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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorEBRAHIMI, Ardalan
dc.contributor.authorGIL, Ziv
dc.contributor.authorAMIT, Moran
dc.contributor.authorYEN, Tzu-Chen
dc.contributor.authorLIAO, Chun-ta
dc.contributor.authorCHATURVEDI, Pankaj
dc.contributor.authorAGARWAL, Jai Prakash
dc.contributor.authorKOWALSKI, Luiz P.
dc.contributor.authorKOHLER, Hugo F.
dc.contributor.authorKREPPEL, Matthias
dc.contributor.authorCERNEA, Claudio R.
dc.contributor.authorBRANDAO, Jason
dc.contributor.authorBACHAR, Gideon
dc.contributor.authorVILLARET, Andrea Bolzoni
dc.contributor.authorFLISS, Dan M.
dc.contributor.authorFRIDMAN, Eran
dc.contributor.authorROBBINS, Kevin Thomas
dc.contributor.authorSHAH, Jatin P.
dc.contributor.authorPATEL, Snehal G.
dc.contributor.authorCLARK, Jonathan R.
dc.date.accessioned2019-06-26T17:26:27Z-
dc.date.available2019-06-26T17:26:27Z-
dc.date.issued2019
dc.identifier.citationHEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, v.41, n.6, p.1935-1942, 2019
dc.identifier.issn1043-3074
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/32394-
dc.description.abstractBackground We aimed to investigate whether depth of invasion (DOI) should be an independent indication for postoperative radiotherapy (PORT) in small oral squamous cell carcinomas (SCC). Methods Retrospective analysis of DOI (<5, 5 to <10, >= 10 mm) and disease-specific survival (DSS) in a multi-institutional international cohort of 1409 patients with oral SCC <= 4 cm in size treated between 1990-2011. Results In patients without other adverse factors (nodal metastases; close [<5 mm] or involved margins), there was no association between DOI and DSS, with an excellent prognosis irrespective of depth. In the absence of PORT, the 5-year disease-specific mortality was 10% with DOI >= 10 mm, 8% with DOI 5-10 mm, and 6% with DOI <5 mm (P = .169), yielding an absolute risk difference of only 4%. Conclusion The deterioration in prognosis with increasing DOI largely reflects an association with other adverse features. In the absence of these, depth alone should not be an indication for PORT outside a clinical trial.eng
dc.description.sponsorshipNCI NIH HHS [P30 CA008748]
dc.language.isoeng
dc.publisherWILEYeng
dc.relation.ispartofHead and Neck-Journal for the Sciences and Specialties of the Head and Neck
dc.rightsrestrictedAccesseng
dc.subjectdepth of invasioneng
dc.subjecthead and neck cancereng
dc.subjectlocoregional controleng
dc.subjectoral squamous cell carcinomaeng
dc.subjectradiotherapyeng
dc.subjectsurvivaleng
dc.subjecttumor thicknesseng
dc.subject.othertumor thicknesseng
dc.subject.otherprognostic-significanceeng
dc.subject.otherneck dissectioneng
dc.subject.othertongueeng
dc.subject.othercancereng
dc.subject.othersurvivaleng
dc.subject.othercavityeng
dc.subject.otherstageeng
dc.subject.otherriskeng
dc.subject.otherpatterneng
dc.titleDepth of invasion alone as an indication for postoperative radiotherapy in small oral squamous cell carcinomas: An International Collaborative Studyeng
dc.typearticleeng
dc.rights.holderCopyright WILEYeng
dc.contributor.groupauthorIntl Consortium Outcome Res ICOR
dc.description.conferencedate2014
dc.description.conferencelocalDarwin, AUSTRALIA
dc.description.conferencenameAnnual Meeting of the Australian-and-New-Zealand-Head-and-Neck-Cancer-Society
dc.identifier.doi10.1002/hed.25633
dc.identifier.pmid30801885
dc.subject.wosOtorhinolaryngologyeng
dc.subject.wosSurgeryeng
dc.type.categoryarticle; proceedings papereng
dc.type.versionpublishedVersioneng
hcfmusp.author.externalEBRAHIMI, Ardalan:Royal Prince Alfred Hosp, Sydney Head & Neck Canc Inst, Sydney, NSW, Australia; Canberra Hosp, Dept Head & Neck Surg, Canberra, ACT, Australia; Macquarie Univ, Australian Sch Adv Med, Sydney, NSW, Australia; Australian Natl Univ, Sch Med, Coll Hlth & Med, Canberra, ACT, Australia
hcfmusp.author.externalGIL, Ziv:Technion Israel Inst Technol, Lab Appl Canc Res, Haifa, Israel; Technion Israel Inst Technol, Rappaport Sch Med, Rambam Med Ctr, Dept Otolaryngol, Haifa, Israel
hcfmusp.author.externalAMIT, Moran:Technion Israel Inst Technol, Lab Appl Canc Res, Haifa, Israel; Technion Israel Inst Technol, Rappaport Sch Med, Rambam Med Ctr, Dept Otolaryngol, Haifa, Israel
hcfmusp.author.externalYEN, Tzu-Chen:Chang Gung Mem Hosp, Dept Nucl Med, Taoyuan, Taiwan; Chang Gung Mem Hosp, Mol Imaging Ctr, Taoyuan, Taiwan
hcfmusp.author.externalLIAO, Chun-ta:Chang Gung Mem Hosp, Dept Otorhinolaryngol Head & Neck Surg, Taoyuan, Taiwan
hcfmusp.author.externalCHATURVEDI, Pankaj:Tata Mem Hosp, Dept Head & Neck Surg, Mumbai, Maharashtra, India
hcfmusp.author.externalAGARWAL, Jai Prakash:Tata Mem Hosp, Dept Radiat Oncol, Mumbai, Maharashtra, India
hcfmusp.author.externalKOWALSKI, Luiz P.:Hosp AC Camargo Fund Antonio Prudente, Dept Head & Neck Surg, Sao Paulo, Brazil
hcfmusp.author.externalKOHLER, Hugo F.:Hosp AC Camargo Fund Antonio Prudente, Dept Head & Neck Surg, Sao Paulo, Brazil
hcfmusp.author.externalKREPPEL, Matthias:Univ Cologne, Dept Oral & Craniomaxillo & Facial Plast Surg, Cologne, Germany
hcfmusp.author.externalBRANDAO, Jason:Univ Sao Paulo, Sch Med, Dept Head & Neck Surg, Sao Paulo, Brazil
hcfmusp.author.externalBACHAR, Gideon:Rabin Med Ctr, Dept Otolaryngol Head & Neck Surg, Petah Tiqwa, Israel
hcfmusp.author.externalVILLARET, Andrea Bolzoni:Univ Brescia, Dept ENT, Brescia, Italy
hcfmusp.author.externalFLISS, Dan M.:Tel Aviv Med Ctr & Sch Med, Dept Otolaryngol Head & Neck Surg, Tel Aviv, Israel
hcfmusp.author.externalFRIDMAN, Eran:Tel Aviv Med Ctr & Sch Med, Dept Otolaryngol Head & Neck Surg, Tel Aviv, Israel
hcfmusp.author.externalROBBINS, Kevin Thomas:Southern Illinois Univ, Sch Med, Div Otolaryngol Head & Neck Surg, Springfield, IL USA
hcfmusp.author.externalSHAH, Jatin P.:Mem Sloan Kettering Canc Ctr, Head & Neck Surg Serv, 1275 York Ave, New York, NY 10021 USA
hcfmusp.author.externalPATEL, Snehal G.:Mem Sloan Kettering Canc Ctr, Head & Neck Surg Serv, 1275 York Ave, New York, NY 10021 USA
hcfmusp.author.externalCLARK, Jonathan R.:Royal Prince Alfred Hosp, Sydney Head & Neck Canc Inst, Sydney, NSW, Australia; Univ New South Wales, Sch Med, Sydney, NSW, Australia; Univ Sydney, Sch Med, Sydney, NSW, Australia
hcfmusp.description.beginpage1935
hcfmusp.description.endpage1942
hcfmusp.description.issue6
hcfmusp.description.volume41
hcfmusp.origemWOS
hcfmusp.origem.idWOS:000468629500049
hcfmusp.origem.id2-s2.0-85062373816
hcfmusp.publisher.cityHOBOKENeng
hcfmusp.publisher.countryUSAeng
hcfmusp.relation.referenceAl-Rajhi N, 2000, ORAL ONCOL, V36, P508, DOI 10.1016/S1368-8375(00)00042-7eng
hcfmusp.relation.referenceAmin MB, 2017, AJCC CANC STAGING MAeng
hcfmusp.relation.referenceBrandwein-Gensler A, 2005, AM J SURG PATHOL, V29, P167eng
hcfmusp.relation.referenceBrennan S, 2010, HEAD NECK-J SCI SPEC, V32, P191, DOI 10.1002/hed.21167eng
hcfmusp.relation.referenceChang YC, 2010, HISTOPATHOLOGY, V57, P295, DOI 10.1111/j.1365-2559.2010.03616.xeng
hcfmusp.relation.referenceClark JR, 2006, OTOLARYNG HEAD NECK, V135, P748, DOI 10.1016/j.otohns.2006.05.751eng
hcfmusp.relation.referenceDissanayaka WL, 2012, OR SURG OR MED OR PA, V113, P518, DOI 10.1016/j.oooo.2011.11.001eng
hcfmusp.relation.referenceEbrahimi A, 2014, JAMA OTOLARYNGOL, V140, P1138, DOI 10.1001/jamaoto.2014.1548eng
hcfmusp.relation.referenceFan KH, 2010, INT J RADIAT ONCOL, V77, P1024, DOI 10.1016/j.ijrobp.2009.06.064eng
hcfmusp.relation.referenceGanly I, 2013, CANCER-AM CANCER SOC, V119, P1168, DOI 10.1002/cncr.27872eng
hcfmusp.relation.referenceGonzalez-Moles MA, 2002, ORAL ONCOL, V38, P394, DOI 10.1016/S1368-8375(01)00081-1eng
hcfmusp.relation.referenceHowaldt HP, 1999, J CRANIO MAXILL SURG, V27, P275, DOI 10.1054/jcms.1999.0070eng
hcfmusp.relation.referenceHuang SH, 2013, MED ORAL PATOL ORAL, V18, pE233, DOI 10.4317/medoral.18772eng
hcfmusp.relation.referenceKang CJ, 2011, INT J RADIAT ONCOL, V81, pE223, DOI 10.1016/j.ijrobp.2011.03.060eng
hcfmusp.relation.referenceKerawala C, 2016, J LARYNGOL OTOL, V130, pS83, DOI 10.1017/S0022215116000499eng
hcfmusp.relation.referenceLiao CT, 2012, INT J RADIAT ONCOL, V82, P284, DOI 10.1016/j.ijrobp.2010.09.036eng
hcfmusp.relation.referenceLing W, 2013, J ORAL MAXIL SURG, V71, P775, DOI 10.1016/j.joms.2012.09.026eng
hcfmusp.relation.referenceMishra RC, 1999, EUR J SURG ONCOL, V25, P186, DOI 10.1053/ejso.1998.0624eng
hcfmusp.relation.referenceMOORE C, 1986, ARCH SURG-CHICAGO, V121, P1410eng
hcfmusp.relation.referenceNational Comprehensive Cancer Network, HEAD NECK CANC VERSeng
hcfmusp.relation.referenceO'Brien CJ, 2003, HEAD NECK-J SCI SPEC, V25, P937, DOI 10.1002/hed.10324eng
hcfmusp.relation.referencePentenero M, 2005, HEAD NECK-J SCI SPEC, V27, P1080, DOI 10.1002/hed.20275eng
hcfmusp.relation.referenceRahima B, 2004, ORAL SURG ORAL MED O, V97, P423, DOI 10.1016/j.tripleo.2003.10.014eng
hcfmusp.relation.referenceSciubba JJ, 2006, LANCET ONCOL, V7, P175, DOI 10.1016/S1470-2045(06)70580-0eng
hcfmusp.relation.referenceShim SJ, 2010, RADIAT ONCOL, V5, DOI 10.1186/1748-717X-5-43eng
hcfmusp.relation.referenceTai SK, 2012, HEAD NECK-J SCI SPEC, V34, P994, DOI 10.1002/hed.21846eng
hcfmusp.relation.referenceTan WJ, 2012, ORL J OTO-RHINO-LARY, V74, P264, DOI 10.1159/000343796eng
hcfmusp.relation.referenceURIST MM, 1987, AM J SURG, V154, P411, DOI 10.1016/0002-9610(89)90014-7eng
hcfmusp.relation.referenceYuen APW, 2000, AM J SURG, V180, P139, DOI 10.1016/S0002-9610(00)00433-5eng
hcfmusp.relation.referenceYuen APW, 2002, HEAD NECK-J SCI SPEC, V24, P513, DOI 10.1002/hed.10094eng
dc.description.indexMEDLINEeng
dc.identifier.eissn1097-0347
hcfmusp.citation.scopus18-
hcfmusp.scopus.lastupdate2022-05-06-
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Artigos e Materiais de Revistas Científicas - FM/MCG
Departamento de Cirurgia - FM/MCG

Artigos e Materiais de Revistas Científicas - HC/ICHC
Instituto Central - HC/ICHC

Artigos e Materiais de Revistas Científicas - LIM/28
LIM/28 - Laboratório de Cirurgia Vascular e da Cabeça e Pescoço

Artigos e Materiais de Revistas Científicas - ODS/03
ODS/03 - Saúde e bem-estar


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