Julho UNINOVE, Lab Fisiol Translac, Sao Paulo, SP, Brazil, A. C.:Univ Sao Judas Tadeu, Lab Movimento Humano, Sao Paulo, SP, Brazil, J. Francica:Univ Sao Judas Tadeu, Lab Movimento Humano, Sao Paulo, SP, Brazil, J.:Univ Nove de Julho UNINOVE, Lab Fisiol Translac, Sao Paulo, SP, Brazil, K. De:Univ Nove de Julho UNINOVE, Lab Fisiol Translac, Sao Paulo, SP, Brazil; Univ Fed Sao Paulo, Dept Fisiol, Sao Paulo, SP, Brazil
hcfmusp.publisher.citySAO PAULOeng
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Artigos e Materiais de Revistas Científicas - HC/InCor
Instituto do Coração - HC/InCor

Artigos e Materiais de Revistas Científicas - LIM/59
LIM/59 - Laboratório de Biologia Celular

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