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Title: Health effects of dietary risks in 195 countries, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017
Authors: AFSHIN, AshkanSUR, Patrick JohnFAY, Kairsten A.CORNABY, LeslieFERRARA, GianninaSALAMA, Joseph S.MULLANY, Erin C.ABATE, Kalkidan HassenABBAFATI, CristianaABEBE, ZegeyeAFARIDEH, MohsenAGGARWAL, AnjuAGRAWAL, SutapaAKINYEMIJU, TomiALAHDAB, FaresBACHA, UmarBACHMAN, Victoria F.BADALI, HamidBADAWI, AlaaBENSENOR, Isabela M.BERNABE, EduardoBIRYUKOV, Stan H.BIADGILIGN, Sibhatu Kassa K.CAHILL, Leah E.CARRERO, Juan J.CERCY, Kelly M.DANDONA, LalitDANDONA, RakhiAnh Kim DangDEGEFA, Meaza GirmaZAKI, Maysaa El SayedESTEGHAMATI, AlirezaESTEGHAMATI, SadafFANZO, JessicaFARINHA, Carla Sofia E. SaFARVID, Maryam S.FARZADFAR, FarshadFEIGIN, Valery L.FERNANDES, Joao C.FLOR, Luisa SorioFOIGT, Nataliya A.FOROUZANFAR, Mohammad H.GANJI, MorsalehGELEIJNSE, Johanna M.GILLUM, Richard F.GOULART, Alessandra C.GROSSO, GiuseppeGUESSOUS, IdrisHAMIDI, SamerHANKEY, Graeme J.HARIKRISHNAN, SivadasanpillaiHASSEN, Hamid YimamHAY, Simon I.Chi Linh HoangHORINO, MasakoISLAMI, FarhadJACKSON, Maria D.JAMES, Spencer L.JOHANSSON, LarsJONAS, Jost B.KASAEIAN, AmirKHADER, Yousef SalehKHALIL, Ibrahim A.KHANG, Young-HoKIMOKOTI, Ruth W.KOKUBO, YoshihiroKUMAR, G. AnilLALLUKKA, TeaLOPEZ, Alan D.LORKOWSKI, StefanLOTUFO, Paulo A.LOZANO, RafaelMALEKZADEH, RezaMARZ, WinfriedMEIER, ToniMELAKU, Yohannes A.MENDOZA, WalterMENSINK, Gert B. M.MICHA, RenataMILLER, Ted R.MIRAREFIN, MojdeMOHAN, ViswanathanMOKDAD, Ali H.MOZAFFARIAN, DariushNAGEL, GabrieleNAGHAVI, MohsenCuong Tat NguyenNIXON, Molly R.ONG, Kanyin L.PEREIRA, David M.POUSTCHI, HosseinQORBANI, MostafaRAI, Rajesh KumarRAZO-GARCIA, ChristianREHM, Colin D.RIVERA, Juan A.RODRIGUEZ-RAMIREZ, SoniaROSHANDEL, GholamrezaROTH, Gregory A.SANABRIA, JuanSANCHEZ-PIMIENTA, Tania G.SARTORIUS, BennSCHMIDHUBER, JosefSCHUTTE, Aletta ElisabethSEPANLOU, Sadaf G.SHIN, Min-JeongSORENSEN, Reed J. D.SPRINGMANN, MarcoSZPONAR, LucjanTHORNE-LYMAN, Andrew L.THRIFT, Amanda G.TOUVIER, MathildeBach Xuan TranTYROVOLAS, StefanosUKWAJA, Kingsley NnannaULLAH, IrfanUTHMAN, Olalekan A.VAEZGHASEMI, MasoudVASANKARI, Tommi JuhaniVOLLSET, Stein EmilTheo VosGiang Thu VuLinh Gia VuWEIDERPASS, ElisabeteWERDECKER, AndreaWIJERATNE, TissaWILLETT, Walter C.WU, Jason H.XU, GelinYONEMOTO, NaohiroYU, ChuanhuaMURRAY, Christopher J. L.
Citation: LANCET, v.393, n.10184, p.1958-1972, 2019
Abstract: Background Suboptimal diet is an important preventable risk factor for non-communicable diseases (NCDs); however, its impact on the burden of NCDs has not been systematically evaluated. This study aimed to evaluate the consumption of major foods and nutrients across 195 countries and to quantify the impact of their suboptimal intake on NCD mortality and morbidity. Methods By use of a comparative risk assessment approach, we estimated the proportion of disease-specific burden attributable to each dietary risk factor (also referred to as population attributable fraction) among adults aged 25 years or older. The main inputs to this analysis included the intake of each dietary factor, the effect size of the dietary factor on disease endpoint, and the level of intake associated with the lowest risk of mortality. Then, by use of diseasespecific population attributable fractions, mortality, and disability-adjusted life-years (DALYs), we calculated the number of deaths and DALYs attributable to diet for each disease outcome. Findings In 2017, 11 million (95% uncertainty interval [UI] 10-12) deaths and 255 million (234-274) DALYs were attributable to dietary risk factors. High intake of sodium (3 million [1-5] deaths and 70 million [34-118] DALYs), low intake of whole grains (3 million [2-4] deaths and 82 million [59-109] DALYs), and low intake of fruits (2 million [1-4] deaths and 65 million [41-92] DALYs) were the leading dietary risk factors for deaths and DALYs globally and in many countries. Dietary data were from mixed sources and were not available for all countries, increasing the statistical uncertainty of our estimates. Interpretation This study provides a comprehensive picture of the potential impact of suboptimal diet on NCD mortality and morbidity, highlighting the need for improving diet across nations. Our findings will inform implementation of evidence-based dietary interventions and provide a platform for evaluation of their impact on human health annually.
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Artigos e Materiais de Revistas Científicas - FM/MCM
Departamento de Clínica Médica - FM/MCM

Artigos e Materiais de Revistas Científicas - HU
Hospital Universitário - HU

Artigos e Materiais de Revistas Científicas - LIM/20
LIM/20 - Laboratório de Terapêutica Experimental

Artigos e Materiais de Revistas Científicas - LIM/51
LIM/51 - Laboratório de Emergências Clínicas

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