Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/31955
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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorMANUEL, Valdano
dc.contributor.authorMORAIS, Humberto
dc.contributor.authorTURQUETTO, Aida L. R.
dc.contributor.authorMIGUEL, Gade
dc.contributor.authorMIANA, Leonardo A.
dc.contributor.authorPEDRO, Albino
dc.contributor.authorNUNES, Maria A. S.
dc.contributor.authorLEON, Gilberto
dc.contributor.authorMAGALHAES, Manuel Pedro
dc.contributor.authorMARTINS, Telmo
dc.contributor.authorJUNIOR, Antonio P. F.
dc.date.accessioned2019-05-30T13:46:23Z
dc.date.available2019-05-30T13:46:23Z
dc.date.issued2019
dc.identifier.citationWORLD JOURNAL FOR PEDIATRIC AND CONGENITAL HEART SURGERY, v.10, n.2, p.164-170, 2019
dc.identifier.issn2150-1351
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/31955
dc.description.abstractIntroduction: Single ventricle physiology management is challenging, especially in low-income countries Objective: To report the palliation outcomes of single ventricle patients in a developing African country. Methods: We retrospectively studied 83 consecutive patients subjected to single ventricle palliation in a single center between March 2011 and December 2017. Preoperative data, surgical factors, postoperative results, and survival outcomes were analyzed. The patients were divided by palliation stage: I (pulmonary artery banding [PAB] or Blalock-Taussig shunt [BTS]), II (Glenn procedure), or III (Fontan procedure). Results: Of the 83 patients who underwent palliation (stages I-III), 38 deaths were observed (31 after stage I, six after stage II, and one after stage III) for an overall mortality of 45.7%. The main causes of operative mortality were multiple organ dysfunction due to sepsis, shunt occlusion, and cardiogenic shock. Twenty-eight survivors were lost to follow-up (22 after stage I, six after stage II). Thirteen stage II survivors are still waiting for stage III. The mean follow-up was 366 369 days. Five-year survival was 28.4 % for PAB and 30.1% for BTS, while that for stage II and III was 49.8% and 57.1%, respectively. Age (hazard ratio, 0.61; 95% confidence interval: 0.47-0.7; P = .000) and weight at surgery (hazard ratio, 0.45; 95% confidence interval: 0.31-0.64; P = .002) impacted survival. Conclusion: A high-mortality rate was observed in this initial experience, mainly in stage I patients. A large number of patients were lost to follow-up. A task force to improve outcomes is urgently required.eng
dc.language.isoeng
dc.publisherSAGE PUBLICATIONS INCeng
dc.relation.ispartofWorld Journal for Pediatric and Congenital Heart Surgery
dc.rightsrestrictedAccesseng
dc.subjectsingle ventricleeng
dc.subjectFontan procedureeng
dc.subjectGlenn procedureeng
dc.subjectBlalock-Taussig shunteng
dc.subjectpulmonary artery bandingeng
dc.subject.othercongenital heart-diseaseeng
dc.subject.otherblalock-taussig shunteng
dc.subject.otherbidirectional glenneng
dc.subject.otherfontan operationeng
dc.subject.othermortalityeng
dc.subject.otherchildreneng
dc.subject.otheroutcomeseng
dc.subject.otherinfantseng
dc.subject.otherriskeng
dc.subject.otherpredictorseng
dc.titleSingle Ventricle Palliation in a Developing Sub-Saharan African Country: What Should be Improved?eng
dc.typearticleeng
dc.rights.holderCopyright SAGE PUBLICATIONS INCeng
dc.identifier.doi10.1177/2150135118822671
dc.identifier.pmid30841832
dc.subject.wosCardiac & Cardiovascular Systemseng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng
hcfmusp.author.externalMORAIS, Humberto:Hosp Mil Principal, Inst Super, Cardiol Dept, Luanda, Angola
hcfmusp.author.externalMIGUEL, Gade:Clin Girassol, Cardiothorac Ctr, Luanda, Angola
hcfmusp.author.externalPEDRO, Albino:Clin Girassol, Cardiothorac Ctr, Luanda, Angola; Portuguese Red Cross Hosp, Pediat Cardiol Dept, Cardiac Surg Dept, Lisbon, Portugal
hcfmusp.author.externalNUNES, Maria A. S.:Clin Girassol, Cardiothorac Ctr, Luanda, Angola; Portuguese Red Cross Hosp, Pediat Cardiol Dept, Cardiac Surg Dept, Lisbon, Portugal
hcfmusp.author.externalLEON, Gilberto:Clin Girassol, Cardiothorac Ctr, Luanda, Angola
hcfmusp.author.externalMAGALHAES, Manuel Pedro:Clin Girassol, Cardiothorac Ctr, Luanda, Angola; Portuguese Red Cross Hosp, Pediat Cardiol Dept, Cardiac Surg Dept, Lisbon, Portugal
hcfmusp.author.externalMARTINS, Telmo:Clin Girassol, Cardiothorac Ctr, Luanda, Angola
hcfmusp.author.externalJUNIOR, Antonio P. F.:Clin Girassol, Cardiothorac Ctr, Luanda, Angola
hcfmusp.description.beginpage164
hcfmusp.description.endpage170
hcfmusp.description.issue2
hcfmusp.description.volume10
hcfmusp.origemWOS
hcfmusp.origem.idWOS:000461565700006
hcfmusp.origem.id2-s2.0-85062593295
hcfmusp.publisher.cityTHOUSAND OAKSeng
hcfmusp.publisher.countryUSAeng
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dc.description.indexMEDLINEeng
dc.identifier.eissn2150-136X
hcfmusp.citation.scopus4-
hcfmusp.scopus.lastupdate2022-06-10-
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