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Title: Chronic liver failure treated by liver transplantation for patients with hepatitis C virus. An overview of the past 12 years
Citation: JOURNAL OF VIRAL HEPATITIS, v.19, suppl.3, Special Issue, p.30-30, 2012
Abstract: BACKGROUND: Hepatitis C virus (HCV) leads to chronic inflammation of the liverinabout 85% of infected individuals. Histologic features of chronic hepatitis develop in virtually all patients withchronic HCV infection,and cirrhosis develops in as many as 20% of patients within 10–20 years of HCV infection. Our aim is to analyzeboth patient andgraftsurvival rate over the past 12 years. MATERIAL AND METHODS: We have reviewed 35 articles published between 2000 and 2011. A total of 122,763 patients have undergone liver transplantation for HCV infection. The patient and graft survival rates in 1–3 years, 4–6 years and 7–10 years were analyzed. RESULTS: Overall patient survival rates were 1–3 years (76%), 4–6 years (20.44%), 7–10 years (19.3%). The graft survival rates were 1–3 years (48.76%), 4–6 years (17.95%), 7–10 years (22.24%). CONCLUSION: Virtually all patients become reinfected with HCV after transplantation, and histologic evidence of chronic hepatitis develops in about half of them within a few months. A recurrent liver failure appear to occur between 4 and 6 years with patient and graft survival rates of 20.44% and 17.95% respectively.
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Comunicações em Eventos - HC/ICHC
Instituto Central - HC/ICHC

Comunicações em Eventos - LIM/37
LIM/37 - Laboratório de Transplante e Cirurgia de Fígado

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