Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/33487
Title: Microbiota and nonalcoholic fatty liver disease/nonalcoholic steatohepatitis (NAFLD/NASH)
Authors: DUARTE, Sebastiao M. B.STEFANO, Jose TadeuOLIVEIRA, Claudia P.
Citation: ANNALS OF HEPATOLOGY, v.18, n.3, p.416-421, 2019
Abstract: Genetic predisposition, the intestinal microbiota (IM) and environmental factors, such as sedentary lifestyle and inadequate diet, should be considered as critical factors for the development of nonalcoholic fatty liver disease (NAFLD). Recently, some studies have demonstrated an association between dysbiosis and NAFLD; however, the exact mechanisms that lead to intestinal membrane damage, bacterial translocation and inflammation are not well elucidated. Due to the relevance of this theme, the IM and its metabolites have received special attention in recent years in an attempt to better understand the mechanisms related to the prevention, physiopathology, and treatment of NAFLD. In this paper, we provide a review of the human IM and its role in diet, obesity, and the development/progression of NAFLD/NASH, as well as the use of prebiotics and probiotics in the modulation of IM. (C) 2019 Fundacion Clinica Medica Sur, A.C.
Appears in Collections:

Artigos e Materiais de Revistas Científicas - FM/MGT
Departamento de Gastroenterologia - FM/MGT

Artigos e Materiais de Revistas Científicas - LIM/07
LIM/07 - Laboratório de Gastroenterologia Clínica e Experimental


Files in This Item:
File Description SizeFormat 
art_DUARTE_Microbiota_and_nonalcoholic_fatty_liver_diseasenonalcoholic_steatohepatitis_NAFLDNASH_2019.PDF
  Restricted Access
publishedVersion (English)1.64 MBAdobe PDFView/Open Request a copy

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.